Zoledronate News and Research

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Zoledronate is a drug used to treat patients with hypercalcemia (high blood levels of calcium) caused by cancer. It is also used together with other drugs to treat multiple myeloma and to prevent bone fractures and reduce bone pain in people who have cancer that has spread to the bone. It is a type of bisphosphonate. Also called zoledronic acid and Zometa.

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

A prospective path for allogeneic cellular immunotherapies.

13 Nov 2023

Some of the main osteoporosis treatments could have a protective effect against COVID-19

Some of the principal treatments for osteoporosis, denosumab, zoledronate and calcium, could have a protective effect against COVID-19 in patients who take them, specifically a 30 to 40% reduction in the rate of infection, according to the results of a joint study by Hospital del Mar, the Hospital del Mar Medical Research Institute (IMIM), Pompeu Fabra University and the Pere Virgili Health Park.

3 Nov 2020

Oxytocin can aid in the control and prevention of osteoporosis

Oxytocin, produced by the hypothalamus and sometimes known as the "love hormone" for its involvement in pair bonding and orgasm, can be a strong ally in the control and prevention of osteoporosis, according to a study by scientists at São Paulo State University in Brazil.

10 Aug 2020

Are fruit fly 'avatars' the next step in personalized medicine?

Researchers have created fruit fly “avatars” that have helped to guide treatment for a man who had terminal colon cancer.

24 May 2019

USC researchers report breakthrough to prevent osteonecrosis of the jaw

USC researchers and collaborators report a breakthrough to prevent damage to the jaw, a side effect suffered by some people undergoing treatment for cancer or osteoporosis.

11 Apr 2019

CRPS rank higher on pain scales than childbirth, cancer, amputation

Imagine pain in an arm or leg so intense that the sufferer would rather undergo an amputation than put up with it any longer. For those with complex regional pain syndrome (CRPS), this is not just a hypothetical nightmare—it is reality.

25 Mar 2016

Zoledronate drug can protect stem cells from ageing

Stem cells can be protected from the effects of ageing by a drug currently used to treat patients with osteoporosis, a breakthrough study has found.

17 Dec 2015

Drugs used to treat osteoporosis appear to prevent cell membrane repair

A class of drugs widely used to treat osteoporosis appears to impede a cell's ability to repair a protective outer membrane that helps determine what enters and exits, researchers report.

15 Apr 2014

Predictors of bone metastasis, skeletal events in lung cancer identified

Researchers have identified a range of factors that are associated with the likelihood that a patient with advanced lung cancer will develop bone metastases or skeletal-related events.

20 Feb 2014

Bisphosphonate zoledronate treatment not effective in women with chemoresistant breast cancer

Treatment with the bisphosphonate zoledronate did not improve outcomes for women with chemoresistant breast cancer, according to initial results of a phase III clinical trial presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.

14 Dec 2013

Osteoporosis drug could provide effective pain relief to patients with osteoarthritis

St George's, University of London research has found that a drug normally given to osteoporosis sufferers could provide effective pain relief to patients with knee and hip osteoarthritis.

6 Sep 2013

Chemically altered osteoporosis drug may fight malaria

A chemically altered osteoporosis drug may be useful in fighting malaria, researchers report in a new study. Unlike similar compounds tested against other parasitic protozoa, the drug readily crosses into the red blood cells of malaria-infected mice and kills the malaria parasite. The drug works at very low concentrations with no observed toxicity to the mouse.

27 Feb 2012

$Zoledronate at lower dose effective in reducing risk of osteoporotic fractures$

Zoledronate News and Research

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

Some of the main osteoporosis treatments could have a protective effect against COVID-19

Oxytocin can aid in the control and prevention of osteoporosis

Are fruit fly 'avatars' the next step in personalized medicine?

USC researchers report breakthrough to prevent osteonecrosis of the jaw

CRPS rank higher on pain scales than childbirth, cancer, amputation

Zoledronate drug can protect stem cells from ageing

Drugs used to treat osteoporosis appear to prevent cell membrane repair

Predictors of bone metastasis, skeletal events in lung cancer identified

Bisphosphonate zoledronate treatment not effective in women with chemoresistant breast cancer

Osteoporosis drug could provide effective pain relief to patients with osteoarthritis

Chemically altered osteoporosis drug may fight malaria

Zoledronate at lower dose effective in reducing risk of osteoporotic fractures

Acceleron presents RAP-661 preclinical data in osteopenic mice at international meeting

New data suggests bisphosphonate drug may play a role in reducing recurrent breast cancer

Amgen's AMG-162 for treatment of osteoporosis will become a blockbuster by 2013

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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