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Activation of MMP-9 enzyme leads to behavioral problems connected to chronic stress

Why is it that when people are too stressed they are often grouchy, grumpy, nasty, distracted or forgetful? Researchers from the Brain Mind Institute at EPFL have just highlighted a fundamental synaptic mechanism that explains the relationship between chronic stress and the loss of social skills and cognitive impairment. When triggered by stress, an enzyme attacks a synaptic regulatory molecule in the brain. This was revealed by a work published in Nature Communications.

19 Sep 2014

Rosuvastatin promotes bone growth in mice with achondroplasia symptoms

Skeletal dysplasia is a group of rare diseases that afflict skeletal growth through abnormalities in bone and cartilage. Its onset hits at the fetal stage and is caused by genetic mutations.

18 Sep 2014

Collaborative study takes important step toward finding targeted treatments for bladder cancer

The story of cancer care seems so simple: find the mutated gene that causes cancer and turn it off or fix it. But rarely does a single gene cause cancer. More often, many genes are altered together to drive the disease. So the challenge becomes sorting out which altered genes are the most to blame in which cancers.

16 Sep 2014

Hudson Robotics awarded NIH grant to develop HTS system for in vivo studies of zebrafish

Hudson Robotics, Inc., of Springfield, NJ, in cooperation with Johns Hopkins University, has recently been awarded an NIH grant to develop a commercially viable high-throughput screening (HTS) system for in vivo studies of zebrafish.

15 Sep 2014

New antiseptic agent holds promise for treatment of periodontitis

The study, published in the journal Science and Technology of Advanced Materials, by Shinichi Arakawa and colleagues at Tokyo Medical and Dental University and Japan's National Institute of Advanced Industrial Science and Technology, evaluated the bactericidal activities of ozone nano-bubble water - also known as NBW3 - against the two main bacterial agents that cause periodontitis as well as its toxicity to human oral tissue cells.

15 Sep 2014

New project aims at delivering innovative test to improve safety of chemical products, drugs

The Genotrace project, combining targeted research and technology transfer, aims at delivering an innovative test to improve the safety of chemical products, drugs, human and animal food and the environment.

10 Sep 2014

Growth factors present in human breast milk may protect against intestinal damage

Studies Suggest that ErbB4 Receptor Activation May Be a Novel Therapeutic Avenue for Intestinal Diseases Involving Epithelial Cell Death, According to Research Published in The American Journal of Pathology

10 Sep 2014

Abbott technology may help identify severe infections sooner, lower health care costs

A new study suggests a pioneering testing technology could reduce hospital stays by up to eight days and lower annual health care costs for people with serious infections by approximately $2.2 million (€1.5 million / £1.2 million).

9 Sep 2014

Center Director of Omni Eye Surgery describes promising option for managing lid disease

Omni Eye Services, a leading provider of ophthalmologic services at five locations in New York and New Jersey, today announced that Dr. Katherine M Mastrota, Center Director of Omni Eye Surgery in New York City, has written a treatment update for Contact Lenses Today describing a promising "new option for managing lid disease."

9 Sep 2014

Breast milk may protect premature infants from intestinal destruction

Premature infants are at increased risk for a potentially lethal gastrointestinal disease called necrotizing enterocolitis, or NEC.

9 Sep 2014

Nosopharm reports findings on Odilorhabdins that has potential to combat antibiotic resistance

Nosopharm, a specialist in the research and development of new anti-infective drugs, announces today its in vitro and in vivo findings for a novel antibacterial class, Odilorhabdins, which has the potential to combat antibiotic resistance.

4 Sep 2014

Exposure to certain phenols during pregnancy may disrupt growth of boys

A research consortium bringing together teams from Inserm, the Nancy and Poitiers University Hospitals, and the Centers for Disease Control and Prevention (CDC, Atlanta, USA), and coordinated by the Inserm and University of Grenoble Environmental Epidemiology team (Unit 823), has just published an epidemiological study indicating that exposure to certain phenols during pregnancy, especially parabens and triclosan, may disrupt growth of boys during foetal growth and the first years of life.

4 Sep 2014

Clinical studies to treat unmet medical need post-transplantation

A class of biotechnology drugs called monoclonal antibodies is now being tested in clinical studies to treat an unmet medical need post-transplantation, called delayed graft function

3 Sep 2014

BioLegend acquires shares of Covance Antibody Services

BioLegend, Inc. (BioLegend) acquired the shares of Covance Antibody Services Inc., a business unit of Covance, located in Dedham, Massachusetts, on August 29, 2014.

From BioLegend 2 Sep 2014

Cepheid releases Xpert Flu/RSV XC for accurate determination of Flu A, Flu B and RSV infection

Cepheid announced today the release of Xpert® Flu/RSV XC, an on-demand molecular test for rapid, accurate and reliable determination of Flu A, Flu B, and differentiation of RSV infection.

2 Sep 2014

Two fully automated molecular testing systems for blood and plasma donor screening launched by Roche

Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today the commercial availability of the cobas 6800/8800 Systems, two integrated and fully automated molecular testing systems for blood and plasma donor screening, in markets accepting the CE mark. The cobas 6800/8800 Systems offer the fastest time to results with the highest throughput available, along with the longest walk-away time, enabling laboratory staff to drive increased workflow efficiencies, while adapting to their ever-changing testing demands.

From Roche Sequencing and Life Science 2 Sep 2014

Researchers find way to take pediatric patient's skin cells

Researchers have found a way to take a pediatric patient's skin cells, reprogram the skin cells to function as heart valvular cells, and then use the cells as part of a tissue-engineered pulmonary valve. A proof of concept study in the September 2014 issue of The Annals of Thoracic Surgery provides more detail on this scientific development.

2 Sep 2014

Study for better understanding of neural circuitry and dynamic mechanisms controlling memory

A study just published in the prestigious Nature Neuroscience journal by, Sylvain Williams, PhD, and his team, of the Research Centre of the Douglas Mental Health University Institute and McGill University, opens the door towards better understanding of the neural circuitry and dynamic mechanisms controlling memory as well of the role of an essential element of the hippocampus - a sub-region named the subiculum.

1 Sep 2014

ESC launches first recommendations on use of all new oral anticoagulants in pulmonary embolism

The first recommendations on the use of all new oral anticoagulants in pulmonary embolism are published today in new ESC Guidelines.

30 Aug 2014

Study compares FK506 and rapamycin for Schwann cell migration, peripheral nerve regeneration

FK506 possesses a well-studied neuroregenerative effect, stimulating neurite extension in the presence of nerve growth factor in vitro, and enhancing nerve regeneration following nerve crush injury and isografting.

30 Aug 2014

in vitro News and Research

Activation of MMP-9 enzyme leads to behavioral problems connected to chronic stress

Rosuvastatin promotes bone growth in mice with achondroplasia symptoms

Collaborative study takes important step toward finding targeted treatments for bladder cancer

Hudson Robotics awarded NIH grant to develop HTS system for in vivo studies of zebrafish

New antiseptic agent holds promise for treatment of periodontitis

New project aims at delivering innovative test to improve safety of chemical products, drugs

Growth factors present in human breast milk may protect against intestinal damage

Abbott technology may help identify severe infections sooner, lower health care costs

Center Director of Omni Eye Surgery describes promising option for managing lid disease

Breast milk may protect premature infants from intestinal destruction

Nosopharm reports findings on Odilorhabdins that has potential to combat antibiotic resistance

Exposure to certain phenols during pregnancy may disrupt growth of boys

Clinical studies to treat unmet medical need post-transplantation

BioLegend acquires shares of Covance Antibody Services

Cepheid releases Xpert Flu/RSV XC for accurate determination of Flu A, Flu B and RSV infection

Two fully automated molecular testing systems for blood and plasma donor screening launched by Roche

Researchers find way to take pediatric patient's skin cells

Study for better understanding of neural circuitry and dynamic mechanisms controlling memory

ESC launches first recommendations on use of all new oral anticoagulants in pulmonary embolism

Study compares FK506 and rapamycin for Schwann cell migration, peripheral nerve regeneration

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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