Sildenafil citrate, sold as Viagra, Revatio and under various other trade names, is a drug used to treat erectile dysfunction and pulmonary arterial hypertension (PAH). It was developed and is being marketed by the pharmaceutical company Pfizer. It acts by inhibiting cGMP specific phosphodiesterase type 5, an enzyme that regulates blood flow in the penis. Since becoming available in 1998, sildenafil has been the prime treatment for erectile dysfunction; its primary competitors on the market are tadalafil (Cialis) and vardenafil (Levitra). It is frequently called the 'blue pill'.
A new study published in the British Journal of Anaesthesia aimed to determine whether sildenafil could improve gaseous exchange in patients with COVID-19 ARDS with pulmonary hypertension, RV dysfunction, or both.
In March 2020, Dr. Joseph Vinetz left the contemplative world of his Yale University infectious-disease laboratory and plunged into the covid ward at Yale New Haven Hospital, joining an army of health care workers who struggled to treat the deadly viral disease.
Sildenafil, the generic version of the drug known as Viagra, could be the long-waited remedy for a group of dogs with a rare disorder called megaesophagus.
A new study, published today in Alzheimer's & Dementia, tested whether tadalafil, a drug closely related to Viagra, may be effective in treating people with vascular dementia.
Researchers at Johns Hopkins Medicine have found that a drug first developed to treat Alzheimer's disease, schizophrenia and sickle cell disease reduces obesity and fatty liver in mice and improves their heart function — without changes in food intake or daily activity.
Researchers at Albert Einstein College of Medicine have developed a topical drug that regenerates and restores the function of erectile nerves damaged by radical prostatectomy, the most common treatment for localized prostate cancer.
Many marketing studies have examined the impact of direct-to-consumer advertising of pharmaceuticals on sales and market shares. But in a new study, a researcher from The University of Texas at Dallas wanted to know whether drug advertising might have some unintended, population-level health consequences.
A new study from Lund University and Region Skåne in Sweden indicates that potency-enhancing PDE5 inhibitor drugs have an anti-cancer potential with the ability to improve the prognosis in patients with colorectal cancer.
Scientists report a change in why men seek help for sexual problems, with fewer men complaining about impotence (erectile dysfunction) and premature ejaculation, and more men, especially younger men, complaining about low sexual desire and curvature of the penis (Peyronie's disease).
Researchers discover what's behind nature's perhaps largest erection - which is not that big PLANT BIOLOGY.
Dr. Sudeep Taksali, an orthopedic surgeon, became worried that his 8-year-old daughter had already grown taller than his 12-year-old son. And sometimes she had an attitude more befitting a teenager. Something seemed wrong.
Package labels for Viagra, Cialis, and other erectile dysfunction drugs should inform patients that ED is a sign of potentially fatal artery disease, according to a petition the Physicians Committee for Responsible Medicine filed with the Food and Drug Administration on Feb. 10. Between 18 and 30 million men in the United States have ED.
In a new study scientists have reported that Sildenafil or Viagra pills used for erectile dysfunction could lead to longer lasting visual disturbances than known before. The study titled, “Ocular Side Effects of Sildenafil That Persist Beyond 24 h—A Case Series,” was published in the latest issue of the journal Frontiers in Neurology.
University of Manchester scientists investigating a possible treatment for fetal growth restriction, a condition in which babies grow poorly in the womb, have urged further caution on the use of Viagra.
The combination of two clinically approved drugs--Viagra and Plerixafor--rapidly and efficiently mobilizes blood stem cells from the bone marrow into the bloodstream in mice, researchers report October 10th in the journal Stem Cell Reports.
There's a perception that surgery to treat prostate cancer will spell the end of a man's sex life.
Young gay and bisexual men are frequent users of alkyl nitrites, or poppers, but few show signs of addiction, risky consumption habits or other psychosocial problems, a study shows.
Scientists from the University of Sheffield are part of an international collaboration to develop a new class of drugs to treat a common genetic kidney disease which is a major cause of kidney failure.
By age 50, nearly half of men experience some degree of erectile dysfunction. Advertisements for medications treating the condition have been all over mainstream media for years.
Viagra (sildenafil citrate), known for improving erectile dysfunction (ED), also effectively treats the prostate and lower urinary tract symptoms (LUTS) associated with prostate enlargement that often occur with ED, a Northwestern University study has found.