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Electrical stimulation of hippocampus activates dormant memory cells

The electrical stimulation of the hippocampus in in-vivo experiments activates precisely the same receptor complexes as learning or memory recall. This has been discovered for the first time and the finding has now been published in the highly respected journal "Brain Structure Function".

24 Feb 2014

Addition of confocal laser endomicroscopy to HDWLE improves diagnosis of Barrett's esophagus

New research shows that the addition of confocal laser endomicroscopy to high-definition white-light endoscopy enables improved real-time endoscopic diagnosis of Barrett's esophagus dysplasia (neoplastic tissue) by using targeted biopsies of abnormal mucosa to reduce unnecessary mucosal biopsies and potentially reduce costs.

20 Feb 2014

Cystinosis Research Foundation granted $2.15M in 2013 to researchers investigating cure for cystinosis

The Cystinosis Research Foundation awarded $2,153,048 in 2013 to researchers investigating better treatments and a cure for cystinosis, a rare metabolic and genetic disease that afflicts about 500 children and young adults in the United States and 2,000 worldwide.

19 Feb 2014

iCAD total revenue for Q4 2013 increases 16.8% to $9.1 million

iCAD, Inc., an industry-leading provider of advanced image analysis, workflow solutions and radiation therapy for the early identification and treatment of cancer, today reported financial results for the three and twelve months ended December 31, 2013.

19 Feb 2014

Scientists propose improved method of screening salmonella vaccines in small animal studies

An innovative vaccine technology makes use of reengineered salmonella to deliver protective immunity. If such recombinant attenuated salmonella vaccines or RASVs can be perfected, they hold the promise of safe, lost-cost, orally administered defenses against viral, bacterial, fungal and parasitic infections.

19 Feb 2014

Researchers present new drug candidate that selectively kills cancer cells through starvation

In a study published in Nature Communications, researchers at Karolinska Institutet and Uppsala University in Sweden present a new drug candidate, which selectively kills dormant cells within a cancer tumour through starvation.

19 Feb 2014

Porvair Sciences to showcase specialist microplate products at Pittcon, Analytica and Genomics Research 2014

Porvair Sciences has announced that it will be showing its latest specialist microplates and microplate equipment at the forthcoming Pittcon 2014 (Chicago), Analytica 2014 (Munich) and Genomics Research 2014 (San Francisco) exhibitions.

From Chromatrap® - Porvair Sciences Ltd 11 Feb 2014

Prions and their shadow proteins: an interview with Dr Jiri Safar, Co-Director of the National Prion Disease Pathology Surveillance Center

The prion diseases were originally discovered by Dr Gajdusek and Dr Gibbs. The first disease discovered was Kuru, which was affecting native tribes in the Papua New Guinea highlands in the 1950s.

9 Feb 2014

Scientists engineered microchip coated with blood vessel cells to study cardiovascular nanomedicine

Designing nanomedicine to combat diseases is a hot area of scientific research, primarily for treating cancer, but very little is known in the context of atherosclerotic disease.

5 Feb 2014

Ronald G. Crystal wins Pioneer Award from Human Gene Therapy

In recognition of his seminal work on adenoviral vectors, which accelerated the translation of gene therapy from the research laboratory to the clinic, Ronald G. Crystal, MD (Weill Cornell Medical College, Cornell University, New York City), has received a Pioneer Award from Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

31 Jan 2014

Transgenic mouse model validates mutant IDH2 protein as candidate for targeted anticancer therapies

In recent years, mutations in two metabolic enzymes, isocitrate dehydrogenase-1 and 2 (IDH1 and IDH2), have been identified in approximately 20 percent of all acute myeloid leukemias (AML). As a result, mutant IDH proteins have been proposed as attractive drug targets for this common form of adult leukemia.

29 Jan 2014

Study shows melatonin hormone may inhibit tumor growth and cell production

An early stage study shows melatonin - a hormone that regulates the body's sleep and awake cycles - may have the potential to help slow the growth of certain breast cancer tumors, according to researchers from Henry Ford Hospital in Detroit and Foundation for Research Support of the State of S-o Paulo.

28 Jan 2014

Phasefocus reports on new ptychography paper published in Nature Scientific Reports

Cell imaging often relies on synthetic or genetic fluorescent labels, to provide contrast which can be far from ideal for imaging cells in their in vivo state. We report on the biological application of a label-free, high contrast microscopy technique known as ptychography, in which the image producing step is transferred from the microscope lens to a high-speed phase retrieval algorithm.

From Phase Focus Limited 28 Jan 2014

New data on extending the serum half-life of albumin in vivo announced by Novozymes Biopharma

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27 Jan 2014

First patient enrolled pilot clinical trial of NovoTTF Therapy plus gemcitabine for pancreatic adenocarcinoma

Novocure announced today that the first patient has enrolled in the EF-20 Study, an open label, pilot clinical trial of NovoTTF Therapy plus gemcitabine as first-line therapy for patients with locally advanced and metastatic pancreatic adenocarcinoma.

25 Jan 2014

New techniques simplify current test procedures for developing new medications

When developing new medications, biologists and pharma- cologists test different active ingredients and chemical compounds. The main purpose is to find out how biological cells react to these substances.

24 Jan 2014

Adding quinoa to gluten-free diet of patients with celiac disease is well-tolerated

Adding quinoa to the gluten-free diet of patients with celiac disease is well-tolerated, and does not exacerbate the condition, according to new research published in The American Journal of Gastroenterology. Dr. Victor F. Zevallos, from the Department of Gastroenterology, King's College London, United Kingdom, evaluated the in-vivo effects of consuming quinoa in adult celiac patients. Quinoa, a highly nutritious grain, is traditionally recommended as part of a gluten-free diet.

22 Jan 2014

Damon Runyon Cancer Research Foundation awards $2.25M to six innovative young scientists

The Damon Runyon Cancer Research Foundation announced that six scientists with novel approaches to fighting cancer have been named 2014 recipients of the Damon Runyon-Rachleff Innovation Award. The grant of $450,000 over three years is awarded each year to early career scientists whose projects have the potential to significantly impact the prevention, diagnosis and treatment of cancer.

21 Jan 2014

Vivaldi Biosciences inks agreement with NIAID to evaluate LAIV candidates against influenza A

Vivaldi Biosciences Inc., a clinical-stage biotechnology company developing live attenuated influenza vaccines against seasonal and pandemic influenza, today announced that it has signed a Cooperative Research and Development Agreement with the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to generate and evaluate in preclinical studies LAIV candidates against influenza A(H7N9).

21 Jan 2014

RBCC's partner Nano3D Biosciences develops new 3D bioprinting system

Rainbow Coral Corp. is well-positioned to capitalize on the revolution in medicine being spurred on by 3D printing technology thanks to the innovative BiO Assay, a new 3D bioprinting system developed by RBCC's joint venture partner, Nano3D Biosciences (n3D).

20 Jan 2014

in vivo News and Research

Electrical stimulation of hippocampus activates dormant memory cells

Addition of confocal laser endomicroscopy to HDWLE improves diagnosis of Barrett's esophagus

Cystinosis Research Foundation granted $2.15M in 2013 to researchers investigating cure for cystinosis

iCAD total revenue for Q4 2013 increases 16.8% to $9.1 million

Scientists propose improved method of screening salmonella vaccines in small animal studies

Researchers present new drug candidate that selectively kills cancer cells through starvation

Porvair Sciences to showcase specialist microplate products at Pittcon, Analytica and Genomics Research 2014

Prions and their shadow proteins: an interview with Dr Jiri Safar, Co-Director of the National Prion Disease Pathology Surveillance Center

Scientists engineered microchip coated with blood vessel cells to study cardiovascular nanomedicine

Ronald G. Crystal wins Pioneer Award from Human Gene Therapy

Transgenic mouse model validates mutant IDH2 protein as candidate for targeted anticancer therapies

Study shows melatonin hormone may inhibit tumor growth and cell production

Phasefocus reports on new ptychography paper published in Nature Scientific Reports

New data on extending the serum half-life of albumin in vivo announced by Novozymes Biopharma

First patient enrolled pilot clinical trial of NovoTTF Therapy plus gemcitabine for pancreatic adenocarcinoma

New techniques simplify current test procedures for developing new medications

Adding quinoa to gluten-free diet of patients with celiac disease is well-tolerated

Damon Runyon Cancer Research Foundation awards $2.25M to six innovative young scientists

Vivaldi Biosciences inks agreement with NIAID to evaluate LAIV candidates against influenza A

RBCC's partner Nano3D Biosciences develops new 3D bioprinting system

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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