Yellow Fever News and Research

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Yellow fever virus, a flavivirus, is transmitted to humans through the bite of infected mosquitoes. Illness ranges in severity from a self-limited febrile illness to severe hepatitis and hemorrhagic fever. Yellow fever disease is diagnosed based on symptoms, physical findings, laboratory testing, and the possibility of exposure to infected mosquitoes. There is no specific treatment for yellow fever; care is based on symptoms. Steps to prevent yellow fever include use of insect repellent, protective clothing, and vaccination. Yellow fever occurs in tropical regions of Africa and in parts of South America. Yellow fever is a very rare cause of illness in U.S. travelers. The last epidemic of yellow fever in North America occurred in New Orleans in 1905.

Virginia Tech researchers receive $2.7 million grant to study mosquito's biological timing

Mosquitoes may be small, but they are a formidable foe. Not only can they smell over 400 chemicals that we emit and detect the carbon dioxide we breathe out, but they can even adapt their daily behavior in response to our own.

16 Jul 2021

23 million children missed out on basic vaccines in 2020 due to COVID-19, new data shows

23 million children missed out on basic vaccines through routine immunization services in 2020 – 3.7 million more than in 2019 - according to official data published today by WHO and UNICEF.

15 Jul 2021

Natural compound 'pheophorbide a' demonstrates robust antiviral activity against SARS-CoV-2 in vitro

A team of scientists from France has recently demonstrated photosensitive antiviral activity of the natural compound pheophorbide a (Pba) against a broad range of enveloped viruses, including coronaviruses.

12 Jul 2021

New genetic approach offers clues to the regulation of Wolbachia proliferation

Despite having been formalized as a species in 1936, Wolbachia pipientis remains an elusive microbe. The reason why relates to the relationship it establishes with its hosts.

8 Jul 2021

Clinical observations show acute myocarditis developed after mRNA COVID-19 vaccination

Four patients suffering from acute myocarditis after mRNA COVID-19 vaccination suggests that further investigation is needed.

29 Jun 2021

The role of natural killer cells in fight against viral infections including SARS-CoV-2

In an effort to further understand the role of NK cells in combatting COVID-19, a group of researchers explored NK cells in acute viral infections, citing flavivirus and influenza virus infections as examples.

17 Jun 2021

Scientists use an original approach to resolve the 3D structure of flaviviruses

In a recent study, Australian scientists used an original approach to resolve the 3D structure of flaviviruses with an unprecedented level of detail, identifying small molecules known as 'pocket factors' as new therapeutic targets.

1 Jun 2021

Zoonotic and vector-borne emerging tropical diseases pose a constant threat

A recent article published in the journal Frontiers in Tropical Diseases assessed the threat of emerging zoonotic and vector-borne tropical diseases.

26 May 2021

Novel broad-spectrum antiviral compounds effective against Zika and SARS-CoV-2

A research team at the University of Alberta, Canada, led by Dr. Daniel Limonta, has described two novel molecules with broad antiviral properties that are effective against a range of virus types, including SARS-CoV-2.

21 May 2021

Animal and insect invasions could shed light on COVID-19 transmission

Invasions by alien insect and animal species have much in common with outbreaks of infectious diseases and could tell us a great deal about how pandemics spread, according to a research paper published today.

19 May 2021

Natural products a rich source for novel antiviral compounds

In a recent review in the journal Viruses, researchers look at natural products that can be identified as potential alternative antiviral agents. The reviewers discussed the antiviral activities of several natural products towards DNA and RNA viruses with an analytical approach. The researchers detailed the cellular/viral targets of the active molecules and their impact on the infection and viral replication cycle.

10 May 2021

Mosquito protein study could lead to therapeutics against deadly viruses

The mosquito protein AEG12 strongly inhibits the family of viruses that cause yellow fever, dengue, West Nile, and Zika and weakly inhibits coronaviruses, according to scientists at the National Institutes of Health (NIH) and their collaborators.

10 Mar 2021

Coronavirus deranges the immune system in complex and deadly ways

There's a reason soldiers go through basic training before heading into combat: Without careful instruction, green recruits armed with powerful weapons could be as dangerous to one another as to the enemy.

4 Mar 2021

Research shows how antibodies attach to and block Zika virus

The Zika outbreak of 2015 and 2016 are having lasting impacts on children whose mothers became infected with the virus while they were pregnant.

25 Feb 2021

A machine-learning approach to track how yellow fever mosquito moves through the environment

The yellow fever mosquito (Aedes aegypti) is a main vector of deadly diseases like dengue fever, chikungunya, and the Zika virus, which result in hundreds of thousands of deaths worldwide each year.

24 Feb 2021

Researchers develop models to predict epidemics of yellow fever, other mosquito-borne diseases

Yellow fever was the first human disease to have a licensed vaccine and has long been considered important to an understanding of how epidemics happen and should be combated.

23 Feb 2021

International health organizations establish global Ebola vaccine stockpile

The four leading international health and humanitarian organizations announced today the establishment of a global Ebola vaccine stockpile to ensure outbreak response.

18 Jan 2021

New genomics resource details the small RNA transcriptomes of four mosquito species

Researchers from Boston University School of Medicine provide a new genomics resource that details the small RNA transcriptomes (gene expression) of four bio-medically important mosquito species.

13 Jan 2021

Is one-dose COVID-19 vaccination better than two?

A recent study published on the preprint server medRxiv in December 2020 reflects on the possibility of using a single-dose vaccine regimen to accomplish large-scale vaccination as early as possible.

6 Jan 2021

Asian tiger mosquito does not pose a major risk for Zika virus epidemics

The Asian tiger mosquito does not pose a major risk for Zika virus epidemics, according to a study published December 31 in the open-access journal PLOS Pathogens by Albin Fontaine of the Institut de Recherche Biomédicale des Armées, and colleagues.

4 Jan 2021