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Selective removal of aging cells represents a new paradigm for treating age-related diseases

A research team, led by Professor Ja Hyoung Ryu from the Department of Chemistry at UNIST, in collaboration with Professor Hyewon Chung from Konkuk University, has achieved a significant breakthrough in the treatment of age-related diseases.

4 Oct 2023

New study reveals BA.2.86 subvariant's surprising dance with antibodies

Researchers examined the antigenicity of the emerging SARS-CoV-2 subvariant BA.2.86, finding that it is not resistant to neutralizing antibodies from previously infected or vaccinated individuals, although it does show increased binding affinity to the ACE-2 receptor. The study highlights the subvariant's sensitivity and resistance to different classes of monoclonal antibodies, offering insights for future treatment and vaccine development.

2 Oct 2023

Groundbreaking discovery reveals how brain proteins can help alleviate DNA replication stress

A team of researchers from the Department of Biological Sciences at UNIST has achieved a significant breakthrough in understanding how brain proteins can help alleviate complications arising from DNA replication stress.

12 Sep 2023

Low-molecular weight human interleukin-1β antagonist discovered

Researchers described the detection of a human interleukin-1β antagonist with low molecular weight that disrupts interactions with the interleukin-1 receptor type I receptor.

11 Sep 2023

Optibrium acquires BioPharmics LLC, expanding its 3D drug design and visualisation offering

Optibrium, a leading developer of software and AI solutions for drug discovery, today announced the acquisition of BioPharmics LLC.

From Optibrium Ltd. 31 Aug 2023

Engineered ACE2 decoy shows promise as COVID-19 treatment

Researchers from Japan demonstrated that an engineered angiotensin-converting enzyme 2 (ACE2) receptor, which showed the potential to remarkably reduce the emergence of resistant virus strains, could successfully exert its therapeutic effect in primates, which may open avenues for the application of the technology for the treatment of humans.

30 Aug 2023

Unlocking ACE2: The enzyme that links COVID-19, heart disease, and diabetes

A recent study in the Journal of Biomedical Science examines the critical role of ACE2, an enzyme involved in blood volume and electrolyte balance, in chronic diseases like cardiovascular conditions, diabetes, and COVID-19. The research suggests that ACE2 could serve as both a disease severity biomarker and a therapeutic target.

28 Aug 2023

A hybrid approach to re-engineer a SARS-CoV-1 neutralizing antibody against SARS-CoV-2

A hybrid approach involving a combination of conventional discovery and antibody repurposing to combat COVID-19.

21 Aug 2023

Deep learning framework DeepAIR could improve understanding of adaptive immunity

Researchers presented a deep learning framework, DeepAIR, to accurately predict adaptive immune receptor (AIR)-antigen binding.

15 Aug 2023

Cryo-EM structures and functions of potent bispecific antibodies against multiple Omicron sublineages

Researchers characterizes the structures and functions of potent bispecific antibodies against multiple Omicron subvariants using Cryo-EM.

3 Aug 2023

New study spotlights effective strategy against COVID-19 variants: the E7 monoclonal antibody

Researchers developed potent monoclonal antibodies from a severe acute respiratory syndrome coronavirus (SARS-CoV) survivor.

1 Aug 2023

Tumor-derived GDF-15 suppresses immunotherapy response

Researchers evaluate the impact of tumor-derived GDF-15 on responses to anti-PD-1 immunotherapy.

26 Jul 2023

Characterizing the concentration and binding affinity of WT–induced antibodies against the Omicron subvariant BA.1

A recent study characterized the concentration and binding affinity of antibodies induced by SARS-CoV-2 WT strain against the Omicron subvariant BA.1.

25 Jul 2023

Difficult transmembrane protein targets for therapeutic antibodies

In this interview, News-Medical talks to Sylvia Xie, product scientist at Sino Biological, about the ongoing emergence of transmembrane proteins as targets for therapeutic antibodies.

From Sino Biological Inc. 12 Jul 2023

Scientists develop breakthrough approach to create artificial allosteric sites in protein complexes

According to a recently published research paper by a team of scientists, a groundbreaking approach has been developed to create artificial allosteric sites (where by binding an effector molecule, activity at the distal active site is regulated) in protein complexes.

6 Jul 2023

binding affinity News and Research

Selective removal of aging cells represents a new paradigm for treating age-related diseases

New study reveals BA.2.86 subvariant's surprising dance with antibodies

Groundbreaking discovery reveals how brain proteins can help alleviate DNA replication stress

Low-molecular weight human interleukin-1β antagonist discovered

Optibrium acquires BioPharmics LLC, expanding its 3D drug design and visualisation offering

Engineered ACE2 decoy shows promise as COVID-19 treatment

Unlocking ACE2: The enzyme that links COVID-19, heart disease, and diabetes

A hybrid approach to re-engineer a SARS-CoV-1 neutralizing antibody against SARS-CoV-2

Deep learning framework DeepAIR could improve understanding of adaptive immunity

Cryo-EM structures and functions of potent bispecific antibodies against multiple Omicron sublineages

New study spotlights effective strategy against COVID-19 variants: the E7 monoclonal antibody

Tumor-derived GDF-15 suppresses immunotherapy response

Characterizing the concentration and binding affinity of WT–induced antibodies against the Omicron subvariant BA.1

Difficult transmembrane protein targets for therapeutic antibodies

Scientists develop breakthrough approach to create artificial allosteric sites in protein complexes

Unlocking the immune puzzle: study evaluates the immune impact of second booster COVID-19 vaccine

New radionuclide-based agent offers hope for treating a variety of cancers

Pangolin study uncovers novel strains of coronaviruses and raises concerns about origin

A new weapon against COVID: RBD-62 protein shows promising results in preventing severe disease

New model can quickly screen large libraries of potential drug compounds

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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