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Woman's ovarian cycle plays an important role in her susceptibility to infection

A new research report in the Journal of Leukocyte Biology suggests that a woman's ovarian cycle plays an important role in her susceptibility to infection.

4 Jan 2012

The Scientist selects Aspect Imaging's M2 imaging platform as one of Top 10 Innovations of 2011

The Scientist today unveiled the Top 10 Innovations of 2011 and selected Aspect Imaging's M2™ compact high-performance MRI imaging system as one the winners of this award. The Scientist invited members of the life science community to submit descriptions of exciting tools that made an impact in research this year and asked a panel of expert judges to evaluate the technologies.

2 Jan 2012

New initiative to detect cancers in earliest stages inside cells

A team of cancer imaging experts at Johns Hopkins has embarked on a five-year research initiative to speed development of early diagnostic tests and new treatments for breast, prostate and other common cancers.

29 Dec 2011

Researchers evaluate role of Mediterranean diet ingredients in prevention of cell damage

The researchers evaluated the role of Mediterranean diet ingredients in the prevention and mitigation of cell damage.

23 Dec 2011

Researchers develop CAD-type tools to engineer RNA control systems

The computer assisted design (CAD) tools that made it possible to fabricate integrated circuits with millions of transistors may soon be coming to the biological sciences. Researchers at the U.S. Department of Energy (DOE)'s Joint BioEnergy Institute (JBEI) have developed CAD-type models and simulations for RNA molecules that make it possible to engineer biological components or "RNA devices" for controlling genetic expression in microbes.

23 Dec 2011

Optical imaging can visualize cultured cancer cells' response to particular drug

Many cancer therapies target specific proteins that proliferate on the outside of some cancer cells, but the therapies are imperfect and the cancer does not always respond. Since it is beneficial for doctors to know as soon as possible how a cancer is affected by treatment, researchers from Vanderbilt University are striving to design tests that assess treatment response rapidly, accurately, and cost-effectively.

21 Dec 2011

Researchers discover how spinning microparticles can direct neuron growth

Researchers at UC Irvine and The University of Texas at Arlington have discovered how spinning microparticles can direct the growth of nerve fiber, a discovery that could allow for directed growth of neuronal networks on a chip and improve methods for treating spinal or brain injuries.

21 Dec 2011

Short spiral-shaped proteins can efficiently deliver DNA segments to cells

Clinical gene therapy may be one step closer, thanks to a new twist on an old class of molecules. A group of University of Illinois researchers, led by professors Jianjun Cheng and Fei Wang, have demonstrated that short spiral-shaped proteins can efficiently deliver DNA segments to cells. The team published its work in the journal Angewandte Chemie.

16 Dec 2011

FDA approves modernized labeling for ViroPharma's Vancocin Capsules

ViroPharma Incorporated today announced the modernization of labeling for Vancocin (vancomycin hydrochloride, USP) Capsules made effective through the U.S. Food and Drug Administration's (FDA) approval of a supplemental new drug application.

15 Dec 2011

Researchers discover novel viral oncogenesis mechanism

Human tumor viruses contribute to 15-20% of human cancers worldwide. Kaposi's sarcoma herpesvirus (KSHV) is an etiological agent for Kaposi's sarcoma (KS) and two other rare lymphoproliferative malignancies. KS is the most common cancer in HIV-infected untreated individuals and remains a primary cause of cancer deaths in many subequatorial African countries as a result of the AIDS pandemic.

15 Dec 2011

H2S plays critical role in signaling pathway linked to Alzheimer's and Parkinson's

Something rotten never smelled so sweet. This is what members of a team of scientists at Cold Spring Harbor Laboratory (CSHL) are telling one another as they discuss a new finding they did not expect to make. They have discovered that hydrogen sulfide (H2S) - the flammable, highly toxic gas that we usually associate with the smell of rotten eggs in landfills and sewers - plays an important role in the regulation of a signaling pathway implicated in biological malfunctions linked to Alzheimer's and Parkinson's diseases, among others.

14 Dec 2011

NYUCI experts present latest research findings about hematologic cancers at 53rd ASH meeting

Experts from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, presented their latest research findings about hematologic cancers at the 53rd ASH Annual Meeting and Exposition held December 10-13, 2011 in San Diego, California.

14 Dec 2011

New substance can replace nucleoside thymidine in DNA biosynthesis

Interactions of biological macromolecules are the central bases of living systems. Biological macromolecules are synthesized in living cells by linking many small molecules together. Naturally occurring macromolecules include genetic materials (DNA) and proteins. A detailed understanding of the synthesis of these macromolecules in whole animals is a basic requirement for understanding biological systems, and for the development of new therapeutic strategies.

14 Dec 2011

Scientists identify A2bAR as possible new therapeutic target against atherosclerosis

Researchers from Boston University School of Medicine (BUSM) have identified for the first time the A2b adenosine receptor (A2bAR) as a possible new therapeutic target against atherosclerosis resulting from a diet high in fat and cholesterol.

13 Dec 2011

Synta's ganetespib shows potent in vitro and in vivo activity against multiple breast cancer types

Synta Pharmaceuticals Corp. Ganetespib shows potent in vitro and in vivo activity against multiple types of breast cancer including HER2-positive, ER/PR positive, triple-negative, and inflammatory breast cancer according to results presented at the San Antonio Breast Cancer Symposium.

13 Dec 2011

InVivo co-founder receives 2011 The Economist annual Innovation Award in Bioscience

InVivo Therapeutics Holdings Corp., a company focused on the development of groundbreaking technologies for the treatment of spinal cord injuries (SCI), today congratulates Robert S. Langer, Sc.D., InVivo co-founder and member of the Company's Scientific Advisory Board, for his selection as the recipient of the 2011 The Economist annual Innovation Award in Bioscience.

12 Dec 2011

Research assesses safety and efficacy of pre-operative transfusions, hydroxyurea therapy for SCD

Research assessing the safety and efficacy of hydroxyurea therapy in pediatric patients with sickle cell disease (SCD) and the use of pre-operative transfusions for patients with SCD who undergo low- and moderate-risk elective surgery will be presented today at the 53rd Annual Meeting of the American Society of Hematology.

12 Dec 2011

Research examines novel treatment techniques for hemophilia B, VTE

Bleeding and clotting disorders affect a large number of patients annually and, while accurate diagnosis is important, timely and effective treatment for these disorders is key, as they have the potential to quickly become life-threatening. Research examining novel treatment techniques for bleeding and clotting disorders will be presented today at the 53rd Annual Meeting of the American Society of Hematology.

12 Dec 2011

New cancer research findings presented at 53rd ASH annual meeting

Researchers from Seidman Cancer Center at University Hospitals (UH) Case Medical Center and Case Western Reserve University School of Medicine presented new research findings in 25 presentations this weekend at the 53rd Annual Meeting of the American Society of Hematology (ASH) at the San Diego Convention Center.

12 Dec 2011

Considering varying extent to which genes are turned on or off can help develop personalised, predictive medicines

The vast majority of genetic disorders (schizophrenia or breast cancer, for example) have different effects in different people. Moreover, an individual carrying certain mutations can develop a disease, whereas another one with the same mutations may not. This holds true even when comparing two identical twins who have identical genomes. But why does the same mutation have different effects in different individuals?

8 Dec 2011

in vivo News and Research

Woman's ovarian cycle plays an important role in her susceptibility to infection

The Scientist selects Aspect Imaging's M2 imaging platform as one of Top 10 Innovations of 2011

New initiative to detect cancers in earliest stages inside cells

Researchers evaluate role of Mediterranean diet ingredients in prevention of cell damage

Researchers develop CAD-type tools to engineer RNA control systems

Optical imaging can visualize cultured cancer cells' response to particular drug

Researchers discover how spinning microparticles can direct neuron growth

Short spiral-shaped proteins can efficiently deliver DNA segments to cells

FDA approves modernized labeling for ViroPharma's Vancocin Capsules

Researchers discover novel viral oncogenesis mechanism

H2S plays critical role in signaling pathway linked to Alzheimer's and Parkinson's

NYUCI experts present latest research findings about hematologic cancers at 53rd ASH meeting

New substance can replace nucleoside thymidine in DNA biosynthesis

Scientists identify A2bAR as possible new therapeutic target against atherosclerosis

Synta's ganetespib shows potent in vitro and in vivo activity against multiple breast cancer types

InVivo co-founder receives 2011 The Economist annual Innovation Award in Bioscience

Research assesses safety and efficacy of pre-operative transfusions, hydroxyurea therapy for SCD

Research examines novel treatment techniques for hemophilia B, VTE

New cancer research findings presented at 53rd ASH annual meeting

Considering varying extent to which genes are turned on or off can help develop personalised, predictive medicines

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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