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Proteomic signatures enhance risk prediction for both common and rare diseases

Researchers have developed sparse prediction models combining plasma proteins and clinical data to predict the 10-year risk of 218 diseases. The study, involving over 41,000 participants, highlights the enhanced predictive power of proteomic signatures.

24 Jul 2024

Associations between gut microbes and Alzheimer’s disease

Researchers reviewed existing data on the role of the gut microbiome in Alzheimer’s disease (AD) pathogenesis.

24 Jul 2024

Porcine study reveals meurotoxic and pro-inflammatory effects of microplastics on enteric nervous system

Researchers investigates the effects of polyethylene terephthalate microplastics on the neuronal population in the porcine jejunum.

18 Jul 2024

Distinct signaling pathway drives the transformation of epithelial cells into aggressive tumors

A distinct signaling pathway called TNF-α drives the transformation of epithelial cells into aggressive tumor cells.

18 Jul 2024

Frequent infections and pathobionts boost children's nasal immunity, study reveals

Dynamic interactions with viruses and bacterial pathobionts significantly enhance nasal innate immunity in children, revealing distinct immunophenotypes driven by microbial load and type.

2 Jul 2024

Study reveals refined carbs heighten inflammation and cardiovascular risk

A study in Nutrients journal finds that both the quantity and quality of carbohydrates impact inflammation and cardiovascular disease (CVD) risk. Higher refined carbohydrate intake is linked to greater inflammation and CVD, emphasizing the need for personalized dietary recommendations.

2 Jul 2024

Targeting the gut microbiome: A new approach to treating diabetes

Researchers review the role of gut microbiota in the pathogenesis and management of diabetes mellitus.

24 Jun 2024

Can nuts boost weight loss and blood sugar control on a calorie-restricted diet?

Researchers compared the effects of energy-restricted (ER) dietary patterns with nuts or without on body composition, weight, and glycemic management.

21 Jun 2024

Genetic discovery reveals key to inflammatory diseases

Researchers discovered that a specific haplotype on chromosome 21 is linked to five inflammatory diseases, offering insights into potential new treatments.

7 Jun 2024

Cervix organ chips pave the way for next-generation studies on host-microbiome interactions

A group of researchers developed human Cervical Organ Chips to model the cervical interface.

4 Jun 2024

Young bone marrow transplants show promise in reversing Alzheimer's symptoms in mice

Researchers found that young bone marrow transplants rejuvenate aging immune cells, reducing Alzheimer's symptoms in mice models, suggesting a potential therapeutic approach for the disease.

4 Jun 2024

Statins found to prevent chronic inflammation-related cancers by inhibiting interleukin-33

The effects of statins via inhibition of interleukin 33 (IL-33).

3 Jun 2024

Omega-3 supplements show promise in battling osteoarthritis

A recent study in Nutrients reviewed the efficacy of omega-3 polyunsaturated fatty acids (PUFAs) in slowing the progression of osteoarthritis (OA) by reducing inflammation and supporting joint health.

2 Jun 2024

Running therapy matches antidepressants for mental health, surpasses for physical benefits

Researchers found that while both antidepressants and group running therapy effectively improved mental health in patients with anxiety and depression, running therapy had significantly better outcomes for physical health indicators.

26 May 2024

New study identifies key protein biomarkers for early detection of pancreatic cancer

Study used a Mendelian randomization approach to identify REG1A and REG1B as potential biomarkers for early detection of pancreatic cancer, showing their causal effects and significance in cancer screening.

19 May 2024

Mechanistic insights into the role of huc-mscs in treating acute liver failure

Acute liver failure (ALF) is a life-threatening clinical problem with limited treatment options. Administration of human umbilical cord mesenchymal stem cells (hUC-MSCs) may be a promising approach for ALF.

16 May 2024

Menthol-derived molecules: promising candidates for anti-inflammatory and anti-obesity therapy

Modified derivatives of natural products have led to significant therapeutic advances and commercial success in recent times.

15 May 2024

Curcuminoid compounds show promise against COVID-19 in neuronal cells

The effects of curcumin and curcuminoids on a human neuroblastoma cell line (SH-SY5Y) infected with SARS-CoV-2.

14 May 2024

Study shows that high Mediterranean dietary adherence lowers systemic inflammation in elders

The relationship between high Mediterranean dietary pattern (MDP) adherence and decreased low-grade systemic inflammation.

7 May 2024

Neural circuits revealed as key regulators in body's immune response, study finds

A recent study in Nature reveals how specific neural circuits within the body-brain axis regulate immune responses, highlighting potential new therapeutic approaches for immune disorders.

6 May 2024