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Innovative research technique may help understand early stage kidney disease

UT Dallas scientists are developing an innovative research technique that could help urologists better understand the early stages of kidney disease.

19 May 2016

Pediatric feasibility study results set stage for clinical trial of world’s first bioabsorbable heart valve enabling Endogenous Tissue Restoration

One-year follow-up results from a pediatric feasibility study of Xeltis bioabsorbable cardiovascular pulmonary graft have been presented as late-breaker at the 96th American Association for Thoracic Surgery annual meeting today.

19 May 2016

New bio-mimicry method allows scientists to track cells in vivo using MRI during preclinical, clinical trials

Researchers led by Carnegie Mellon University Professor of Biological Sciences Chien Ho have developed a new method for preparing mesenchymal stem cells (MSCs) that not only leads to the production of more native stem cells, but also labels them with a FDA approved iron-oxide nanoparticle (Ferumoxytol).

18 May 2016

PENTAX Medical releases OPTIVISTA EPK-i7010 Video Processor for more accurate endoscopic in vivo diagnosis

PENTAX Medical launches a world first for endoscopy, the OPTIVISTA EPK-i7010 Video Processor, featuring both digital and optical enhancements, in the European, Middle Eastern & African (EMEA) markets.

From PENTAX Medical Company 17 May 2016

Gene therapy shows promise in treating glioblastoma

A team from the International School for Advanced Studies in Trieste has obtained very promising results by applying gene therapy to glioblastoma.

13 May 2016

LaVision BioTec to debut latest light sheet microscope at analytica 2016

LaVision BioTec, developers of advanced microscopy solutions for the life sciences, will demonstrate their latest light sheet microscope, the UltraMicroscope II at the forthcoming analytica 2016 meeting in Munich.

9 May 2016

Implication of microRNAs in cancer development greater than previously thought

Small, non-coding molecules called microRNAs are known to play an important role in cancer development. Researchers now have shown their significance is greater than previously thought, a finding that could lead to new therapeutic approaches for the most common and deadly form of ovarian cancer.

6 May 2016

Studies show mango consumption may contribute to protective health effects

Four new studies surrounding the effects of mango consumption suggest this superfruit has the potential to help combat adverse effects associated with high fat diets and obesity (animal study), as well inhibit growth of fat cells (anti-lipogenic properties in an in-vivo study), slow advancement of breast cancer tumors (animal study), as well as improve regularity and decrease inflammation associated with constipation (human subject study).

6 May 2016

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

University of Alabama at Birmingham researchers report the first documentation that suppressing a key cell-signaling pathway in a rat model of Parkinson's disease reduces pathogenesis. Oral administration of AZD1480 — one of the JAK/STAT pathway inhibitors generally known as Jakinibs — lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson's.

4 May 2016

New inexpensive technology can effectively sterilise medical implants

International researchers led by the University of Bath have demonstrated a cheap, effective and environmentally-friendly way to sterilise medical implants without changing their properties, in contrast to some techniques.

30 Apr 2016

Group of gamma-protocadherins linked with neurons help regulate growth of dendrites

When you think of a neuron, imagine a tree. A healthy brain cell indeed looks like a tree with a full canopy. There's a trunk, which is the cell's nucleus; there's a root system, embodied in a single axon; and there are the branches, called dendrites.

28 Apr 2016

Study reveals surprising results that may impair future therapeutic approaches in TGF-beta pathway

Researchers at Helmholtz Zentrum München describe how breast cancer cells challenged with a small-molecule inhibitor targeting specific invasive properties switch to an alternative mode-of-action, rendering them even more aggressive. The results may impair future therapeutic approaches in the TGF-beta pathway and are published in the journal 'Oncotarget'.

27 Apr 2016

Researchers reveal how bile component taurine attracts Vibrio cholera

A group of researchers from Osaka University, Hosei University, and Nagoya University have revealed the molecular mechanism that Vibrio cholerae, the etiological agent of cholera, is attracted by bile. This group has also successfully detected the ligand binding to the bacteria chemoreceptor in vivo for the first time. These results may significantly advance research on mechanism and control of V. cholerae.

26 Apr 2016

New study explores mechanisms that control size, shape of tubular organ systems

A new study from the group of Holger Gerhardt in collaboration with Katie Bentley's Lab addresses a long standing question in the wider field of developmental biology and tissue patterning in general, and in the vascular biology field in particular: 'What are the fundamental mechanisms controlling size and shape of tubular organ systems'.

21 Apr 2016

Scientists develop new strategy to combat wide range of viruses

Scientists and health officials are marshalling forces to fight Zika, the latest in a string of recent outbreaks. Many of these efforts target that virus specifically, but some researchers are looking for a broader approach. Now one team reports in ACS' journal Macromolecules a new strategy to fight a wide range of viruses that appears to be safe in vivo and could evade a virus's ability to develop resistance.

21 Apr 2016

Vegetable-based polyphenol enhances wound healing

A research group led by Osaka University found a plant-based polyphenol, promotes the migration of Mesenchymal Stem Cells (MSCs) in blood circulation and accumulates them in damaged tissues to improve wound healing. It is anticipated that the results will be used for stem cell treatments for cutaneous disorders associated with various damage and lesions.

21 Apr 2016

Researchers identify protein that helps cancer cells to spread

Aggressive cancer cells spread from a tumour to another part of the body through the blood vessel. To be able get in and out of the blood vessel, the cancer cell needs to penetrate tissue. Researchers from The University of Bergen have discovered a protein that the cancer cell uses like scissors to cut up tissue, so it can spread from a tumour to a new organ.

13 Apr 2016

Novel biochemical method can extend lifetime of implantable medical devices

Blood-contacting implantable medical devices, such as stents, heart valves, ventricular assist devices, and extracorporeal support systems, as well as vascular grafts and access catheters, are used worldwide to improve patients' lives. However, these devices are prone to failure due to the body's responses at the blood-material interface; clots can form and inflammatory reactions can prevent the device from performing as indicated. Currently, when this occurs, the only solution is to replace the device.

13 Apr 2016

New clinical data highlights potential of AB-PA01 to treat P. aeruginosa infections in CF patients

AmpliPhi Biosciences Corporation, a global leader in the development of bacteriophage-based antibacterial therapies to treat drug-resistant infections, presented data at the European Congress of Clinical Microbiology and Infectious Diseases summarizing both the in vitro and in vivo activity of its proprietary, investigational phage mix AB-PA01.

13 Apr 2016

Researchers investigate biochemical, physiological characteristics of facial and extraocular muscles

In a new study, a research team at Basel University Hospital in Switzerland investigates the biochemical and physiological characteristics of orbicularis oculi, a group of facial muscles that control the eyelids and are selectively spared or involved in different neuromuscular disorders. What they found also helps to explain why another set of muscles—the extraocular muscles that control the movement of the eye—are not affected by Duchenne muscular dystrophy, congenital muscular dystrophy, and aging.

12 Apr 2016

in vivo News and Research

Innovative research technique may help understand early stage kidney disease

Pediatric feasibility study results set stage for clinical trial of world’s first bioabsorbable heart valve enabling Endogenous Tissue Restoration

New bio-mimicry method allows scientists to track cells in vivo using MRI during preclinical, clinical trials

PENTAX Medical releases OPTIVISTA EPK-i7010 Video Processor for more accurate endoscopic in vivo diagnosis

Gene therapy shows promise in treating glioblastoma

LaVision BioTec to debut latest light sheet microscope at analytica 2016

Implication of microRNAs in cancer development greater than previously thought

Studies show mango consumption may contribute to protective health effects

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

New inexpensive technology can effectively sterilise medical implants

Group of gamma-protocadherins linked with neurons help regulate growth of dendrites

Study reveals surprising results that may impair future therapeutic approaches in TGF-beta pathway

Researchers reveal how bile component taurine attracts Vibrio cholera

New study explores mechanisms that control size, shape of tubular organ systems

Scientists develop new strategy to combat wide range of viruses

Vegetable-based polyphenol enhances wound healing

Researchers identify protein that helps cancer cells to spread

Novel biochemical method can extend lifetime of implantable medical devices

New clinical data highlights potential of AB-PA01 to treat P. aeruginosa infections in CF patients

Researchers investigate biochemical, physiological characteristics of facial and extraocular muscles

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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