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Discovery of major new treatment target in diseased arteries

Removing a single protein prevents early damage in blood vessels from triggering a later-stage, frequently lethal complication of atherosclerosis, according to research published online today in the journal Nature Medicine. By eliminating the gene for a signaling protein called cyclophilin A (CypA) from a strain of mice, researchers were able to provide complete protection against abdominal aortic aneurysm (AAA).

11 May 2009

FDA approves Avastin (bevacizumab) for treatment of glioblastoma multiforme

The U.S. Food and Drug Administration recently approved Avastin (bevacizumab) to treat patients with glioblastoma multiforme (GBM) when this form of brain cancer continues to progress following standard therapy.

7 May 2009

Stem cell focus for inflammatory bowel disease wound healing

Scientists at The University of Nottingham are investigating whether stem cell markers could have a role to play in speeding up wound healing in patients suffering from inflammatory bowel disease (IBD).

30 Apr 2009

Mites on hissing coackroach may benefit humans with allergies

Tiny mites living on the surface of Madagascar hissing cockroaches help decrease the presence of a variety of molds on the cockroaches' bodies, potentially reducing allergic responses among humans who handle the popular insects, according to new research.

29 Apr 2009

Collagen bioscaffolds used to treat diabetic ulcers, save limbs

San Diego surgeons report that they have been successfully utilizing a collagen bioscaffold material developed by Irvine-based Pegasus Biologics, Inc. to complement soft tissue repair and regeneration among high risk wound patients.

22 Apr 2009

Human foetal stem cells can effectively be used to treat back leg ischaemic ulcers

Treatment of chronic wounds is a continuing clinical problem and socio-economic burden with diabetic foot ulcers alone costing the NHS £300 million a year.

20 Apr 2009

Hand-assisted laparoscopic surgery benefits colorectal patients

Despite rapid strides in minimally invasive surgical techniques -- most notably, laparoscopy -- traditional open surgery remains the most common surgical option across the United States for people with diseases of the rectum and colon.

15 Apr 2009

Study finds multidrug-resistant gram-negative bacteria high in long-term care

The prevalence of a certain form of drug-resistant bacteria, called multidrug-resistant gram-negative (MDRGN) organisms, far surpassed that of two other common antimicrobial-resistant infections in long-term care facilities, according to a study conducted by researchers at Hebrew SeniorLife's Institute for Aging Research.

12 Apr 2009

Large safety gaps identified between top and bottom performing hospitals

The 2009 HealthGrades Patient Safety Excellence Award™ recipients were identified in a report issued today by the leading independent healthcare ratings organization.

8 Apr 2009

Stem cells from bone marrow used to grow new blood vessels

Research led by David Hess of the Robarts Research Institute at The University of Western Ontario has identified how to use selected stem cells from bone marrow to grow new blood vessels to treat diseases such as peripheral artery disease.

6 Apr 2009

New York Medicaid adds topical oxygen wound therapy benefit

Beneficiaries of the New York Medicaid program have a new option to choose when dealing with chronic wounds.

1 Apr 2009

Protein ferritin in blood may hold key to stopping tumor growth in cancer patients

A recent discovery by researchers at Wake Forest University School of Medicine could clear the way for a new drug that inhibits tumor growth in cancer patients and could potentially help in the healing of wounds.

1 Apr 2009

A magic bullet for superbugs

Attaching an antimicrobial drug, which is activated by light, to a peptide that binds to bacteria and stops them making toxins, produced a "magic bullet" that was highly effective at killing the superbug, methicillin-resistant Staphylococcus aureus (MRSA).

1 Apr 2009

Is transforming growth factor-beta involved in intestinal wound healing?

Migration of colonic lamina propria fibroblasts (CLPF) plays an important role during the progression of fibrosis and fistulae in Crohn's disease.

30 Mar 2009

War wounded at risk for superbugs

Soldiers who survive severe injuries on battlefields such as those in Iraq and Afghanistan can be at risk from developing infections of their wounds with multidrug resistant bacteria.

30 Mar 2009

RegeneRx reports phase II venous stasis trial results

Regenerx Biopharmaceuticals Inc. has announced the results of its Phase II clinical trial evaluating the safety and wound-healing efficacy of RGN-137 for the treatment of patients with venous stasis ulcers.

29 Mar 2009

Discovery of a protein link to wound healing

Diabetes and eczema may appear to be two completely unrelated diseases.

24 Mar 2009

Time (and PPAR-beta/delta) heals all wounds

Mammalian skin requires constant maintenance, but how do skin cells know when to proliferate and at what rate?

23 Mar 2009

Coatings that kill superbugs

Researchers at the University of Bath are to be part of a 3 million Euros Europe-wide research collaboration to pioneer research into safer, more effective anti-bacterial plastics and coatings that can be used in items such as food packaging, medical devices to wound dressings, and nappies.

20 Mar 2009

Research yields potential target for cancer, wound healing and fibrosis

Research conducted by Allison Berrier, PhD, Assistant Professor of Oral and Craniofacial Biology at the LSU Health Sciences Center New Orleans School of Dentistry, and colleagues, provides insights that may help scientists design novel approaches to control wound healing and fight diseases such as cancer and fibrosis.

20 Mar 2009