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Urban Britain is a recipe for heart disease

Researchers at The University of Manchester’s Medical School, working with teams in India and Birmingham, have found that people moving from South Asia to the UK significantly increase their risk of contracting cardiovascular disease (CVD).

From The University of Manchester 9 Nov 2005

Chlamydia pneumoniae may cause vision problems

Researchers at the Massachusetts Eye and Ear Infirmary (MEEI) have found that Chlamydia pneumoniae, a bacterium linked to heart disease and capable of causing chronic inflammation, was present in the diseased eye tissue of five out of nine people with neovascular, or "wet," age-related macular degeneration (AMD).

7 Nov 2005

Ultrasound to view heart's interior in three dimensions

Duke University engineers are developing technology that may enable physicians to someday use high frequency ultrasound waves both to visualize the heart's interior in three dimensions and then selectively destroy heart tissue with heat to correct arrhythmias.

7 Nov 2005

Important breakthrough in developing the drugs of the future

Their work on targeting individual genes for more effective and cheaper drug testing opens the way to treatments for a huge range of diseases including diabetes and atherosclerosis, which leads to strokes and heart attacks.

3 Nov 2005

Paclitaxel may help treat scleroderma

Using a novel model for scleroderma, researchers from Duke University Medical Center have discovered two important insights into this devastating disorder - the anti-cancer drug paclitaxel (Taxol) may prevent the skin thickening and small blood vessel destruction that characterizes the disease.

1 Nov 2005

Discovery of signaling mechanism may help prevent metastatic melanoma

Researchers at Northwestern University have discovered a key signaling mechanism that may promote the ability of highly aggressive malignant melanoma cells to metastasize, or spread from a primary tumor to distant sites within the body.

1 Nov 2005

First study to confirm the benefit of anti-angiogenic therapy in patients with breast cancer

Results from the first and only interim analysis of an important trial assessing the potential of Herceptin (trastuzumab) to improve disease-free survival (DFS) in HER-2 positive breast cancer patients after adjuvant chemotherapy, have shown that Herceptin affords a significant survival advantage.

1 Nov 2005

Two competing drug-eluting stents work equally well

After completing the most comprehensive U.S.-based study of its kind, Dr. Charles Simonton reported that the performance of two competing coronary stents was "virtually identical" in head-to-head comparisons.

25 Oct 2005

How cells use very slow biological flows to signal and organize

An EPFL (Ecole Polytechnique Federale de Lausanne) team led by professor Melody Swartz has demonstrated for the first time that the presence of very slow biological flows affects the extracellular environment in ways that are critical for tissue formation and cell migration.

25 Oct 2005

Scientists gain better understanding of how repetitive stretching of endothelial cells that line arteries can make them healthy and resistant to vascular diseases

UCSD researchers stretched cells in a workout chamber the size of a credit card to gain a better understanding of how repetitive stretching of endothelial cells that line arteries can make them healthy and resistant to vascular diseases.

24 Oct 2005

Nitric oxide may help sickle cell patients

Inhaling a small dose of nitric oxide gas may one day help sickle cell patients avoid pain crises and live healthier lives, researchers say.

23 Oct 2005

Mixed carbon nanotubes and standard urban particulates suggests a risk of thrombosis from airborne pollution

Carbon nanoparticles - both those unleashed in the air by engine exhaust and the engineered structures thought to have great potential in medical applications - promote blood-clotting, scientists report in an upcoming edition of the British Journal of Pharmacology.

23 Oct 2005

Yeast cells help show how GSAO (glutathionarsenoxide) angiogenesis inhibitor drug works

The humble yeast has revealed the molecular workings of an anti-cancer drug that stops the growth and spread of tumours in humans by starving their blood supply.

18 Oct 2005

Treating four or more brain tumors in a single radiosurgery session resulted in improved survival

...compared to whole brain radiation therapy alone, according to a study the University of Pittsburgh School of Medicine presented today at the 47th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) in Denver.

18 Oct 2005

Moderate drinking has effects on blood coagulation, primarily as a "blood thinner"

Population studies have shown that moderate drinkers tend to have lower rates of heart disease but higher rates of bleeding-type strokes than abstainers. A potential mediator of these two contrasting effects of alcohol may be platelet function.

13 Oct 2005

Erectile dysfunction may be a sign that coronary artery disease is developing

"We think that erectile dysfunction represents the 'tip of the iceberg' of a systemic vascular disorder; thus potentially preceding severe cardiovascular events. Erectile dysfunction should be part of a cardiovascular risk assessment.

11 Oct 2005

Obesity linked to dementia and Alzheimer's disease

Individuals who were obese at midlife had an increased risk for dementia later in life compared to individuals of normal weight, according to an article in the October issue of Archives of Neurology.

10 Oct 2005

Electron-beam computed tomography - a more accurate replacement for coronary catheterizations

Electron-beam computed tomography (EBCT) is more accurate than conventional catheter angiography for detecting a dangerous congenital heart abnormality that could cause sudden death, according to research by a Saint Louis University radiologist published last month in Catheterization and Cardiovascular Interventions: Journal of the Society for Cardiovascular Angiography and Interventions.

10 Oct 2005

Obese Zucker rat model shares the symptoms of obesity with a growing number of Americans

A mutant rat that mimics a 400-pound human is helping scientists understand early vascular changes that make walking a pain for more than 2 million Americans.

9 Oct 2005

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Anti-angiogenic agents have been successful in the clinic for blocking the growth of solid tumors. However, these agents used in combination with chemotherapy have improved the survival of patients with cancers by only several months.

9 Oct 2005

Vascular News and Research

Urban Britain is a recipe for heart disease

Chlamydia pneumoniae may cause vision problems

Ultrasound to view heart's interior in three dimensions

Important breakthrough in developing the drugs of the future

Paclitaxel may help treat scleroderma

Discovery of signaling mechanism may help prevent metastatic melanoma

First study to confirm the benefit of anti-angiogenic therapy in patients with breast cancer

Two competing drug-eluting stents work equally well

How cells use very slow biological flows to signal and organize

Scientists gain better understanding of how repetitive stretching of endothelial cells that line arteries can make them healthy and resistant to vascular diseases

Nitric oxide may help sickle cell patients

Mixed carbon nanotubes and standard urban particulates suggests a risk of thrombosis from airborne pollution

Yeast cells help show how GSAO (glutathionarsenoxide) angiogenesis inhibitor drug works

Treating four or more brain tumors in a single radiosurgery session resulted in improved survival

Moderate drinking has effects on blood coagulation, primarily as a "blood thinner"

Erectile dysfunction may be a sign that coronary artery disease is developing

Obesity linked to dementia and Alzheimer's disease

Electron-beam computed tomography - a more accurate replacement for coronary catheterizations

Obese Zucker rat model shares the symptoms of obesity with a growing number of Americans

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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