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Advaxis enters CRADA with NCI for development of live attenuated Listeria vaccines

Advaxis, Inc.,, the live, attenuated Listeria monocytogenes (Listeria) immunotherapy company, is pleased to announce it has signed a formal research agreement with the National Cancer Institute at the National Institutes of Health.

30 Oct 2010

Study suggests curcumin may be an effective therapy for liver fibrosis

Curcumin, a chemical that gives curry its zing, holds promise in preventing or treating liver damage from an advanced form of a condition known as fatty liver disease, new Saint Louis University research suggests.

30 Oct 2010

Novel small molecule inhibitors may provide new therapy for colon cancer

Researchers are one step closer to providing a new therapy for colon cancer, after findings revealed that a small molecule focal adhesion kinase (FAK) inhibitor known as Y15 effectively blocked cell viability, promoted detachment and apoptosis, and decreased tumor growth in mice. These findings were presented at the American Association for Cancer Research special conference on Colorectal Cancer: Biology to Therapy, held Oct. 27-30, 2010.

29 Oct 2010

Geron 2010 third quarter revenue increases from $494,000 to $546,000

Geron Corporation today reported financial results for the three and nine months ended September 30, 2010.

29 Oct 2010

Pharmasset's PSI-938 phase I monotherapy trial shows positive result for HCV treatment

Pharmasset, Inc. reported positive preliminary results today from its phase I monotherapy trial of PSI-352938 for the treatment of chronic hepatitis C (HCV). PSI-938 is a guanosine nucleotide analog polymerase inhibitor in development for the treatment of chronic HCV infection.

28 Oct 2010

Disinfection cap dispensing 70% isopropyl alcohol effectively disinfects IV needleless connectors

A study and review performed by clinicians of PICC Excellence, Inc. found a disinfection cap that dispenses 70% isopropyl alcohol is effective in disinfecting IV needleless connectors after five minutes. The study shows that if a needleless connector is covered and bathed in alcohol by the disinfection cap, no drying time is required to kill nearly all pathogens on the connector.

28 Oct 2010

AnaptysBio announces issuance of two new patents for SHM-XEL platform

AnaptysBio, Inc., a privately-held therapeutic antibody platform and product company, announced the issuance of patents in the US and Europe that provide additional coverage for its SHM-XEL platform. These patents extend AnaptysBio's leadership in the use of somatic hypermutation (SHM) for the discovery and optimization of antibodies and other proteins.

28 Oct 2010

Epigenomics presents data on Septin9 biomarker clinical study for colorectal cancer at UEGW

Epigenomics AG, the cancer diagnostics company, announced that new data obtained in a clinical study with the Company's proprietary Septin9 biomarker for the blood-based detection of colorectal cancer, were presented yesterday at the 18th United European Gastroenterology Week (UEGW) in Barcelona, Spain.

28 Oct 2010

Study finds green tea does not protect breast cancer

Green tea does not protect against breast cancer. A study of data from approximately 54,000 women, published in BioMed Central's open access journal Breast Cancer Research, found no association between drinking green tea and breast cancer risk.

28 Oct 2010

Prolonged use of glucosamine linked to greater risk of developing diabetes

High doses or prolonged use of glucosamine causes the death of pancreatic cells and could increase the risk of developing diabetes, according to a team of researchers at Universit- Laval's Faculty of Pharmacy. Details of this discovery were recently published on the website of the Journal of Endocrinology.

28 Oct 2010

GTC 2010 third fiscal quarter net loss decreases to $4.5 million from $26.2 million

GTC Biotherapeutics, Inc. today reported its financial results for the third fiscal quarter ended September 30, 2010.

28 Oct 2010

ENDOMETRIN Vaginal Insert offers effective luteal support in IVF procedures

Ferring Pharmaceuticals Inc. presented study results demonstrating that ENDOMETRIN (progesterone) Vaginal Insert provides effective luteal support compared to intramuscular (IM) progesterone-in-oil (PIO) in patients undergoing in vitro fertilization (IVF) using gonadotropin releasing hormone (GnRH) antagonist.

27 Oct 2010

MDI and Westburg enter exclusive distribution agreement for Detect-Ready MRSA panel in Benelux region

Molecular Detection Inc. (MDI), a company developing Detect-Ready™ tests designed to increase the speed and accuracy of infectious disease diagnosis, and life sciences and diagnostics distributor Westburg BV today announced that they have entered into an exclusive agreement for distribution of MDI's Detect-Ready MRSA panel in the Benelux region.

26 Oct 2010

First step in development of artificial human testicle

After more than 30 years of unsuccessful efforts by numerous investigators, researchers have now found a way to propagate primary human Sertoli cells in the laboratory. Derived from the testis, it has been difficult to maintain Sertoli cells, the "nurse" cells responsible for overseeing sperm production, outside of the human body.

26 Oct 2010

Examining genetic material of egg cells may inform about embryos health

Fertility procedures such as in vitro fertilization (IVF) require a couple and the doctor to place the risky bet that the multiple eggs they choose to fertilize will produce an embryo that will thrive in the uterus. Researchers cannot biopsy eggs directly because that would destroy them, but a new discovery by professors at Brown University and Women & Infants Hospital could lead to new insights about how eggs develop and ultimately inform judgments about how the embryos they produce will fare. The idea is to examine the genetic material the egg cells discarded when they were first forming, to see which genes they were expressing.

26 Oct 2010

Researchers create new high-content assay to increase human embryonic stem cell survival

A new technique for increasing the survival rates of human embryonic stem cells will revolutionize their use in drug discovery and therapy. Human embryonic stem cells often die during the process of isolation using enzymatic disaggregation or low-density plating, which limits their usefulness in drug discovery and basic research. Similarly, the low rate of attachment of implanted cells hinders cell therapy.

25 Oct 2010

GSN initiates trial of microarray PGD on pregnancy and implantation rates in IVF

Gene Security Network (GSN) announced today that it has initiated enrollment for a prospective randomized trial in collaboration with Ferring Pharmaceuticals to evaluate the impact of GSN's advanced preimplantation genetic diagnosis (PGD) with Parental Support™ on pregnancy and implantation rates in IVF.

25 Oct 2010

Cryo-Cell to launch new reproductive tissue service for cryopreserved embryos, oocyctes

Cryo-Cell International, Inc. one of the world's largest and most established family cord blood banks and global stem cell innovators, today announced plans at the annual meeting of the American Society of Reproductive Medicine (ASRM) to launch Cryology RTS, a new reproductive tissue storage service for cryopreserved embryos, oocyctes and sperm.

25 Oct 2010

NovaBay delivers two poster presentations on Aganocide compounds at IDSA Annual Meeting

NovaBay Pharmaceuticals, Inc. a clinical stage biotechnology company developing first-in-class, anti-infective compounds for the treatment and prevention of antibiotic-resistant infections, delivered two poster presentations on its compounds at the 48th Annual Meeting of the Infectious Diseases Society of America (IDSA) in Vancouver, Canada.

25 Oct 2010

Stanford Hospital opens Nuclear Medicine and Molecular Imaging Clinic

The Nuclear Medicine and Molecular Imaging Clinic opening this month at Stanford Hospital will help advance a new generation of diagnostic techniques for earlier detection and improved management of cancer, heart disease and neurological disorders.

22 Oct 2010

in vitro News and Research

Advaxis enters CRADA with NCI for development of live attenuated Listeria vaccines

Study suggests curcumin may be an effective therapy for liver fibrosis

Novel small molecule inhibitors may provide new therapy for colon cancer

Geron 2010 third quarter revenue increases from $494,000 to $546,000

Pharmasset's PSI-938 phase I monotherapy trial shows positive result for HCV treatment

Disinfection cap dispensing 70% isopropyl alcohol effectively disinfects IV needleless connectors

AnaptysBio announces issuance of two new patents for SHM-XEL platform

Epigenomics presents data on Septin9 biomarker clinical study for colorectal cancer at UEGW

Study finds green tea does not protect breast cancer

Prolonged use of glucosamine linked to greater risk of developing diabetes

GTC 2010 third fiscal quarter net loss decreases to $4.5 million from $26.2 million

ENDOMETRIN Vaginal Insert offers effective luteal support in IVF procedures

MDI and Westburg enter exclusive distribution agreement for Detect-Ready MRSA panel in Benelux region

First step in development of artificial human testicle

Examining genetic material of egg cells may inform about embryos health

Researchers create new high-content assay to increase human embryonic stem cell survival

GSN initiates trial of microarray PGD on pregnancy and implantation rates in IVF

Cryo-Cell to launch new reproductive tissue service for cryopreserved embryos, oocyctes

NovaBay delivers two poster presentations on Aganocide compounds at IDSA Annual Meeting

Stanford Hospital opens Nuclear Medicine and Molecular Imaging Clinic

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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