Whole Genome Sequencing News and Research

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Novel genome-analysis strategy to speed search for gene-disease links

University of Washington (UW) researchers have successfully developed a novel genome-analysis strategy for more rapid, lower cost discovery of possible gene-disease links. By saving time and lowering expenses, the approach makes it feasible for scientists to search for disease-causing genes in people with the same inherited disorder but without any family ties to each other.

18 Aug 2009

Scientists develop whole-genome sequencing approach to mapping mutations in fruit flies

The Stowers Institute's Hawley Lab and Molecular Biology Facility have developed a "whole-genome sequencing approach" to mapping mutations in fruit flies.

5 May 2009

Impending crisis in provision of histopathology expertise for mouse functional genomics

The generation of new mouse models of human disease is accelerating rapidly due to the completion of whole-genome sequencing efforts and technological advances in the manipulation of the mouse genome.

18 Nov 2008

Can IT fuel the race to the $1,000 human genome?

Ever wonder if you have a genetic disposition to a certain disease, or why a medicine works for your friend, but not for you?

21 Apr 2008

Researchers examine human embryonic stem cell genome

Stem cell researchers from UCLA used a high resolution technique to examine the genome, or total DNA content, of a pair of human embryonic stem cell lines and found that while both lines could form neurons, the lines had differences in the numbers of certain genes that could control such things as individual traits and disease susceptibility.

31 Mar 2008

Toward the ethical treatment of whole genome research participants

Recent technological developments have made it possible for scientists to sequence an entire human genome, but these advances may be a mixed blessing.

25 Mar 2008

Indian bug is the ancestor of Crohn's disease pathogen

An Indian team of researchers led by Seyed E. Hasnain of the Institute of Life Sciences (ILS), University of Hyderabad, India has found that a seemingly unknown mycobacterial organism Mycobacterium indicus pranii (MIP) could be the earliest ancestor of the 'generalist' branch of mycobacterial pathogens.

3 Oct 2007

BioNanomatrix and Complete Genomics form joint venture after NIST grant awarded

BioNanomatrix, Inc. and Complete Genomics Inc. (CGI) have announced that they have formed a joint venture that has received an $8.8 million grant award from the U.S. National Institute of Standards and Technology Advanced Technology Program (NIST-ATP) to develop a system capable of sequencing the entire human genome in eight hours at a cost of less than $100

29 Sep 2007

Significant step forward in the genome era

In what promises to be a significant step forward in the genome era, the National Human Genome Research Institute (NHGRI) today announced plans to devote a portion of its large-scale sequencing capacity to efforts aimed at identifying the genetic roots of specific diseases that have long eluded gene hunters.

17 Oct 2005

Study on first new potential drug for tuberculosis in 40 years

454 Life Sciences, a majority-owned subsidiary of CuraGen Corporation, announced today that its proprietary whole genome sequencing technology was used by scientists at Johnson & Johnson Pharmaceutical Research & Development L.L.C. (J&JPRD) to help understand the basis of tuberculosis drug resistance.

20 Dec 2004

Grant to develop high speed DNA sequence reader

Sequencing of the human genome is one of the major scientific advances of our time. But with 3 billion base pairs, initial sequencing of the human genome took 11 years and cost $1 billion to complete in 2002. Today, it costs up to $50 million to sequence 3 billion base pairs.

1 Nov 2004

More efficient method to sequence the human genome

Researchers at Baylor College of Medicine have been tabbed to find a more efficient method to sequence the human genome.

18 Oct 2004

Completion of the sequencing of human chromosome 19

The United States Department of Energy (DOE) Joint Genome Institute (JGI) and Stanford University report today the completion of the sequencing of human chromosome 19, the most gene-rich of all the human chromosomes. This achievement is described in the April 1, 2004 edition of the journal Nature.

7 Apr 2004