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Researcher aims to make early detection of melanoma faster, cheaper without need for biopsy

Melanoma is a form of skin cancer that becomes dangerous when it spreads, but is treatable in its early stages. Doctors diagnose melanoma by cutting away a piece of a suspicious skin lesion -- a procedure known as a biopsy -- and testing it for malignant cells.

14 Jul 2016

Researchers reveal molecular mechanism of autophagy initiation

Researchers revealed that Atg13 links autophagy initiation factors to each other using a string-like conformation, thereby promoting the association of diverse elements of the autophagy initiation machinery, initiating autophagosome formation through the recruitment of Atg9 vesicles and phosphorylation of various Atg factors.

12 Jul 2016

Researchers discover new signaling events that trigger metastasis in ovarian cancer cells

Like pancreatic cancer, cancer of the ovaries is notorious for being discovered at a relatively late stage - after it has spread to other sites in the body. It is not called "the silent killer" for nothing.

11 Jul 2016

New research shows how cholesterol medicine has beneficial effect on immune defence system

The cholesterol medicine simvastatin, which is one of the most commonly used pharmaceuticals in the world, also has a beneficial effect on the immune defence system with regard to diseases such as type 1 diabetes, multiple sclerosis and rheumatoid arthritis.

7 Jul 2016

New microfluidic device allows scientists to use safe electric fields to treat cancer

Researchers at MIT's research center in Singapore have developed a new microfluidic device that tests the effects of electric fields on cancer cells.

7 Jul 2016

Researchers identify astroglia-mediated mechanism for causing FXS symptoms in mice

A study published today in the Journal of Neuroscience led by Yongjie Yang of Tufts University School of Medicine identifies an astroglial trigger mechanism as contributing to symptoms of fragile X syndrome in mice.

6 Jul 2016

AOSSM presents research awards, grants at annual meeting

In order to recognize and encourage cutting-edge research in key areas of orthopaedic sports medicine, the American Orthopaedic Society for Sports Medicine will present research awards and grants during its Annual Meeting, July 7-10 in Colorado Springs, CO.

5 Jul 2016

Researchers discover human factor that drives maturation of helper T cells

A powerful arm of the immune system is production of antibodies that circulate through the blood and neutralize invading pathogens. Although B cells actually manufacture antibody proteins, the process is aided by neighboring T cells, which shower B cells with cytokines to make them churn out high-quality antibody proteins--and remember how to do so.

4 Jul 2016

Studies shed more light on relation between bacteria, immune system and antibiotics

Antibiotics and the immune system are the two forces that cope with bacterial infections. Now, two studies from Isabel Gordo's laboratory, at Instituto Gulbenkian de Ciência, show for the first time that resistance to antibiotics and to the immune system is interconnected in bacteria.

4 Jul 2016

Novel therapeutic approach may be effective for disrupting bacterial biofilms

Biofilms are communities of bacteria that adhere to a surface and are nearly impossible to eradicate when they are pathogenic, or disease-causing.

30 Jun 2016

Compounds extracted from parsley and dill seeds may help fight cancer

A team of Russian scientists from Moscow Institute of Physics and Technology, the N. D. Zelinsky Institute of Organic Chemistry, the Institute of Developmental Biology, and the Institute of Cell Biophysics proposed an efficient approach to a novel agents with anticancer activity.

29 Jun 2016

New electric mesh device wraps around the heart to deliver electrical impulses

A research team led by investigators at Beth Israel Deaconess Medical Center and Seoul National University has developed a new electric mesh device that can be wrapped around the heart to deliver electrical impulses and thereby improve cardiac function in experimental models of heart failure, a major public health concern and leading cause of mortality and disability.

29 Jun 2016

Therapeutic stem cells exit bloodstream in different way than previously thought

Researchers at North Carolina State University have discovered that therapeutic stem cells exit the bloodstream in a different manner than was previously thought. This process, dubbed angiopellosis by the researchers, has implications for improving our understanding of not only intravenous stem cell therapies, but also metastatic cancers.

29 Jun 2016

New computer model shows how spleen filters misshapen red blood cells

Researchers, led by Carnegie Mellon University President Subra Suresh and MIT Principal Research Scientist Ming Dao, have created a new computer model that shows how tiny slits in the spleen prevent old, diseased or misshapen red blood cells from re-entering the bloodstream.

28 Jun 2016

Federal government continues to ban valid scientific research on medicinal use of Cannabis sativa

The use of medical marijuana for millions of patients suffering from a wide range of health conditions and the subsequent therapeutic benefits has long been documented.

25 Jun 2016

Novel combination therapy may help provide clinically successful treatment for AD

Resveratrol is a naturally occurring polyphenolic phytochemical produced in several plants, especially grapes skin and seeds. One epidemiological study reported a positive association between moderate red wine consumption and a low incidence of cardiovascular disease, known as the "French Paradox."

25 Jun 2016

New Bruker In-Vivo Xtreme II system accelerates preclinical infectious disease research at University of Lausanne

Bruker’s recently introduced preclinical in vivo imaging system – In-Vivo Xtreme II™– is accelerating the preclinical research into infectious diseases being undertaken at the Institute of Microbiology at the University of Lausanne, Switzerland. Infectious diseases are the second leading cause of death worldwide.

From Bruker BioSpin - NMR, EPR and Imaging 24 Jun 2016

Researchers identify new potential target for pancreatic cancer treatment

Using an innovative approach to identify a cancer's genetic vulnerabilities by more swiftly analyzing human tumors transplanted into mice, researchers have identified a new potential target for pancreatic cancer treatment, published online in Cell Reports.

24 Jun 2016

New light-based technology facilitates deeper look into human body

New light-based technologies that facilitate a look inside the human body using light -- and without cutting into the tissue -- promise to enable both compact, wearable devices for point-of-care diagnostics as well as powerful new systems that provide even more information and from even deeper under the skin.

23 Jun 2016

Lack of Alix protein leads to occurrence of hydrocephalus in the brain

A team led by researchers at St. Jude Children's Research Hospital report that mice lacking the protein Alix develop hydrocephalus or "water on the brain." Alix ensures that epithelial cells of the choroid plexus are oriented correctly with respect to one another to prevent compromise of the epithelial barrier.

23 Jun 2016

in vivo News and Research

Researcher aims to make early detection of melanoma faster, cheaper without need for biopsy

Researchers reveal molecular mechanism of autophagy initiation

Researchers discover new signaling events that trigger metastasis in ovarian cancer cells

New research shows how cholesterol medicine has beneficial effect on immune defence system

New microfluidic device allows scientists to use safe electric fields to treat cancer

Researchers identify astroglia-mediated mechanism for causing FXS symptoms in mice

AOSSM presents research awards, grants at annual meeting

Researchers discover human factor that drives maturation of helper T cells

Studies shed more light on relation between bacteria, immune system and antibiotics

Novel therapeutic approach may be effective for disrupting bacterial biofilms

Compounds extracted from parsley and dill seeds may help fight cancer

New electric mesh device wraps around the heart to deliver electrical impulses

Therapeutic stem cells exit bloodstream in different way than previously thought

New computer model shows how spleen filters misshapen red blood cells

Federal government continues to ban valid scientific research on medicinal use of Cannabis sativa

Novel combination therapy may help provide clinically successful treatment for AD

New Bruker In-Vivo Xtreme II system accelerates preclinical infectious disease research at University of Lausanne

Researchers identify new potential target for pancreatic cancer treatment

New light-based technology facilitates deeper look into human body

Lack of Alix protein leads to occurrence of hydrocephalus in the brain

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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