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Adjunct therapy with human growth hormone in IVF shows no apparent benefit in women

Despite its occasional use as an adjunct in IVF, human growth hormone appears of little benefit to women having difficulty conceiving.

4 Jul 2016

Comprehensive NMR profiling module for detailed lipoprotein subclass analysis announced by Bruker (research use only)

At the 12th Annual Conference of the Metabolomics Society (www.metabolomics2016.org), Bruker announces a new, more comprehensive, more efficient and easy-to-use profiling module for detailed lipoprotein subclass analysis using Nuclear Magnetic Resonance (NMR).

From Bruker BioSpin - NMR, EPR and Imaging 1 Jul 2016

Novel therapeutic approach may be effective for disrupting bacterial biofilms

Biofilms are communities of bacteria that adhere to a surface and are nearly impossible to eradicate when they are pathogenic, or disease-causing.

30 Jun 2016

Researchers develop in vitro model system for investigating etiology of NAFLD

Researchers from the Institute for Stem Cell Research and Regenerative Medicine at the University Clinic of Düsseldorf have established an in vitro model system for investigating nonalcoholic fatty liver disease (NAFLD).

30 Jun 2016

LIF-treated muscle stem cells show promise in treatment of muscular dystrophy

Satellite cells are stem cells found in skeletal muscles. While transplantation of such muscle stem cells can be a potent therapy for degenerative muscle diseases such as Duchenne muscular dystrophy, these cells tend to lose their transplantation efficiency when cultured in vitro.

28 Jun 2016

ESCMID-ASM conference aims to speed up drug development processes for drug-resistant infections

The European Society of Clinical Microbiology and Infectious Diseases and the American Society for Microbiology (ASM) are jointly organizing a conference in Vienna from 21 – 23 September 2016 to help researchers accelerate the development of new antimicrobials for drug-resistant infections.

27 Jun 2016

KIT researchers develop 3D prostate model based on cryogels

A team of researchers led by Dr. Friederike J. Gruhl and Professor Andrew C. B. Cato at Karlsruhe Institute of Technology are developing a three-dimensional model for prostate cancer research based on cryogels.

25 Jun 2016

Novel combination therapy may help provide clinically successful treatment for AD

Resveratrol is a naturally occurring polyphenolic phytochemical produced in several plants, especially grapes skin and seeds. One epidemiological study reported a positive association between moderate red wine consumption and a low incidence of cardiovascular disease, known as the "French Paradox."

25 Jun 2016

Olive oil-based emulsion shows promise for mycobacterial treatment of bladder cancer

Researchers at the Universitat Autònoma de Barcelona with the collaboration of the Institute for Bioengineering of Catalonia, led by the professor of the UAB Department of Genetics and Microbiology Esther Julián, announced one year ago that the cells of the Mycobacterium brumae offer an improved alternative to current bladder cancer treatments such as BCG (an immunotherapy based on the Mycobacterium bovis), which can cause infections.

23 Jun 2016

Pretreatment smoking linked to poor prognosis in AI-treated patients

Among older aromatase inhibitor (AI)-treated patients with breast cancer, current smokers at treatment initiation have an increased risk of breast cancer events and distant metastases, say Swedish researchers.

23 Jun 2016

Researcher aims to develop easy-to-use, inexpensive sperm sorting devices to help infertile couples

The competition is fierce and only the strongest survive the obstacle course within the female reproductive tract. Of the millions of sperm that enter the vagina, only about 10 or so make it to the oocyte or egg, demonstrating how rigorous the natural sperm selection process really is.

17 Jun 2016

Scientists develop new software program that can help compare large amounts of metagenomes

Scientists from ITMO University, the Federal Research and Clinical Centre of Physical-Chemical Medicine and MIPT have developed a software program enabling them to quickly compare sets of DNA of microorganisms living in different environments. The researchers have already suggested exactly how the new program could be applied in practice.

16 Jun 2016

Study shows similarity between embryonic and reprogrammed stem cells

Stem cells are specialized undifferentiated cells that can divide and have the remarkable potential to develop into many different cell types in the body during early life and growth.

13 Jun 2016

Mathematical approach can help achieve optimal dosing for various drugs

In treating diseases with drugs, dosing is critical; too little is ineffective, while too much can be lethal. Colorado State University's Brad Reisfeld takes a mathematical approach to achieving optimal dosing for various drugs.

9 Jun 2016

Researchers identify lymphatic endothelial lineage that shows potential for new anti-cancer treatment

Identifying the cell of origin is crucial to understanding how a tumor develops and metastasizes and for developing targeted therapies.

8 Jun 2016

Yale researchers identify mechanisms responsible for human egg aging

Yale School of Medicine researchers have identified the molecular pathways involved in the aging of human eggs. This research could eventually lead to treatments to correct age-related damage and improve fertility in women age 40 and older.

8 Jun 2016

Boosting mitochondria transport may facilitate neuronal regeneration

Researchers at the National Institute of Neurological Disorders and Stroke have discovered that boosting the transport of mitochondria along neuronal axons enhances the ability of mouse nerve cells to repair themselves after injury.

8 Jun 2016

Researchers establish new method to culture kidney progenitor cells for regenerative medicine

Research into kidney regeneration, an organ that has been extremely difficult to regenerate, has taken a great stride forward with research coming out of a collaboration between Kumamoto University, Japan and the National Cancer Institute of the US.

7 Jun 2016

CNIO researchers avoid genetic manipulation to create lab mice with extra-long telomeres

The Telomeres and Telomerase Group at the Spanish National Cancer Research Centre, in collaboration with the Centre's Transgenic Mice Core Unit, has succeeded in creating mice in the laboratory with hyper-long telomeres and with reduced molecular ageing, avoiding the use of what to date has been the standard method: genetic manipulation.

3 Jun 2016

FDA approves blood-based cobas EGFR Mutation Test v2 for NSCLC patients

The U.S. Food and Drug Administration today approved the cobas EGFR Mutation Test v2, a blood-based companion diagnostic for the cancer drug Tarceva (erlotinib). This is the first FDA-approved, blood-based genetic test that can detect epidermal growth factor receptor (EGFR) gene mutations in non-small cell lung cancer patients.

2 Jun 2016

in vitro News and Research

Adjunct therapy with human growth hormone in IVF shows no apparent benefit in women

Comprehensive NMR profiling module for detailed lipoprotein subclass analysis announced by Bruker (research use only)

Novel therapeutic approach may be effective for disrupting bacterial biofilms

Researchers develop in vitro model system for investigating etiology of NAFLD

LIF-treated muscle stem cells show promise in treatment of muscular dystrophy

ESCMID-ASM conference aims to speed up drug development processes for drug-resistant infections

KIT researchers develop 3D prostate model based on cryogels

Novel combination therapy may help provide clinically successful treatment for AD

Olive oil-based emulsion shows promise for mycobacterial treatment of bladder cancer

Pretreatment smoking linked to poor prognosis in AI-treated patients

Researcher aims to develop easy-to-use, inexpensive sperm sorting devices to help infertile couples

Scientists develop new software program that can help compare large amounts of metagenomes

Study shows similarity between embryonic and reprogrammed stem cells

Mathematical approach can help achieve optimal dosing for various drugs

Researchers identify lymphatic endothelial lineage that shows potential for new anti-cancer treatment

Yale researchers identify mechanisms responsible for human egg aging

Boosting mitochondria transport may facilitate neuronal regeneration

Researchers establish new method to culture kidney progenitor cells for regenerative medicine

CNIO researchers avoid genetic manipulation to create lab mice with extra-long telomeres

FDA approves blood-based cobas EGFR Mutation Test v2 for NSCLC patients

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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