p53 Protein News and Research

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The TP53 is a gene that instructs the cell to produce tumor protein (p53) ; a vital transcription factor and tumor suppressor. P53 is known as the “guardian of the genome” as it helps in regulating the cell cycle and acts as a tumor suppressor.
Oncogenic RAS mutations are responsible for regrowth of cancer cells following genotoxic therapies

Oncogenic RAS mutations are responsible for regrowth of cancer cells following genotoxic therapies

Studies reveal the promise of newly engineered bispecific antibodies against tumor cells

Studies reveal the promise of newly engineered bispecific antibodies against tumor cells

Study opens the way for a potential new cure for children with hard-to-treat neuroblastoma

Study opens the way for a potential new cure for children with hard-to-treat neuroblastoma

Tumor suppressor gene represses 'jumping genes'

Tumor suppressor gene represses 'jumping genes'

Antioxidants in diet could raise risk of bowel cancer, new study reveals

Antioxidants in diet could raise risk of bowel cancer, new study reveals

Rare inherited mutation in TP53 gene confers risk of multiple cancers

Rare inherited mutation in TP53 gene confers risk of multiple cancers

New insight into RNA movements can pave way for strategies to treat cancer

New insight into RNA movements can pave way for strategies to treat cancer

Study shows how cancer protein changes may accelerate tumorigenesis and metastasis

Study shows how cancer protein changes may accelerate tumorigenesis and metastasis

New study expands the knowledge on tumor-suppressor role of HERC proteins

New study expands the knowledge on tumor-suppressor role of HERC proteins

Scientists pinpoint protein that plays key role in lung cancer and melanoma progression

Scientists pinpoint protein that plays key role in lung cancer and melanoma progression

Iron overload, variant gene and malaria resistance linked in African study

Iron overload, variant gene and malaria resistance linked in African study

p53 may play a more important role in kidney cancer than previously thought

p53 may play a more important role in kidney cancer than previously thought

Jefferson researcher probes kidney cancer's genes for interactions with p53 pathway

Jefferson researcher probes kidney cancer's genes for interactions with p53 pathway

Researchers identify chemical compounds that increase stability of haploid cell

Researchers identify chemical compounds that increase stability of haploid cell

New spectroscopic approach investigates difficult-to-observe protein structures

New spectroscopic approach investigates difficult-to-observe protein structures

Small molecule drug could be an effective strategy to treat glioblastoma

Small molecule drug could be an effective strategy to treat glioblastoma

Study finding promises new perspectives for treatment of Type 2 endometrial cancer

Study finding promises new perspectives for treatment of Type 2 endometrial cancer

Synthetic compound reverses mutant p53 aggregate accumulation, study shows

Synthetic compound reverses mutant p53 aggregate accumulation, study shows

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Loss of tumor protein p53 helps cancer cells grow in hostile environment

Loss of tumor protein p53 helps cancer cells grow in hostile environment