immunity News and Research

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Climate change boosts infectious disease spread, hits the vulnerable hardest

Climate change is intensifying the spread of vector, water, and food-borne infections, disproportionately affecting vulnerable populations due to enhanced pathogen transmission in altered environmental conditions.

1 Apr 2024

Research suggests booster doses may be necessary for monkeypox immunity

New research to be presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April) shows that even in men who receives two doses of mpox vaccine intradermally, their level of antibodies to the virus falls to low or zero within the first few months if they have not received a previous smallpox vaccine.

1 Apr 2024

Study reveals waning antibody response to monkeypox vaccine over time

New research to be presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April) shows that the antibodies produced by Modified Vaccinia virus Ankara - Bavarian Nordic (MVA-BN) vaccination against mpox wane significantly within a year of receiving the vaccination – but in people with pre-existing immunity due to childhood smallpox vaccination in childhood, antibody levels remain high in almost all cases.

1 Apr 2024

Case study: Monkeypox breakthrough infection in fully vaccinated individual

New research to be presented at this year's European Congress of Clinical Microbiology and Infectious Diseases in Barcelona, Spain (27-30 April) details the case of a man who had received two doses of the monkey pox vaccine in Autumn, 2022 yet experienced a 'breakthrough' mpox infection in January 2024.

1 Apr 2024

Turning back the clock on aging immune systems: New treatment rejuvenates elderly defenses

Study demonstrated that selectively reducing myeloid-biased hematopoietic stem cells (my-HSCs) in aged mice rejuvenated the immune system, enhanced lymphopoiesis, reduced inflammation, and improved responses to viral infection, highlighting a potential strategy for countering age-related immune decline.

31 Mar 2024

Viral host jumps: Humans to animals transmission more common than previously thought

The evolutionary mechanisms underpinning recent viral host jumps.

27 Mar 2024

MMR vaccine slashes antibiotic use in toddlers: Nordic study shines light on broader benefits

Study demonstrates that administering the MMR vaccine to children under two, following three DTaP doses, significantly reduces the need for antibiotic treatments, highlighting potential non-specific protective effects.

26 Mar 2024

Single dengue vaccine dose shows mixed results: Protection hinges on prior exposure

Study investigates the protective effects of a single CYD-TDV vaccine dose against dengue virus in Filipino children, revealing that while the vaccine does not protect children with no or one prior dengue infection, it significantly reduces infection risk in those with two or more prior infections.

26 Mar 2024

GPT-4 shows expert-level accuracy in annotating cell types

GPT-4 can accurately interpret types of cells important for the analysis of single-cell RNA sequencing -- a sequencing process fundamental to interpreting cell types – with high consistency to that of time-consuming manual annotation by human experts of gene information, according to a study at Columbia University Mailman School of Public Health.

26 Mar 2024

Researchers identify viable vaccine targets for hepatitis C infections

By studying individuals who spontaneously clear hepatitis C infections, a team of researchers has identified viable vaccine targets for a disease that infects 70 million worldwide with case numbers increasing every year.

26 Mar 2024

Project PROTECTS launches to track acute respiratory infections across the United States

The City University of New York (CUNY) Institute for Implementation Science in Population Health (ISPH) and the CUNY Graduate School of Public Health and Health Policy (CUNY SPH), in collaboration with Pfizer, are initiating a critical two-year prospective epidemiologic study in the spring of 2024 to track acute respiratory infections across the United States.

22 Mar 2024

Investigational gene therapy shows promise for rare childhood neurodegenerative disease

An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy (GAN), was well tolerated and showed signs of therapeutic benefit in a clinical trial led by the National Institutes of Health.

20 Mar 2024

Astrocyte immune memory in multiple sclerosis pathology revealed

Immunological memory -; the ability to respond to a previously encountered antigen, or foreign substance, with greater speed and intensity on re-exposure is a hallmark of adaptive immunity.

20 Mar 2024

Immune cell protein identified as potential target for rare liver cancer treatment

Fibrolamellar carcinoma (FLC) is a rare liver cancer with a poor prognosis if not addressed early with surgery. The disease is caused by a single genetic mutation that creates a fusion protein.

20 Mar 2024

Ownership-based text messages boost COVID booster uptake

New research published in Nature Human Behavior suggests that text nudges encouraging people to get the COVID-19 vaccine, which had proven effective in prior real-world field tests, are also effective at prompting people to get a booster.

18 Mar 2024

Study reveals why COVID-19 antibodies fade quickly

Researchers at the Institute of Human Virology (IHV) at the University of Maryland School of Medicine published a new study in the Journal of Infectious Diseases investigating the antibody response following SARS-CoV-2 infection.

18 Mar 2024

Researchers study newborn piglets to better understand the progression of influenza

Although prevention and treatment strategies are available for influenza, they are not sufficient for vulnerable populations such as young children and newborns.

18 Mar 2024

Punitive prenatal drug laws lead to negative health outcomes

Contrary to some claims, laws that criminalize or otherwise punish drug use during pregnancy are more likely to worsen rather than improve health outcomes, according to a paper by researchers at Columbia University Mailman School of Public Health.

18 Mar 2024

Middle-aged adults in the U.S. experience higher levels of loneliness than European counterparts

Middle-aged adults in the U.S. tend to report significantly higher levels of loneliness than their European counterparts, possibly due in part to weaker family ties and greater income inequality, according to research published by the American Psychological Association.

18 Mar 2024

Rising antifungal resistance heightens concerns over invasive fungal infections

A global wave of infections caused by fungi growing drug-resistant has the medical community issuing precautions on how to protect yourself.

18 Mar 2024

immunity News and Research

Climate change boosts infectious disease spread, hits the vulnerable hardest

Research suggests booster doses may be necessary for monkeypox immunity

Study reveals waning antibody response to monkeypox vaccine over time

Case study: Monkeypox breakthrough infection in fully vaccinated individual

Turning back the clock on aging immune systems: New treatment rejuvenates elderly defenses

Viral host jumps: Humans to animals transmission more common than previously thought

MMR vaccine slashes antibiotic use in toddlers: Nordic study shines light on broader benefits

Single dengue vaccine dose shows mixed results: Protection hinges on prior exposure

GPT-4 shows expert-level accuracy in annotating cell types

Researchers identify viable vaccine targets for hepatitis C infections

Project PROTECTS launches to track acute respiratory infections across the United States

Investigational gene therapy shows promise for rare childhood neurodegenerative disease

Astrocyte immune memory in multiple sclerosis pathology revealed

Immune cell protein identified as potential target for rare liver cancer treatment

Ownership-based text messages boost COVID booster uptake

Study reveals why COVID-19 antibodies fade quickly

Researchers study newborn piglets to better understand the progression of influenza

Punitive prenatal drug laws lead to negative health outcomes

Middle-aged adults in the U.S. experience higher levels of loneliness than European counterparts

Rising antifungal resistance heightens concerns over invasive fungal infections

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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