Yellow Fever News and Research

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Yellow fever virus, a flavivirus, is transmitted to humans through the bite of infected mosquitoes. Illness ranges in severity from a self-limited febrile illness to severe hepatitis and hemorrhagic fever. Yellow fever disease is diagnosed based on symptoms, physical findings, laboratory testing, and the possibility of exposure to infected mosquitoes. There is no specific treatment for yellow fever; care is based on symptoms. Steps to prevent yellow fever include use of insect repellent, protective clothing, and vaccination. Yellow fever occurs in tropical regions of Africa and in parts of South America. Yellow fever is a very rare cause of illness in U.S. travelers. The last epidemic of yellow fever in North America occurred in New Orleans in 1905.

Mosquito-borne viral outbreaks pose serious issues in West Africa

In a new study, researchers from the Colorado School of Public Health at the University of Colorado Anschutz Medical Campus call attention to the emergence of mosquito-borne viral outbreaks in West Africa, such as dengue (DENV), chikungunya (CHIKV) and Zika (ZIKV) viruses.

19 May 2020

Specific immune cells induced by vaccination are early indicators of vaccine efficacy

Ludwig-Maximilians-Universität in Munich researchers have shown that a specific class of immune cells in the blood induced by vaccination is an earlier indicator of vaccine efficacy than conventional tests for neutralizing antibodies.

15 May 2020

New clinical trial to investigate the efficacy of ivermectin against COVID-19

Clínica Universidad de Navarra and the Barcelona Institute for Global Health (ISGlobal), a centre supported by the "la Caixa" Foundation, have launched a clinical trial to investigate the efficacy of ivermectin against COVID-19.

14 May 2020

COVID-19 progression linked to B cell activation

The disease course of COVID-19 is diverse, ranging from asymptomatic to fatal respiratory failure. Scientists have been working to uncover the immunological reasons behind this heterogeneity. A recent study on B cells, published on the preprint server medRxiv in April 2020, shows that extrafollicular B cells could be a marker of severe infection in the early stages, predicting the need for earlier immunomodulatory therapy.

4 May 2020

Always the bridesmaid, public health rarely spotlighted until it’s too late

The U.S. is in the midst of both a public health crisis and a health care crisis. Yet most people aren't aware these are two distinct things. And the response for each is going to be crucial.

4 May 2020

Study sheds new light on the body's initial response to DENV infection

A study led by scientists at the Walter Reed Army Institute of Research sheds new light on the body's initial response to dengue virus (DENV) infection, describing the molecular diversity and specificity of the antibody response.

4 May 2020

Research provides insights into how Zika virus can spread through sexual contact

Zika virus is capable of replicating and spreading infectious particles within the outermost cells lining the vaginal tract, according to new research. The findings provide the first molecular-level insights into how the virus can move from person to person through sexual contact.

27 Apr 2020

Resurgence of measles or polio outbreaks likely to happen, experts warn

Interruptions to vaccination programmes caused by the COVID-19 pandemic could result in new waves of measles or polio outbreaks, health experts warn.

24 Apr 2020

Emergex partners with George Mason University for highly pathogenic RNA virus studies

Emergex Vaccines Holding Limited, a biotechnology company developing CD8+ priming set-point vaccines to prevent serious infectious diseases, today announced that it has entered into an agreement with the George Mason University, based in Virginia, in the United States.

22 Apr 2020

Scientists estimate fatality ratio across full spectrum of COVID-19 disease

A team of researchers from Imperial College London has conducted a study aimed at calculating a reasonably accurate case fatality ratio and infection fatality ratio, which is based on Chinese data as well as international reports. The research is published on the pre-print server MedRxiv.

19 Apr 2020

Study identifies two new viruses in Brazilian patients with suspected dengue

Two new species of viruses have been identified in blood samples taken from patients in Brazil's northern region who had similar symptoms to those of dengue or Zika, such as high fever, severe headache, rash and red skin spots.

17 Apr 2020

Study clears potential barrier to controlling mosquito-borne diseases

New research from entomologists at UC Davis clears a potential obstacle to using CRISPR-Cas9 "gene drive" technology to control mosquito-borne diseases such as malaria, dengue fever, yellow fever and Zika.

17 Apr 2020

Stuttering DNA controls development of mosquito embryos

All organisms have DNA, the genetic material that provides a blueprint for life. The long double-helix-shaped DNA molecules in the body's cells are first translated into RNA molecules and then translated into proteins that ensure the functioning of the cell and the entire organism.

12 Apr 2020

Is the Bay Area’s ‘unprecedented’ lockdown the first of many?

Life came to a grinding halt for millions of San Francisco Bay Area residents as the most stringent isolation orders in the country took effect Tuesday.

17 Mar 2020

Efforts to correct misperceptions about Zika virus may not be as effective as believed

When disease epidemics and outbreaks occur, conspiracy theories often emerge that compete with the information provided by public health officials.

28 Feb 2020

Experimental vaccine could be effective against both Zika and Dengue

Walter Reed army institute of research has shown that a new vaccine against the Zika virus could be effective against both Zika and dengue virus. The study titled, “Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue experienced donor,” in the latest issue of the journal Nature Medicine.

3 Feb 2020

Study explains equal attraction of mosquitoes to flowers and humans

A new study published online on December 23 in the Proceedings of the National Academy of Sciences reports the discovery of the basis on which mosquitoes are drawn towards a type of orchid of which they are inordinately fond, resulting in its pollination.

22 Jan 2020

Genetically engineered mosquitoes halt Dengue spread

A new study published in the journal PLOS Pathogens in January 2020 reports the development of mosquitoes that have been genetically modified to resist infection by several types of the dengue virus. This is the first time ever that all types of the virus have been targeted by the engineering of the mosquito DNA. Covering all virus types is essential to achieve proper disease control.

16 Jan 2020

Researchers refine history and origins of common pathogens in human populations

An Italian research team has refined the history and origins of two extremely common pathogens in human populations, herpes simplex virus type 1 and type 2.

13 Jan 2020

Scientists unveil how Zika virus replicates

The World Health Organization (WHO) declared the Zika virus infection a global threat during the peak of its outbreak in 2016. Since then, scientists and health experts raced to understand the virus better to develop novel and effective vaccines and treatments for the disease. Now, a team of researchers in China revealed how a protein in the virus reshapes its host to boost viral replication.

23 Dec 2019