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Gates Foundation awards USF $5.45M for malaria research

The University of South Florida received $5.45 million in grants from the Bill & Melinda Gates Foundation. The first grant is to create advanced devices that mimic the human liver to better study the life cycle of the malaria parasite - particularly the elusive liver stage where the disease may be most vulnerable to attack.

9 Feb 2011

Tufts announces public launch of Institute for Biomedical Partnerships, HUB website

Tufts University today announced the public launch of the Tufts Institute for Biomedical Partnerships website/HUB: www.tuftspharmapartners.org.

8 Feb 2011

PharmaMar initiates PM060184 Phase I clinical trial in patients with solid tumors

PharmaMar SA has announced the commencement of a Phase I clinical trial with PM060184 for patients with solid tumors. PM060184 is a marine-derived, synthetically-produced compound which has shown strong in vitro and in vivo antitumor activity and a favorable safety profile in preclinical toxicology studies. PM060184 is PharmaMar's sixth compound in clinical development.

7 Feb 2011

AMRI fourth quarter total revenue increases 12% to $48.6 million

AMRI today reported financial and operating results for the fourth quarter and full year ended December 31, 2010.

7 Feb 2011

Roche launches cobas TaqScreen DPX Test for parvovirus B19 and hepatitis A virus

Roche announced today that the cobas® TaqScreen DPX Test for use on the cobas s 201 system is now available in the US. It is the first commercial test to quantify parvovirus B19 and detect hepatitis A virus (HAV) simultaneously in one assay in human plasma.

5 Feb 2011

Cholesterol efflux capacity may protect against heart disease: Study

The discovery that high levels of high-density lipoprotein cholesterol are associated with reduced risk of cardiovascular disease has fostered intensive research to modify HDL levels for therapeutic gain. However, recent findings have called into question the notion that pharmacologic increases in HDL cholesterol levels are necessarily beneficial to patients.

4 Feb 2011

Concert and WRAIR enter CRADA to evaluate novel compound for seizure protection associated with TBI

Concert Pharmaceuticals, Inc. today announced that it has entered into a Cooperative Research and Development Agreement with the Walter Reed Army Institute of Research. The CRADA will allow the WRAIR to conduct preclinical testing on a novel compound derived from Concert's DCE Platform™ (deuterated chemical entity platform) for seizure protection associated with traumatic brain injury, a major public health concern.

3 Feb 2011

Uterine health is more relevant for fetus to achieve normal birth weight, full gestation

For women seeking pregnancy by assisted reproductive technologies, such as in-vitro fertilization, a new study shows that the health of the uterus is more relevant than egg quality for a newborn to achieve normal birth weight and full gestation.

2 Feb 2011

PET imaging may play a role in early evaluation of vandetanib response in thyroid cancer

Positron emission tomography can image metabolic changes following treatment with the protein kinase inhibitor vandetanib, helping to define the therapy response or the effectiveness of the therapeutic agent, according to research published in the February issue of The Journal of Nuclear Medicine.

1 Feb 2011

FDA, Optivia collaborate to examine effect of dietary supplements in drug-induced liver injury

Optivia Biotechnology, a leading provider of in vitro transporter assay services, today announced that the company and the U.S. Food and Drug Administration have signed a collaboration agreement to assess the effect of dietary supplements on key drug transporters.

1 Feb 2011

Octreotide inhibits HepG2 proliferation, study confirms

Hepatocellular carcinoma (HCC) is the fifth most common malignancy in the world and is estimated to cause approximately half a million deaths annually. Undoubtedly, the best available treatment for all liver tumors is complete surgical resection. However, the synthetic somatostatin analogue octreotide has been found effective in inhibiting tumor growth in a variety of experimental models. It has been reported that octreotide inhibits the proliferation and induces apoptosis of different HCC cell lines in vitro.

1 Feb 2011

LivDerma founder develops transdermal delivery system for effective pain relief

LivDerma's Dr. Joseph Gabriele has developed a unique, evidence-based transdermal delivery system to enter deep into the skin's dermis that produces strong pharmalogical effects.

29 Jan 2011

Maternal deaths related to IVF are a key indicator of risks to older women

Although still rare, maternal deaths related to in vitro fertilisation (IVF) are a key indicator of risks to older women, those with multiple pregnancy and those with underlying disease, warn experts in an editorial published on bmj.com today.

28 Jan 2011

Protein Erk necessary for nerve fibers to be wrapped with myelin

Researchers at the University of North Carolina at Chapel Hill have pinpointed a crucial function for a key player in the development of the nervous system. They found that this player - a protein called Erk - is necessary for nerve fibers to be wrapped with an insulating substance called myelin, which allows messages to be sent from the brain to the peripheral limbs and back again.

28 Jan 2011

Magnetic nanoparticles for ovarian cancer treatment

A paper published in the January issue of the journal Nanomedicine could provide the foundation for a new ovarian cancer treatment option - one that would use an outside-the-body filtration device to remove a large portion of the free-floating cancer cells that often create secondary tumors.

28 Jan 2011

Positive results from RXi's sd-rxRNA technology for development of novel therapeutics

RXi Pharmaceuticals Corporation, a recognized leader in RNAi-based therapeutics, announced today that, as part of its collaboration with miRagen Therapeutics, positive data were generated demonstrating that RXi's sd-rxRNA technology can be used, in vitro, to specifically enhance the activity of a microRNA of high interest to miRagen.

28 Jan 2011

QIAGEN announces formation of subsidiary in India

QIAGEN today announced the formation of its India subsidiary, QIAGEN India Pvt. Ltd., and the beginning of direct sales in the country. Until now, QIAGEN products have been sold in India through distributor partnerships.

From QIAGEN Manchester Limited 27 Jan 2011

Quest Diagnostics releases new data on oral fluid testing system

OraSure Technologies, the market leader in oral fluid diagnostics, announced today that Quest Diagnostics Incorporated released new data indicating that oral fluid revealed approximately five times more heroin use in the general U.S. workforce than previously believed.

From Quest Diagnostics 27 Jan 2011

ECCA and EDMA advance the EU health literacy debate

As part of the 2011 European Cervical Cancer Week, EDMA, the European Diagnostic Manufacturers Association and the ECCA, the European Cervical Cancer Association jointly organised the "Better Health Literacy for Better Health in Europe" dinner debate.

26 Jan 2011

NanoString Technologies launches nCounter Mouse miRNA Expression Assay Kit

NanoString Technologies, Inc., a privately held life sciences company marketing a complete solution for detecting and counting large sets of target molecules in biological samples, today announced the expansion of its microRNA (miRNA) product line with a multiplexed assay for profiling the mouse miRNA transcriptome.

From NanoString Technologies 25 Jan 2011

in vitro News and Research

Gates Foundation awards USF $5.45M for malaria research

Tufts announces public launch of Institute for Biomedical Partnerships, HUB website

PharmaMar initiates PM060184 Phase I clinical trial in patients with solid tumors

AMRI fourth quarter total revenue increases 12% to $48.6 million

Roche launches cobas TaqScreen DPX Test for parvovirus B19 and hepatitis A virus

Cholesterol efflux capacity may protect against heart disease: Study

Concert and WRAIR enter CRADA to evaluate novel compound for seizure protection associated with TBI

Uterine health is more relevant for fetus to achieve normal birth weight, full gestation

PET imaging may play a role in early evaluation of vandetanib response in thyroid cancer

FDA, Optivia collaborate to examine effect of dietary supplements in drug-induced liver injury

Octreotide inhibits HepG2 proliferation, study confirms

LivDerma founder develops transdermal delivery system for effective pain relief

Maternal deaths related to IVF are a key indicator of risks to older women

Protein Erk necessary for nerve fibers to be wrapped with myelin

Magnetic nanoparticles for ovarian cancer treatment

Positive results from RXi's sd-rxRNA technology for development of novel therapeutics

QIAGEN announces formation of subsidiary in India

Quest Diagnostics releases new data on oral fluid testing system

ECCA and EDMA advance the EU health literacy debate

NanoString Technologies launches nCounter Mouse miRNA Expression Assay Kit

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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