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Rhodanine-based compounds show inhibitory activity to prevent aggregation of Tau proteins

The design of tailored peptide-polymer conjugates as drug-specific formulation additives offers access to next generation precision additives that can render problematic small organic drugs water-soluble and improve bioavailability.

30 Jun 2017

FDA authorizes marketing of test to aid in diagnoses of serious cancers

The U.S. Food and Drug Administration today allowed marketing of ClearLLab Reagents (T1, T2, B1, B2, M), the first agency authorized test for use with flow cytometry to aid in the detection of several leukemias and lymphomas, including chronic leukemia, acute leukemia, non-Hodgkin lymphoma, myeloma, myelodysplastic syndrome (MDS) and myeloproliferative neoplasms (MPN).

29 Jun 2017

New antiviral drug candidate effective against broad range of coronaviruses

A new antiviral drug candidate inhibits a broad range of coronaviruses, including the SARS and MERS coronaviruses, a multi-institutional team of investigators reports this week in Science Translational Medicine.

29 Jun 2017

Wyss Institute researchers develop new capture technology for cancer diagnostics

Cancerous tumors are formidable enemies, recruiting blood vessels to aid their voracious growth, damaging nearby tissues, and deploying numerous strategies to evade the body's defense systems.

28 Jun 2017

Research team receives NIH grant to develop new way to examine cancer cell metastasis

A University of Delaware researcher is part of a team that recently received a grant from the National Institutes of Health to develop a new way to examine how cancer cells metastasize.

28 Jun 2017

MSU researcher developing new miniature models to study heart disease and sickle cell anemia

A Mississippi State University researcher is developing new miniature models to better understand the factors that lead to heart disease and sickle cell anemia.

24 Jun 2017

Promoting innate detoxification mechanisms could be efficient strategy to reduce cellular oxidative stress

Promoting innate detoxification mechanisms in the body and discovering which supplements increase the efficacy of those biochemical pathways could be an efficient strategy to reduce the cellular oxidative stress and protect our health, according to an article published in the journal Food Chemistry, by the researchers Rafael Franco, from the Institute of Biomedicine of the University of Barcelona, and Eva Martínez Pinilla, from the Institute of Neurosciences of Asturias and the University of Oviedo.

21 Jun 2017

EKF POCT HbA1c testing confirmed as comparable to lab-based HPLC

EKF, announces recent study confirmed Quo-Test A1c point-of-care testing analyzer comparable to a lab-based HPLC system for the measurement of HbA1c.

From EKF Diagnostics 21 Jun 2017

Type I interferons could have role in natural improvement of RA during pregnancy

An international US-Danish team of scientists, led by Damini Jawaheer, Ph.D. at the UCSF Benioff Children's Hospital Oakland Research Institute, has identified a possible link between type I interferons and a natural improvement of rheumatoid arthritis (RA) during pregnancy.

21 Jun 2017

Cryopreservation of Embryos to Improve Assisted Reproductive Technology

If we were to compare the progression of cryopreservation technology during recent years, we would find that from 2004 to 2013 over a timeframe of a decade, there has been around a 2.5 times increase in the rate of frozen-thawed embryo transfers (FETs) that were reported to the Society for Assisted Reproductive Technology (SART). While the rate of fresh embryo transfers (ET) that were completed was the same.

From Sofia Hospital of Obstetrics, Gynecology and Reproductive Medicine 19 Jun 2017

Biomedical engineering professor wins $2 million grant for concussion research

Barclay Morrison, professor of biomedical engineering at Columbia Engineering, has won a $2 million five-year grant from the Paul G. Allen Family Foundation to study the underlying mechanisms of concussion.

15 Jun 2017

Researchers recapitulate pathological condition of retinal diseases on a chip

Approximately 80% of all sensory input is received via the eyes, so suffering from chronic retinal diseases that lead to blindness causes a significant decrease in the quality of life (QOL).

15 Jun 2017

Study suggests human embryos not susceptible to dying early as often claimed

How difficult is it to conceive? According to a widely-held view, fewer than one in three embryos make it to term, but a new study from a researcher at the University of Cambridge suggests that human embryos are not as susceptible to dying in the first weeks after fertilization as often claimed.

13 Jun 2017

Pyk2 deficits contribute to memory problems in Huntington’s disease mouse model

Researchers from the Institute of Neurosciences of the UB and from IDIBAPS together with a team from the University Pierre and Marie Curie and the Institute du Fer à Moulin, published a study in Nature Communications, which demonstrates that the regulation in Pyk2, a protein-tyrosine kinase, causes alterations of the synaptic plasticity involved in memory tasks, associated with the hippocampus in mouse models of neurodegenerative diseases, such as Huntington's.

13 Jun 2017

Magnetic nanoparticle aggregates can induce death of cancer cells

An international team in which a UPM researcher is involved has shown that it is possible to mechanically destroy cancer cells by rotating magnetic nanoparticles attached to them in elongated aggregates.

13 Jun 2017

Developing synthetic mediums for growing organoids

Organoids are bits of tissue grown in vitro, in a near-physiological 3D setting. The particularity consists in the fact that organoids retain features of the patient they are derived from, even when cultured outside of the human body. This is very different from what traditional, conventional cell culture has been able to do over the past 50 years or so.

13 Jun 2017

Study suggests promising therapeutic strategy for childhood brain tumor

A study published in Molecular Cancer Research reveals that a tumor suppressor gene p16 is turned off by a histone mutation (H3.3K27M), which is found in up to 70 percent of childhood brain tumors called diffuse intrinsic pontine glioma (DIPG).

6 Jun 2017

Researchers develop new approach to build better blood-brain barrier model

Delivering drugs to the brain is no easy task. The blood-brain barrier -a protective sheath of tissue that shields the brain from harmful chemicals and invaders - cannot be penetrated by most therapeutics that are injected into a person's blood stream.

6 Jun 2017

Research shows new Zika virus vaccine that offers 100% protection in mice

Research presented by Farshad Guirakhoo, Ph.D., Chief Scientific Officer, GeoVax, Inc., at the ASM Microbe 2017 meeting showed a new Zika virus vaccine that gives 100% protection in mice.

5 Jun 2017