siRNA News and Research

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Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA molecules, 20-25 nucleotides in length, that play a variety of roles in biology. Most notably, siRNA is involved in the RNA interference (RNAi) pathway, where it interferes with the expression of a specific gene. In addition to their role in the RNAi pathway, siRNAs also act in RNAi-related pathways, e.g., as an antiviral mechanism or in shaping the chromatin structure of a genome; the complexity of these pathways is only now being elucidated.
Nanotechnology and COVID-19 diagnosis and treatment

Nanotechnology and COVID-19 diagnosis and treatment

Using ultrasound and RNA-loaded nanoparticles to deliver potent medicine to brain tumors

Using ultrasound and RNA-loaded nanoparticles to deliver potent medicine to brain tumors

Interfering RNA nanoparticles could be a potential COVID-19 therapy

Interfering RNA nanoparticles could be a potential COVID-19 therapy

Topical drug regenerates, restores function of erectile nerves damaged by radical prostatectomy

Topical drug regenerates, restores function of erectile nerves damaged by radical prostatectomy

Changes in OASI gene expression increases risk of Alzheimer's and severe COVID-19 infection

Changes in OASI gene expression increases risk of Alzheimer's and severe COVID-19 infection

Scientists develop RNA-based therapeutic strategy for Charcot-Marie Tooth disease

Scientists develop RNA-based therapeutic strategy for Charcot-Marie Tooth disease

Study identifies potential therapeutic target for non-alcoholic fatty liver disease

Study identifies potential therapeutic target for non-alcoholic fatty liver disease

mRNA Therapeutics – Analytical and Bioanalytical Characterization

mRNA Therapeutics – Analytical and Bioanalytical Characterization

Researchers develop ultra-small nanomedicines to target intractable cancers

Researchers develop ultra-small nanomedicines to target intractable cancers

Researchers use aerosolized molecules to shut down proteins generated by coronavirus

Researchers use aerosolized molecules to shut down proteins generated by coronavirus

Novel super-activating macrophage receptor could explain hyper-inflammation in severe COVID-19

Novel super-activating macrophage receptor could explain hyper-inflammation in severe COVID-19

Antiviral inhibitor DDX42 shows broad activity against Chikungunya, HIV and SARS-CoV-2

Antiviral inhibitor DDX42 shows broad activity against Chikungunya, HIV and SARS-CoV-2

Researchers find a new therapeutic approach to combat leukemia

Researchers find a new therapeutic approach to combat leukemia

Design of an mRNA SARS-CoV-2 vaccine encapsulated in lipid nanoparticles

Design of an mRNA SARS-CoV-2 vaccine encapsulated in lipid nanoparticles

Researchers develop new strategy to improve siRNA stability

Researchers develop new strategy to improve siRNA stability

SARS-CoV-2 hijacks antiviral factors to promote infection in human lung cells

SARS-CoV-2 hijacks antiviral factors to promote infection in human lung cells

Potential inhibitors of SARS-CoV-2 identified

Potential inhibitors of SARS-CoV-2 identified

siRNA-based treatment can reduce psoriasis symptoms

siRNA-based treatment can reduce psoriasis symptoms

siRNA therapeutics can reduce off-target side effects of anticancer drugs

siRNA therapeutics can reduce off-target side effects of anticancer drugs

Scientists discover promising therapy to combat the growing epidemic of liver disease

Scientists discover promising therapy to combat the growing epidemic of liver disease