siRNA News and Research

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Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA molecules, 20-25 nucleotides in length, that play a variety of roles in biology. Most notably, siRNA is involved in the RNA interference (RNAi) pathway, where it interferes with the expression of a specific gene. In addition to their role in the RNAi pathway, siRNAs also act in RNAi-related pathways, e.g., as an antiviral mechanism or in shaping the chromatin structure of a genome; the complexity of these pathways is only now being elucidated.
New model pinpoints drug interactions in the digestive tract

New model pinpoints drug interactions in the digestive tract

Researchers develop novel nanomedicine loaded with genetic material to fight  HIV

Researchers develop novel nanomedicine loaded with genetic material to fight HIV

Novel splicing mechanism for short introns discovered

Novel splicing mechanism for short introns discovered

MIT scientists develop nanoparticles to reduce inflammation in the brain

MIT scientists develop nanoparticles to reduce inflammation in the brain

Silencing galectin 1 protein shrinks liver cancer tumors in mice

Silencing galectin 1 protein shrinks liver cancer tumors in mice

Study highlights YB-1 targeting as novel treatment approach for pleural mesothelioma

Study highlights YB-1 targeting as novel treatment approach for pleural mesothelioma

Discovery lead to better methods for reducing mosquito-to-human transmission of deadly viruses

Discovery lead to better methods for reducing mosquito-to-human transmission of deadly viruses

Unraveling the relationship between obesity-related metabolic dysfunction and endotrophin

Unraveling the relationship between obesity-related metabolic dysfunction and endotrophin

Study identifies potential target for reversing drug resistance in ovarian cancer

Study identifies potential target for reversing drug resistance in ovarian cancer

Amgen presents late-breaking Phase 2 olpasiran data at ESC 2023

Amgen presents late-breaking Phase 2 olpasiran data at ESC 2023

New insights into the role of liver progenitor cells in liver cancer initiation

New insights into the role of liver progenitor cells in liver cancer initiation

BUB1 protein and its kinase activity may regulate EGFR activation

BUB1 protein and its kinase activity may regulate EGFR activation

Revolution in neuroscience: 2D nanomaterials propel advances in brain repair, treatment, and diagnosis

Revolution in neuroscience: 2D nanomaterials propel advances in brain repair, treatment, and diagnosis

New technology can deliver gene therapy directly to the lung

New technology can deliver gene therapy directly to the lung

Researchers develop novel molecular nanocages for siRNA delivery

Researchers develop novel molecular nanocages for siRNA delivery

Unlocking the potential of RNA lipid nanoparticles to revolutionize cancer treatment

Unlocking the potential of RNA lipid nanoparticles to revolutionize cancer treatment

Monthly prophylactic fitusiran injections effective in reducing bleeds in patients with hemophilia A or B

Monthly prophylactic fitusiran injections effective in reducing bleeds in patients with hemophilia A or B

New review examines link between HDLC and different types of cancer

New review examines link between HDLC and different types of cancer

Decades of substantial U.S. Government investment in mRNA technology paved way for COVID-19 vaccines

Decades of substantial U.S. Government investment in mRNA technology paved way for COVID-19 vaccines