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Researchers find NRF2 signaling plays a role in growth of tumor cells by altering metabolic pathways

Cancer cells have alteration in metabolic pathways as a result of oncogenes that promote tumor growth. NRF2 (nuclear factor erythroid-derived 2-related factor 2) works as a "master gene" that turns on stress response by increasing numerous antioxidants and pollutant-detoxifying genes to protect the lungs from variety of air pollutants such as diesel exhaust and cigarette smoke.

3 Jul 2013

BHR to demonstrate EKF Quo-Test HbA1c analyser at Heart UK's conference

EKF, announces today that the Quo-Test, its glycated haemoglobin analyser for near-patient monitoring of diabetes will be on show at Heart UK.

From EKF Diagnostics 2 Jul 2013

Key to treating neurodegenerative prion diseases may lie in ribosome, shows research

New research results from Uppsala University, Sweden, show that the key to treating neurodegenerative prion diseases such as mad cow disease and Creutzfeldt-Jakob disease may lie in the ribosome, the protein synthesis machinery of the cell. The results were recently published in the Journal of Biological Chemistry.

2 Jul 2013

Mixed results for acupuncture in improving IVF rates

Acupuncture, when used as a complementary or adjuvant therapy for in vitro fertilization (IVF), may be beneficial depending on the baseline pregnancy rates of a fertility clinic, according to research from the University of Maryland School of Medicine. The analysis from the University of Maryland Center for Integrative Medicine is published in the June 27 online edition of the journal Human Reproduction Update.

2 Jul 2013

UCSF researchers find that vitamin C may help stem cells, in vitro fertilization

Vitamin C affects whether genes are switched on or off inside mouse stem cells, and may thereby play a previously unknown and fundamental role in helping to guide normal development in mice, humans and other animals, a scientific team led by UC San Francisco researchers has discovered.

2 Jul 2013

Synthetic biology technology could lead to new antibiotics, modified protein-generators

Synthetic biology researchers at Northwestern University, working with partners at Harvard Medical School, have for the first time synthesized ribosomes -- cell structures responsible for generating all proteins and enzymes in our bodies -- from scratch in a test tube.

30 Jun 2013

Ingestion of nanoparticles at typical environmental levels unlikely to cause overt toxicity

Ingestion of commonly encountered nanoparticles at typical environmental levels is unlikely to cause overt toxicity, according to US researchers. Nevertheless there is insufficient evidence to determine whether chronic exposures could lead to subtle alterations in intestinal immune function, protein profiles, or microbial balance.

27 Jun 2013

Janssen, Johnson & Johnson Innovation establish IBD research alliance with Mount Sinai

Janssen Biotech, Inc. and Johnson & Johnson Innovation announced today the establishment of a research alliance with The Icahn School of Medicine at Mount Sinai to advance the scientific understanding of inflammatory bowel disease and the discovery of next generation therapeutic solutions.

27 Jun 2013

Study questions the beneficial effects of polyphenols on combating cardiovascular disease

Eating fruit or having a glass of red wine is seen as offering health benefits. The benefits are often pinned on polyphenols, natural chemicals—found in foods—referred to as flavonoids and phenolic acids, but also fragments of food proteins called peptides.

25 Jun 2013

Thirdhand smoke causes significant genetic damage in human cells

A study led by researchers from Lawrence Berkeley National Laboratory has found for the first time that thirdhand smoke-the noxious residue that clings to virtually all surfaces long after the secondhand smoke from a cigarette has cleared out-causes significant genetic damage in human cells.

21 Jun 2013

Combination therapy with myxoma virus and rapamycin can kill glioblastoma multiforme

A combination of the myxoma virus and the immune suppressant rapamycin can kill glioblastoma multiforme, the most common and deadliest malignant brain tumor, according to Moffitt Cancer Center research.

21 Jun 2013

Scientists use stem-cell technology to create research cell line from PDAC patient

Pancreatic cancer carries a dismal prognosis. According to the National Cancer Institute, the overall five-year relative survival for 2003-2009 was 6 percent.

21 Jun 2013

Scientists find way to attack dangerous bacteria that cause eye infections

Much as predators attack their prey in the animal world, there are bacteria that consume and kill other bacteria. Scientists are reporting new progress in putting the predator microbes to work - to attack dangerous bacteria that cause eye infections that lead to blindness and have grown resistant to antibiotics.

21 Jun 2013

Abbott RealTime HCV Genotype II assay receives FDA approval

The U.S. Food and Drug Administration today approved a test that identifies the genotype of hepatitis C virus that a patient is carrying. The Abbott RealTime HCV Genotype II, which can differentiate genotypes 1, 1a, 1b, 2, 3, 4, and 5,using a sample of an infected patient's blood plasma or serum, will aid health care professionals in determining the appropriate approach to treatment.

21 Jun 2013

Microfluidic devices can trap and sort bacteria and viruses in food and water

A new process for making a three-dimensional microstructure that can be used in the analysis of cells could prove useful in counterterrorism measures and in water and food safety concerns.

20 Jun 2013

NUS researchers develop highly realistic 3-D tumor model to track progress of drug therapy

A team of NUS researchers from the Departments of Bioengineering and Orthopaedic Surgery has developed a highly realistic three-dimensional (3-D) tumour model. As it replicates the conditions in the body, it is able to track the effectiveness and progress of drug therapy.

20 Jun 2013

New device that measures movement of immune cells may reduce risk of septic complications

Advances in emergency medicine and trauma surgery have had a significant impact on survival of patients in the days immediately after major injuries, including burns. Patients who survive the immediate aftermath of their injuries now are at greatest risk from infections - particularly the overwhelming, life-threatening immune reaction known as sepsis - or from inflammation-induced multiorgan failure.

20 Jun 2013

New breakthrough in chemical nanoengineering may help develop light-regulated therapeutic molecules

The scientific cooperation between chemists, biotechnologists and physicists from various Catalan institutes, headed by Pau Gorostiza, from the Institute for Bioengineering of Catalonia (IBEC), and Ernest Giralt, from the Institute for Research in Biomedicine (IRB Barcelona), has led to a breakthrough that will favor the development of light-regulated therapeutic molecules.

19 Jun 2013

Mendor's groundbreaking diabetes management platform receives CE mark

Finnish diabetes technology company Mendor announces today the CE mark for its groundbreaking diabetes management platform, Mendor Balance. This cloud-based platform seeks to introduce significant benefits to all the key stakeholders: patients, health care professionals, payers and the pharma industry.

18 Jun 2013

Special type of IVF may increase risk for insulin resistance among children

A special type of in vitro fertilization, or IVF, may increase the risk for insulin resistance among children conceived in this way, according to a new study from Greece. The results will be presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco.

18 Jun 2013

in vitro News and Research

Researchers find NRF2 signaling plays a role in growth of tumor cells by altering metabolic pathways

BHR to demonstrate EKF Quo-Test HbA1c analyser at Heart UK's conference

Key to treating neurodegenerative prion diseases may lie in ribosome, shows research

Mixed results for acupuncture in improving IVF rates

UCSF researchers find that vitamin C may help stem cells, in vitro fertilization

Synthetic biology technology could lead to new antibiotics, modified protein-generators

Ingestion of nanoparticles at typical environmental levels unlikely to cause overt toxicity

Janssen, Johnson & Johnson Innovation establish IBD research alliance with Mount Sinai

Study questions the beneficial effects of polyphenols on combating cardiovascular disease

Thirdhand smoke causes significant genetic damage in human cells

Combination therapy with myxoma virus and rapamycin can kill glioblastoma multiforme

Scientists use stem-cell technology to create research cell line from PDAC patient

Scientists find way to attack dangerous bacteria that cause eye infections

Abbott RealTime HCV Genotype II assay receives FDA approval

Microfluidic devices can trap and sort bacteria and viruses in food and water

NUS researchers develop highly realistic 3-D tumor model to track progress of drug therapy

New device that measures movement of immune cells may reduce risk of septic complications

New breakthrough in chemical nanoengineering may help develop light-regulated therapeutic molecules

Mendor's groundbreaking diabetes management platform receives CE mark

Special type of IVF may increase risk for insulin resistance among children

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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