in vivo News and Research

RSS

Prairie Technologies acquired by Bruker

Bruker Corporation today announced that it has acquired Prairie Technologies, Inc. (Prairie), a provider of life science fluorescence microscopy products. The acquisition strengthens Bruker’s position in life science markets, adding to the Bruker Nano Surfaces Division’s existing life science atomic force microscopy (Bio-AFM) systems.

From Bruker Nano Surfaces and Metrology 13 Sep 2013

CardioExcyte 96 for cardiac toxicity profiling and screening introduced by Nanion

Cardiac safety assessment is a vital part of drug development since late withdrawals of compound candidates, due to heart liability issues such as ventricular arrhythmia, are very costly. In-vivo methods give highly relevant information but are extremely low throughput allowing the analysis of only a handful of compounds.

From Nanion Technologies 13 Sep 2013

High resolution of U‐SPECT/CT system helps perform kinetic analyses of viral spread in vivo

The ability to visualize and analyze the spread of viral infections in primary and metastatic tumors is an essential component in characterizing the therapeutic efficacy of oncolytic viruses.

12 Sep 2013

Wake Forest Baptist conducts $24 million project to accelerate development of new therapies

Whether it's the Ebola virus or Sarin and Ricin, a key to responding to chemical or biological attacks is having effective antidotes at the ready. To accelerate the development of new therapies, Wake Forest Baptist Medical Center's Institute for Regenerative Medicine is leading a unique $24 million federally funded project to develop a "body on a chip" that will be used to develop these countermeasures.

12 Sep 2013

arGEN-X generates potent antibody antagonists of Nav1.7 using SIMPLE Antibody technology

arGEN-X, a clinical stage human monoclonal antibody therapeutics company, announces it has successfully generated potent antibody antagonists of Nav1.7, using its proprietary SIMPLE Antibody™ technology.

12 Sep 2013

Exposing young girls to ionizing radiation can raise risk of breast cancer later in life

Exposing young women and girls under the age of 20 to ionizing radiation can substantially raise the risk of their developing breast cancer later in life. Scientists may now know why. A collaborative study, in which Berkeley Lab researchers played a pivotal role, points to increased stem cell self-renewal and subsequent mammary stem cell enrichment as the culprits.

12 Sep 2013

North Carolina professor receives 2013 New Scholar in Aging Award from Ellison Medical Foundation

Li Qian, PhD, an assistant professor in the University of North Carolina School of Medicine, has received a 2013 New Scholar in Aging Award from the Ellison Medical Foundation.

12 Sep 2013

Umbilical cord mesenchymal stem cells may have targeting capacity for glioma

Glioblastoma is the most common ma-lignant primary brain tumor in adults. The aggressive growth manner, characterized by marked angiogenesis and extensive tumor cell invasion into normal brain parenchyma with frequent formation of tumor microsatellites at distal sites, makes eradication impossible even after extensive microsurgical resection combined with current standard chemoradiation and adjuvant temozolomide.

11 Sep 2013

Scientists use nanodiamonds to boost delivery of drug to leukemic cells

By binding multiple molecules of a common leukemia drug with nanodiamonds, scientists from the National University of Singapore (NUS) and University of California, Los Angeles (UCLA) managed to boost the delivery of the drug to leukemic cells and retain the drug within the cells to combat the cancer.

11 Sep 2013

Chemists Find New Way To Put The Brakes On Cancer

...

10 Sep 2013

Researchers find key mechanism behind Alzheimer's disease

Alzheimer's disease affects more than 26 million people worldwide. It is predicted to skyrocket as boomers age-nearly 106 million people are projected to have the disease by 2050.

7 Sep 2013

Non-adherent bone marrow cell-derived mesenchymal stem cells could differentiate into neuronal-like cells

It is widely believed that bone marrow mesenchymal stem cells are highly adherent fibroblastic cells, defined as colony-forming unit-fibroblasts. Nevertheless, a few reports have shown that the non-adherent bone marrow cells can give rise to colony-forming unit-fibroblasts in vitro, and possess a certain differentiation potential.

6 Sep 2013

FIBRO-TARGETS project aims to identify mechanisms involved in MIF, define therapeutic approaches

Unravelling the mechanisms of cardiac fibrosis will lead to the discovery of therapeutic target candidates for various cardiac diseases. FIBRO-TARGETS brings together eleven European expert teams from six different countries both from public research institutes and European biotechs.

5 Sep 2013

New laser-based tool could improve accuracy of brain tumor surgery

In the battle against brain cancer, doctors now have a new weapon -- a new imaging technology that will make brain surgery dramatically more accurate by allowing surgeons to distinguish -- at a microscopic level -- between brain tissue and tumors.

5 Sep 2013

Taconic To Promote And Sell Medicyte Hepatocyte Products

...

4 Sep 2013

Researchers develop new opioid drug for chronic pain

A team of researchers led by Andrew Coop, PhD, professor and chair of the Department of Pharmaceutical Sciences at the University of Maryland School of Pharmacy, has developed a new opioid drug that shows great potential to advance treatment and improve quality of life for individuals living with chronic pain.

29 Aug 2013

Novel machine learning-based approach used to predict hepatotoxic potential of DNA drug

New classes of therapeutic antisense oligonucleotides can have toxic effects on the liver. A novel machine learning-based approach used to predict the hepatotoxic potential of an antisense drug based on its chemical sequence is presented in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

28 Aug 2013

New compound offers way to treat migraine and other disorders of central nervous system

For many migraine sufferers, bright lights are a surefire way to exacerbate their headaches. And for some night-shift workers, just a stroll through a brightly lit parking lot during the morning commute home can be enough to throw off their body's daily rhythms and make daytime sleep nearly impossible. But a new molecule that selectively blocks specialized light-sensitive receptors in the eyes could help both these groups of people, without affecting normal vision.

28 Aug 2013

Sangamo BioSciences signs definitive agreement to buy Ceregene

Sangamo BioSciences, Inc. announced that it signed a definitive agreement to acquire Ceregene, Inc., a privately held biotechnology company focused on developing adeno-associated virus gene therapies.

26 Aug 2013

Seven researchers to receive grants from ASTRO to advance radiation oncology research

The American Society for Radiation Oncology (ASTRO) has selected seven (7) leading researchers who will receive a total of $675,000 in awards and grants to advance radiation oncology research.

23 Aug 2013

in vivo News and Research

Prairie Technologies acquired by Bruker

CardioExcyte 96 for cardiac toxicity profiling and screening introduced by Nanion

High resolution of U‐SPECT/CT system helps perform kinetic analyses of viral spread in vivo

Wake Forest Baptist conducts $24 million project to accelerate development of new therapies

arGEN-X generates potent antibody antagonists of Nav1.7 using SIMPLE Antibody technology

Exposing young girls to ionizing radiation can raise risk of breast cancer later in life

North Carolina professor receives 2013 New Scholar in Aging Award from Ellison Medical Foundation

Umbilical cord mesenchymal stem cells may have targeting capacity for glioma

Scientists use nanodiamonds to boost delivery of drug to leukemic cells

Chemists Find New Way To Put The Brakes On Cancer

Researchers find key mechanism behind Alzheimer's disease

Non-adherent bone marrow cell-derived mesenchymal stem cells could differentiate into neuronal-like cells

FIBRO-TARGETS project aims to identify mechanisms involved in MIF, define therapeutic approaches

New laser-based tool could improve accuracy of brain tumor surgery

Taconic To Promote And Sell Medicyte Hepatocyte Products

Researchers develop new opioid drug for chronic pain

Novel machine learning-based approach used to predict hepatotoxic potential of DNA drug

New compound offers way to treat migraine and other disorders of central nervous system

Sangamo BioSciences signs definitive agreement to buy Ceregene

Seven researchers to receive grants from ASTRO to advance radiation oncology research

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News