Viral Disease News and Research

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New insight into autoimmune disease

The immune system is a complex and powerful weapon that provides protection against bacteria and viruses that, if left unchecked, would wreak havoc throughout the human body.

21 Jun 2005

Protocol used to treat the first known survivor of rabies without prior vaccination published

The protocol used to treat the first known survivor of rabies without prior vaccination is published in the June 16, 2005, issue of the New England Journal of Medicine. It is hoped that this approach can be replicated, tested, and provide a guide for treating this fatal condition, especially in parts of the world where the incidence of rabies is rampant.

15 Jun 2005

When in Russia, drink vodka

Drinking the local beer has landed some 461 Russians in hospital with Hepatitis A and Tver Governor Dmitry Zelenin fully expects that number to rise over the next few days.

13 Jun 2005

Association between chronic cytomegalovirus (CMV) and frailty syndrome

Older women with chronic cytomegalovirus (CMV), a lifelong viral infection, were found to have more than triple the risk of being frail than those who did not have the infection, as reported in the Journal of the American Geriatrics Society. This is the first demonstration to show an association between CMV and frailty syndrome.

9 Jun 2005

Several minute intermediate stage in virus-cell fusion may represent a window of opportunity for drug development

To ignite a life-threatening infection in the body, a virus such as HIV invades body cells by first merging, or fusing, with the cell's outer membrane. Once inside the cell, the invading microbe's genetic material takes over, turning the 'host' cell into a factory to produce more copies of the virus, which then spill out to invade other cells in the body.

8 Jun 2005

Cranberry juice may be effective in treating a number of gastrointestinal viruses

Cranberry juice, long considered a home remedy for urinary tract infections, may also be effective against a number of gastrointestinal viruses according to researchers from St. Francis College in Brooklyn, New York. They report their findings today at the 105th General Meeting of the American Society for Microbiology.

6 Jun 2005

West Nile virus more of a threat than previously thought

West Nile has traditionally only been considered a serious problem for the elderly and frail, and more of a nuisance illness for everyone else. But a surprising number of patients show the virus is more threatening than widely believed.

31 May 2005

Measuring hormone procalcitonin cuts antibiotic use in half in pneumonia patients

Measuring a hormone in the blood can help doctors greatly reduce the number of days pneumonia patients have to take antibiotics to cure their infection, according to a study to be presented at the American Thoracic Society International Conference.

25 May 2005

Virus from rodents kills three transplant recipients

Three transplant patients have died as a result of receiving an organ from a donor who had unknowingly been infected with a common rodent virus. A fourth patient who received a kidney from the organ donor is recovering.

24 May 2005

Discovery of a fundamental new route into cells may lead to new methods of drug delivery

Researchers from The University of Queensland’s Institute for Molecular Bioscience (IMB), and the Centre for Microscopy and Microanalysis used electron microscopy to uncover new structures, 100,000th of a mm in size, which are involved in the very first step of particle and nutrient uptake into cells.

10 May 2005

Small number of genes can predict response to chronic hepatitis C therapy

For the first time, physicians at University Health Network and University of Toronto have identified a small subset of genes that can predict whether a patient with chronic Hepatitis C will be able to respond to current treatments.

2 May 2005

P12 protein influences key cell-signaling pathway

New research shows that a protein produced by a cancer-causing virus influences a key signaling pathway in the immune cells that the virus infects. This stimulates the cells to divide, helping the virus spread through the body.

26 Apr 2005

Mumps jabs may run out in Ireland

GPs in Northern Ireland are warning that following a mumps outbreak among teenagers and young adults, supplies of the MMR vaccine in Northern Ireland could be running out. Family doctors have been asked to return any unused supplies so these can be re-distributed.

12 Apr 2005

Treatment of bronchiolitis in children varies widely and often results in unnecessary tests and antibiotics

Considerable differences exist in the treatment of bronchiolitis at children's hospitals across the United States, according to a study from Children's Hospital and Regional Medical Center in Seattle published in the April 1 issue of Pediatrics.

4 Apr 2005

Tarvacin shows significant anti-viral activity

Peregrine Pharmaceuticals today announced that there will be two presentations, April 4 and 6, at the American Association of Immunologists (AAI) annual meeting in San Diego, California, indicating the anti-viral potential of its Tarvacin antibody. Dr. Melina Soares of The University of Texas Southwestern Medical Center at Dallas will present pre-clinical data titled "Targeting inside-out phospholipids on viruses in a guinea pig model of Lassa fever."

4 Apr 2005

AIDS virus initially more destructive than first thought

The AIDS virus destroys more than half of the immune cells that might recognize and help fight it, within days of infection according to US researchers, and this revelation might necessitate a re-evaluation of how the deadly infection should be tackled.

28 Mar 2005

Research tool for turning off genes may eventually have therapeutic application

A research team based at Massachusetts General Hospital (MGH) has identified 80 new genes essential to the process of RNA interference (RNAi), a powerful new research tool for inactivating genes in plants or animals.

28 Mar 2005

Intervention with once-daily budesonide reduces long-term risk and frequency of severe asthma-related events

New data indicated that earlier intervention with once-daily budesonide, an inhaled corticosteroid delivered by dry powder inhaler to children with mild persistent asthma, significantly reduced the long-term risk and frequency of severe asthma-related events as well as the need for other inhaled medication.

21 Mar 2005

Study reveals how brain's immune system fights viral encephalitis

The findings, published as the cover study in the latest issue of Virology, show that proteins in neurons fight the virus at multiple stages - by preventing the formation of viral RNA and proteins, and blocking the virus' release, which could infect other cells in the brain.

16 Mar 2005

£800,000 to boost research into fighting viruses

A team of University of Glasgow scientists have received a grant of £800,000 from the Wellcome Trust to research a mechanism that blocks a critical step in the replication cycle of retroviruses. In the long term, the research could lead to the design of new therapeutic strategies or drugs against retroviruses, which cause diseases such as AIDS and certain leukemias.

14 Mar 2005