immunity News and Research

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Quantitative framework to investigate the dynamic mechanism of host immune response confronting SARS-CoV-2 infection

The authors highlight that they have created a quantitative framework that allows the dynamic mechanism of the immune response to SARS-CoV-2 to be properly investigated.

2 Feb 2022

Assessing an intranasal lentiviral booster against COVID-19 variants

A new study explores the possibility of vaccination via nasal route utilizing a lentiviral vaccination vector (LV) to be administered as a booster dose against COVID-19.

2 Feb 2022

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Researchers from China summarized the representative structures of SARS-CoV-2 proteins and discussed the development of novel therapeutic agents for targeting these proteins to treat and prevent COVID-19.

2 Feb 2022

Research supports the need for a 3rd mRNA COVID vaccine in patients taking immunosuppressants

New research posted to the medRxiv* preprint server finds patients with immune-mediated inflammatory diseases undergoing anti-TNF therapy had the greatest reduction of antibody levels three months after vaccination. In addition, they had weaker neutralization responses towards severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern.

1 Feb 2022

Scientists develop platform to track SARS-CoV-2 lineages

A team of researchers led by Laura D. Hughes from The Scripps Research Institute in California created an online platform called Outbreak.info to track over 40 million lineages and SARS-CoV-2 mutation across 7,000 locations.

1 Feb 2022

COVID-19 vaccines induce robust cellular immune response against SARS-CoV-2 Omicron

A team of scientists from the United States has recently demonstrated that current coronavirus disease 2019 (COVID-19) vaccines induce robust spike-specific T cell responses against the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

1 Feb 2022

Developing post-vaccination SARS-CoV-2 standard reference sera

A new study reports the generation of reference sera reagents that were obtained from subjects vaccinated with one of four COVID-19 vaccines.

1 Feb 2022

High levels of neutralizing antibodies against Omicron after BNT162b2 booster vaccination

Researchers analyze the neutralizing antibody levels against SARS-CoV-2 VOCs in individuals after receiving their second and third doses.

1 Feb 2022

Zika virus vaccine candidate found to be safe and effective in preclinical animal studies

A Zika virus vaccine candidate is effective at preventing the Zika virus passing from mother to fetus in preclinical animal studies, according to a new study in the journal npj Vaccines.

1 Feb 2022

Exploring beta-coronavirus neutralization by vaccine-induced murine antibody WS6

In a new study, researchers evaluated the neutralizing antibody titers in mice vaccinated with messenger ribonucleic acid (mRNA) encoding SARS-CoV-2 spike (S) protein.

1 Feb 2022

Study assesses anti-SARS-CoV-2 antibody response to mRNA-1273 vaccination over time

A new study has assessed the antibody responses to the mRNA-1273 Moderna vaccine over time.

31 Jan 2022

BA.2 sublineage of Omicron shows increased immune evasion and transmission

Recently, researchers from the University of Copenhagen have been investigating the spread of two sublineages of the Omicron variant among Danish households.

31 Jan 2022

Combined strategy suppresses the growth of deadly brain tumor

Short bursts of radiation therapy dramatically enhanced the efficiency of targeting glioblastomas with natural nanoparticle-based immunotherapy, thus suppressing growth of the deadly tumor, inducing anti-tumor immunity and prolonging survival in animal models, a research team at Massachusetts General Hospital has discovered.

31 Jan 2022

Yellow fever vaccine-vectored YF-S0 as a potent COVID-19 vaccine candidate

In a new study, a team of researchers developed YF-S0, an exceptionally potent COVID-19 vaccine candidate using live-attenuated yellow fever vaccine YF17D as a vector.

31 Jan 2022

Three exposures to SARS-CoV-2 spike protein can induce robust neutralizing antibodies against variants

In a new study, scientists revealed that three consecutive exposures SARS-CoV-2 spike protein through infection, vaccination, or both can induce strong neutralizing antibodies against a wide variety of viral variants, including omicron.

31 Jan 2022

How many lives would vaccine sharing have saved?

In a new study, researchers have been investigating different COVID-19 vaccine sharing simulations, and how they would affect affect global mortality.

31 Jan 2022

Estimating the impending endemic seasonality of SARS-CoV-2 in global population centers

A new study uses long-term data on the incidence of circulating coronaviruses and estimates the endemic seasonality of SARS-CoV-2 in global population centers.

31 Jan 2022

Vaccine hypersensitivity in children

A new paper published in Pediatric Allergy and Immunity provides a useful overview of such reactions in relation to pediatric vaccines.

31 Jan 2022

Vaccine-induced immunological memory is similar for Omicron and Delta SARS-CoV-2 variants

A new study by Norwegian researchers suggests that vaccine-induced immunological memory and the activation of recall responses in the body yields similar coverage for Omicron and Delta variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The paper is currently available on the medRxiv* preprint server while it undergoes peer review.

31 Jan 2022

Study shows homologous COVID boosters better than heterologous in most kidney transplant recipients

Researchers screen kidney transplant recipients to evaluate their serological responses following immunization with three doses of the COVID-19 vaccine.

30 Jan 2022

immunity News and Research

Quantitative framework to investigate the dynamic mechanism of host immune response confronting SARS-CoV-2 infection

Assessing an intranasal lentiviral booster against COVID-19 variants

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Research supports the need for a 3rd mRNA COVID vaccine in patients taking immunosuppressants

Scientists develop platform to track SARS-CoV-2 lineages

COVID-19 vaccines induce robust cellular immune response against SARS-CoV-2 Omicron

Developing post-vaccination SARS-CoV-2 standard reference sera

High levels of neutralizing antibodies against Omicron after BNT162b2 booster vaccination

Zika virus vaccine candidate found to be safe and effective in preclinical animal studies

Exploring beta-coronavirus neutralization by vaccine-induced murine antibody WS6

Study assesses anti-SARS-CoV-2 antibody response to mRNA-1273 vaccination over time

BA.2 sublineage of Omicron shows increased immune evasion and transmission

Combined strategy suppresses the growth of deadly brain tumor

Yellow fever vaccine-vectored YF-S0 as a potent COVID-19 vaccine candidate

Three exposures to SARS-CoV-2 spike protein can induce robust neutralizing antibodies against variants

How many lives would vaccine sharing have saved?

Estimating the impending endemic seasonality of SARS-CoV-2 in global population centers

Vaccine hypersensitivity in children

Vaccine-induced immunological memory is similar for Omicron and Delta SARS-CoV-2 variants

Study shows homologous COVID boosters better than heterologous in most kidney transplant recipients

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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