neoplasia News and Research

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New suppository developed for treatment of cervical pre-cancer

Infection with the human papillomavirus (HPV) can lead to cervical cancer via a preliminary stage - that of cervical intraepithelial neoplasia (CIN). In Europe 205,000 women every year are affected by this condition, most of them are aged between 25 and 30 years. Since in many cases slight manifestations of the disease (CIN 1) heal spontaneously, mostly no treatment is given but self-healing monitored by means of rigorous and continuous check-ups.

29 May 2013

Individuals with MEN1 are at increased risk of developing neuroendocrine tumors

A mutation in a protein called menin causes a hereditary cancer syndrome called MEN1 (multiple endocrine neoplasia type 1).

25 Apr 2013

New, preference-based navigation intervention improves screening rates for colon cancer

A mailing or phone call to help patients get screened for colorectal cancer significantly increases their chances of actually getting tested, according to a study published in the January issue of Cancer Epidemiology, Biomarkers and Prevention by researchers at the Kimmel Cancer Center at Jefferson.

29 Jan 2013

Study to determine prevalence of abnormal anal cytology and HPV in at-risk women

A basic connection of statistics lead a researcher at Women & Infants Hospital of Rhode Island to question whether women should be screened for anal cancer during a regular visit to the gynecologist, and what technique is most effective.

18 Jan 2013

New method can visualize aging and tumor growth in real-time

In a study published in the January 18 issue of Cell, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center have developed a new method to visualize aging and tumor growth in mice using a gene closely linked to these processes.

18 Jan 2013

Study evaluates effectiveness of 3 commonly used screening methods among South African women

The best approach to detecting cervical cancer in HIV-positive women living in research limited countries such as those in Sub-Saharan Africa combines commonly used testing methods tailored to local levels of development and medical infrastructure, according to a study by researchers from and the University of Witwatersrand in South Africa and the University of North Carolina.

16 Jan 2013

‘PapGene’ test detects endometrial and ovarian cancers

Researchers have adapted the papanicolaou smear test currently used to detect cervical cancer so that it can be used to screen women for endometrial and ovarian cancers.

14 Jan 2013

Sexual revolution effect may be hiding true extent of HPV prevalence

Human papillomavirus infection in older women is commonly due to reactivation of latent disease rather than new infection, research indicates.

2 Jan 2013

Androgen deprivation therapies may have adverse effects in men with precancers

The use of androgen deprivation therapies to prevent precancerous prostate abnormalities developing into aggressive prostate cancer may have adverse effects in men with precancers with specific genetic alterations, according to data from a preclinical study recently published in Cancer Discovery, a journal of the American Association for Cancer Research.

21 Dec 2012

HPV in women at or after menopause may represent an infection acquired years ago

A new study suggests that human papillomavirus (HPV) infection in women at or after menopause may represent an infection acquired years ago, and that HPV infections may exist below limits of detection after one to two years, similar to other viruses, such as varicella zoster, which can cause shingles.

14 Dec 2012

Pharmacological stress echo can identify rejected hearts suitable for transplantation

Hearts previously rejected due to donors' age or other risk factors can now be declared viable for transplantation using pharmacological stress echo, according to research presented at EUROECHO and other Imaging Modalities 2012.

5 Dec 2012

Infrared therapy could help prevent anal cancer in HIV-positive population

Infrared coagulopathy treatment of a potential precursor of anal cancer is effective and warrants further study as a way to reduce anal cancer incidence and mortality among HIV-infected people, report researchers.

30 Nov 2012

Ocular sebaceous carcinoma rare, but often misdiagnosed in UK

Ocular sebaceous carcinoma is rare in the UK, say researchers in the British Journal of Ophthalmology.

8 Nov 2012

HPV testing and cervical screening: an interview with Dr Rosa Legood

Human papillomavirus is a virus that is transmitted through sexual contact. In most cases the virus is transient and causes no harm, however in some cases it can go on to cause pre-cancer lesions and cervical cancer.

7 Nov 2012

Cervical cancer risk remains high after CIN treatment

Women who undergo treatment for screening-detected cervical intraepithelial neoplasia are more than four times more likely to develop cervical cancer than women with normal smear tests, research suggests.

5 Nov 2012

HPV test of cure cheaper and more effective than cytology testing for women following pre-cervical cancer treatment

Testing women to see if they are cured of HPV (the virus that can cause genital warts and cervical cancer) following treatment for abnormal cells on the surface of the cervix is more effective and cheaper than cytology testing (cervical screening) alone, suggests a study published on bmj.com.

2 Nov 2012