Xenograft News and Research

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Xenograft are the cells of one species transplanted to another species.
Advancing CAR T-cell therapy for treatment of solid tumors

Advancing CAR T-cell therapy for treatment of solid tumors

Targeting PI3Kβ alone and with combination therapy in PTEN-deficient tumors

Targeting PI3Kβ alone and with combination therapy in PTEN-deficient tumors

New discovery could lead to better strategies for preventing breast cancer metastasis

New discovery could lead to better strategies for preventing breast cancer metastasis

Study provides new insight into neurofibromin-deficient ER+ breast cancer

Study provides new insight into neurofibromin-deficient ER+ breast cancer

P53-deficient oral cancers recruit and reprogram nerves to fuel tumor growth

P53-deficient oral cancers recruit and reprogram nerves to fuel tumor growth

Researchers develop first non-invasive way to monitor oxygen in tumors during radiation therapy

Researchers develop first non-invasive way to monitor oxygen in tumors during radiation therapy

Study may provide novel targetable mechanisms of therapeutic resistance to anti-VEGF therapies

Study may provide novel targetable mechanisms of therapeutic resistance to anti-VEGF therapies

Daily aspirin use may help prevent colorectal cancer

Daily aspirin use may help prevent colorectal cancer

Mount Sinai awarded more than $10 million in federal funding for research on glioblastoma

Mount Sinai awarded more than $10 million in federal funding for research on glioblastoma

Catastrophic macropinocytosis may aid in cancer treatment

Catastrophic macropinocytosis may aid in cancer treatment

Novel and targeted cellular product causes cell death in non-Hodgkin lymphoma models

Novel and targeted cellular product causes cell death in non-Hodgkin lymphoma models

Study: Calcium signaling can help address drug resistance to non-Hodgkin lymphoma

Study: Calcium signaling can help address drug resistance to non-Hodgkin lymphoma

Apoptosis protein API-5 more markedly expressed in chemoresistant triple-negative breast cancer

Apoptosis protein API-5 more markedly expressed in chemoresistant triple-negative breast cancer

Clinical analysis reveals high expression of apoptosis protein in chemoresistant TNBC

Clinical analysis reveals high expression of apoptosis protein in chemoresistant TNBC

New method may offer effective treatment for pancreatic cancer with fewer side effects

New method may offer effective treatment for pancreatic cancer with fewer side effects

Yale scientists build powerful genomic research platform to study cervical cancer

Yale scientists build powerful genomic research platform to study cervical cancer

Live-cell, genetically engineered pig skin used for temporary closure of a burn wound

Live-cell, genetically engineered pig skin used for temporary closure of a burn wound

Repurposed quinacrine can reduce tumor burden in mice bearing HNSCC xenograft tumors

Repurposed quinacrine can reduce tumor burden in mice bearing HNSCC xenograft tumors

Targeting HDAC2 reduces MDM2 expression and has anti-tumor effects in dedifferentiated liposarcoma

Targeting HDAC2 reduces MDM2 expression and has anti-tumor effects in dedifferentiated liposarcoma

Novel viral vector improves gene therapy for sickle cell disease

Novel viral vector improves gene therapy for sickle cell disease