siRNA News and Research

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Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA molecules, 20-25 nucleotides in length, that play a variety of roles in biology. Most notably, siRNA is involved in the RNA interference (RNAi) pathway, where it interferes with the expression of a specific gene. In addition to their role in the RNAi pathway, siRNAs also act in RNAi-related pathways, e.g., as an antiviral mechanism or in shaping the chromatin structure of a genome; the complexity of these pathways is only now being elucidated.
Peptide-based nanoparticles can suppress pancreatic cancer growth without adverse effects

Peptide-based nanoparticles can suppress pancreatic cancer growth without adverse effects

Common gout medications can kill elephantiasis-causing parasites

Common gout medications can kill elephantiasis-causing parasites

New platform uses nanoparticles to deliver anti-cancer agent to cells

New platform uses nanoparticles to deliver anti-cancer agent to cells

Researchers identify new transmembrane protein as chloride ion channel

Researchers identify new transmembrane protein as chloride ion channel

Newborn mouse model yields clues to cause of devastating gut disease in anemic preemies

Newborn mouse model yields clues to cause of devastating gut disease in anemic preemies

A non-coding RNA may play major role in memory formation

A non-coding RNA may play major role in memory formation

Investigating RNA-based regulation of the cardiovascular system

Investigating RNA-based regulation of the cardiovascular system

Low-dose radiation therapy may increase uptake of therapeutic nanoparticles by brain tumors

Low-dose radiation therapy may increase uptake of therapeutic nanoparticles by brain tumors

Researchers outline targeted therapeutic strategy for triple-negative breast cancer

Researchers outline targeted therapeutic strategy for triple-negative breast cancer

A new treatment for Chlamydia via Canadian researchers

A new treatment for Chlamydia via Canadian researchers

Researchers develop new way to prevent and treat Chlamydia

Researchers develop new way to prevent and treat Chlamydia

Lab model reveals the formation of new blood vessels

Lab model reveals the formation of new blood vessels

From Our Bench to Yours: Antibody Advice from Proteintech

From Our Bench to Yours: Antibody Advice from Proteintech

RNAi therapy shown to alleviate preeclampsia in animal model

RNAi therapy shown to alleviate preeclampsia in animal model

Combination therapy enhances wound healing

Combination therapy enhances wound healing

Alnylam announces positive results from Phase 1/2 study of lumasiran for treating primary hyperoxaluria-1

Alnylam announces positive results from Phase 1/2 study of lumasiran for treating primary hyperoxaluria-1

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Alnylam reports further progress on broadening the therapeutic potential of RNAi

Alnylam reports further progress on broadening the therapeutic potential of RNAi

Alnylam announces positive results from Phase 3 Study of givosiran for treating acute hepatic porphyria

Alnylam announces positive results from Phase 3 Study of givosiran for treating acute hepatic porphyria

Antioxidant in green tea helps sneak therapeutic RNAs into cells

Antioxidant in green tea helps sneak therapeutic RNAs into cells