p53 Protein News and Research

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The TP53 is a gene that instructs the cell to produce tumor protein (p53) ; a vital transcription factor and tumor suppressor. P53 is known as the “guardian of the genome” as it helps in regulating the cell cycle and acts as a tumor suppressor.
Removing accumulated mutant p53 protein regresses tumors, increases cancer survival

Removing accumulated mutant p53 protein regresses tumors, increases cancer survival

UC Davis researchers uncover complex relationship between p53 and Rbm38 proteins

UC Davis researchers uncover complex relationship between p53 and Rbm38 proteins

Study sheds new light on well-known mechanism required for immune response

Study sheds new light on well-known mechanism required for immune response

Researchers discover new function of body's most important tumor-suppressing protein

Researchers discover new function of body's most important tumor-suppressing protein

Study shows inactivation of p53 protein promotes cancer progression

Study shows inactivation of p53 protein promotes cancer progression

Chemoprevention and colon cancer: an interview with Dr. John Letterio, Case Western Reserve University School of Medicine

Chemoprevention and colon cancer: an interview with Dr. John Letterio, Case Western Reserve University School of Medicine

St. Jude analysis reveals how protein p53 triggers cancer cells to commit suicide

St. Jude analysis reveals how protein p53 triggers cancer cells to commit suicide

UAMS receives $1.8M grant to lead new treatments for herpes viruses and cancers

UAMS receives $1.8M grant to lead new treatments for herpes viruses and cancers

Alteration in tumor suppressor gene TP53 plays key role early in development of bone cancer

Alteration in tumor suppressor gene TP53 plays key role early in development of bone cancer

Researchers discover genetic function that helps "tumor suppressor" genes to prevent cancer

Researchers discover genetic function that helps "tumor suppressor" genes to prevent cancer

Studies aim to address urgent need to identify possible new methods for mesothelioma treatment

Studies aim to address urgent need to identify possible new methods for mesothelioma treatment

Findings establish gene as critical regulator of lung cancer tumor growth

Findings establish gene as critical regulator of lung cancer tumor growth

p53 and cancer research: an interview with Professor Sir David Lane, Scientific Director of the Ludwig Institute for Cancer Research

p53 and cancer research: an interview with Professor Sir David Lane, Scientific Director of the Ludwig Institute for Cancer Research

p53 restoration of function drug candidate: an interview with Dr. Wayne Danter, MD, FRCPC President and CEO of Critical Outcome Technologies

p53 restoration of function drug candidate: an interview with Dr. Wayne Danter, MD, FRCPC President and CEO of Critical Outcome Technologies

Tumor suppressor p53 inactivation and restoration: an interview with Dr. Xin Lu, Ludwig Institute for Cancer Research

Tumor suppressor p53 inactivation and restoration: an interview with Dr. Xin Lu, Ludwig Institute for Cancer Research

Study suggests possible way to halt cancer development in premalignant cells

Study suggests possible way to halt cancer development in premalignant cells

Inherited mutations in p53 gene put people at high risk of developing cancers

Inherited mutations in p53 gene put people at high risk of developing cancers

Mechanism of tumor suppressor p53 inactivation described

Mechanism of tumor suppressor p53 inactivation described

Researchers identify new mechanism in onset of motor neuron diseases

Researchers identify new mechanism in onset of motor neuron diseases

TP63 gene correlates significantly with worse prognosis of melanoma

TP63 gene correlates significantly with worse prognosis of melanoma