immunity News and Research

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Study highlights the patient heterogeneity in atopic dermatitis and demonstrates the promises of personalized treatment

Researchers investigated endotype-phenotype associations in atopic dermatitis (AD) beyond its general clinical severity.

4 Oct 2023

New model can calculate the probability of COVID-19 cluster occurrence

A research group has created a new model to calculate the probability of the occurrence of localized clusters caused by novel coronavirus infections.

3 Oct 2023

Could infants' robust immune responses reshape future vaccination strategies?

Utilizing next-gen sequencing techniques, researchers analyzed infants' immune responses to infections, uncovering a predominant innate immune activation unlike adults and older children. This insight could steer child vaccination research and pediatric infection management strategies, potentially revolutionizing infant healthcare.

3 Oct 2023

IU cancer researcher receives NCI grant to examine how immune cells support breast cancer development

A breast cancer researcher at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center received a five-year, $2.2 million grant from the National Cancer Institute to examine how certain immune cells support metastatic breast cancer development-;and how to stop it.

3 Oct 2023

New study reveals BA.2.86 subvariant's surprising dance with antibodies

Researchers examined the antigenicity of the emerging SARS-CoV-2 subvariant BA.2.86, finding that it is not resistant to neutralizing antibodies from previously infected or vaccinated individuals, although it does show increased binding affinity to the ACE-2 receptor. The study highlights the subvariant's sensitivity and resistance to different classes of monoclonal antibodies, offering insights for future treatment and vaccine development.

2 Oct 2023

Killer T cells in older adults found to be less effective at fighting influenza viruses

A world-first discovery has revealed special immune cells called ‘killer T cells’ in older adults, directed against influenza viruses, closely resemble those found in newborns and children, but struggle to recognise infected cells – a finding that unlocks the potential for the development of better vaccines and therapies tailored to different age groups.

30 Sep 2023

New research reveals how social isolation impacts behavior and lifespan in social species

Researchers used Camponotus fellah (carpenter ants) as a model species to perform behavioral tracking and ribonucleic acid-sequencing (RNA-seq) to study the transcriptome-level differences between socially isolated workers versus workers in groups.

29 Sep 2023

Vaxzevria vaccine boosts mucosal immunity in COVID-19 recovered

Study highlights the ability of the Vaxzevria vaccine in inducing robust mucosal antibody responses, especially in COVID-19-recovered individuals, showcasing a notable defense against various SARS-CoV-2 variants. However, it emphasizes the need for booster doses to enhance anti-SARS-CoV-2 mucosal immunity, especially in infection-naïve individuals, to broaden protection against emerging viral variants.

28 Sep 2023

Yeast in the gut linked to Crohn's disease inflammation, opening new doors for treatment

New study in Nature Medicine links yeast cells in the gastrointestinal tract to abnormal immune responses causing inflammation in Crohn's disease patients. The research suggests that these yeast-reactive T-cells could be a potential therapeutic target, offering new avenues for treatment.

27 Sep 2023

Researchers develop new way to boost immune cells' ability to fight TB

Tuberculosis is old-;ancient even. The infectious bacterial disease that plagued Old Testament Israelites and took down pharaohs was eventually stunted by vaccinations, antibiotics, and public health measures like isolation, but it hasn't been cured yet.

27 Sep 2023

Study details the key role played by neutrophils in ensuring survival of brain cancers

A Ludwig Cancer Research study has for the first time exhaustively analyzed immune cells known as neutrophils that reside in brain tumors, including gliomas, which develop in the brain itself, and cancers that spread there from the lung, breast and skin.

27 Sep 2023

Skin under pressure: tension affects skin's reaction to pollution

Researchers ratified previous findings that ozone (O3) exposure (an air pollutant) alters the antimicrobial peptide expression in the skin with and without tension.

27 Sep 2023

Could baseline gut microbiota predict the immune responses elicited by COVID-19 vaccines?

Researchers characterized the gut microbiota composition associated with the durability of COVID-19 vaccine-induced immunity.

27 Sep 2023

How do micronutrients influence neurological disorders?

The knowledge about micronutrients with regard to selected neurological diseases.

27 Sep 2023

Prolonged mismatch between calories eaten and burned may be putting many athletes at risk of REDs

The estimated prevalence of REDs varies by sport, ranging from 15% to 80%. The syndrome often goes unrecognised by athletes themselves, their coaches, and team clinicians, and may unwittingly be exacerbated by the 'sports culture,' because of the perceived short term gains on performance from intentionally or unintentionally limiting calorie intake, warns the Statement.

26 Sep 2023

UKHSA agrees a deal to produce life-saving vaccines in the UK

The UK Health Security Agency (UKHSA) has agreed a deal for millions of life-saving vaccines to be produced in the UK if a future influenza pandemic is ever declared.

26 Sep 2023

Monkeypox mimics smallpox vaccine's immune response, new study reveals

The study in Nature Communications reveals that MPOX infection triggers an anti-viral antibody response akin to that from smallpox vaccination. Utilizing a comprehensive array of ELISAs, scientists found a high level of specificity and sensitivity in detecting antibodies against both MPOX and smallpox, offering a new, accurate way to measure immune responses.

26 Sep 2023

Intranasal vaccine shows promise against COVID variants in hamsters

Intranasal mRNA-LNP vaccines show promise in Syrian golden hamsters, effectively reducing SARS-CoV-2 viral loads and lung pathology. The study suggests potential efficacy against new variants, setting the stage for future research in human applications.

25 Sep 2023

Research presents new approach to identify therapeutic targets for human diseases associated with protein phase separation

Recent research demonstrates that protein phase separation (PPS) is widely present in cells and drives a variety of important biological functions.

25 Sep 2023

Killer T cells in older adults resemble those found in newborns, but fall short in virus detection

A world-first discovery has revealed special immune cells called 'killer T cells' in older adults, directed against influenza viruses, closely resemble those found in newborns and children, but struggle to recognize infected cells – a finding that unlocks the potential for the development of better vaccines and therapies tailored to different age groups.

25 Sep 2023

immunity News and Research

Study highlights the patient heterogeneity in atopic dermatitis and demonstrates the promises of personalized treatment

New model can calculate the probability of COVID-19 cluster occurrence

Could infants' robust immune responses reshape future vaccination strategies?

IU cancer researcher receives NCI grant to examine how immune cells support breast cancer development

New study reveals BA.2.86 subvariant's surprising dance with antibodies

Killer T cells in older adults found to be less effective at fighting influenza viruses

New research reveals how social isolation impacts behavior and lifespan in social species

Vaxzevria vaccine boosts mucosal immunity in COVID-19 recovered

Yeast in the gut linked to Crohn's disease inflammation, opening new doors for treatment

Researchers develop new way to boost immune cells' ability to fight TB

Study details the key role played by neutrophils in ensuring survival of brain cancers

Skin under pressure: tension affects skin's reaction to pollution

Could baseline gut microbiota predict the immune responses elicited by COVID-19 vaccines?

How do micronutrients influence neurological disorders?

Prolonged mismatch between calories eaten and burned may be putting many athletes at risk of REDs

UKHSA agrees a deal to produce life-saving vaccines in the UK

Monkeypox mimics smallpox vaccine's immune response, new study reveals

Intranasal vaccine shows promise against COVID variants in hamsters

Research presents new approach to identify therapeutic targets for human diseases associated with protein phase separation

Killer T cells in older adults resemble those found in newborns, but fall short in virus detection

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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