siRNA News and Research

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Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA molecules, 20-25 nucleotides in length, that play a variety of roles in biology. Most notably, siRNA is involved in the RNA interference (RNAi) pathway, where it interferes with the expression of a specific gene. In addition to their role in the RNAi pathway, siRNAs also act in RNAi-related pathways, e.g., as an antiviral mechanism or in shaping the chromatin structure of a genome; the complexity of these pathways is only now being elucidated.
Researchers win $1.4 million federal grant to study new treatment approaches for intestinal inflammation

Researchers win $1.4 million federal grant to study new treatment approaches for intestinal inflammation

Study demonstrates potential nanoparticle-based therapeutic strategy for deadly brain tumors

Study demonstrates potential nanoparticle-based therapeutic strategy for deadly brain tumors

Genetic manipulation of exosomes may offer new therapeutic approach to treating pancreatic cancer

Genetic manipulation of exosomes may offer new therapeutic approach to treating pancreatic cancer

Leti's New Deal project could revolutionize IBD therapies for great benefit of patients in the European Union

Leti's New Deal project could revolutionize IBD therapies for great benefit of patients in the European Union

Study reveals potential therapeutic target for kidney fibrosis

Study reveals potential therapeutic target for kidney fibrosis

Single dose of siRNA molecule offers protection against heart attack and stroke in high-risk patients

Single dose of siRNA molecule offers protection against heart attack and stroke in high-risk patients

Scientists reveal novel drug delivery approach to fight swine flu at gene level

Scientists reveal novel drug delivery approach to fight swine flu at gene level

Scientists identify genetic clues to chronic kidney disease

Scientists identify genetic clues to chronic kidney disease

Precision NanoSystems launches NanoAssemblr Scale-Up system to support production of novel medicines

Precision NanoSystems launches NanoAssemblr Scale-Up system to support production of novel medicines

Using spherical nucleic acids to track and treat disease

Using spherical nucleic acids to track and treat disease

Glowing mice could mark major step forward for new gene therapy

Glowing mice could mark major step forward for new gene therapy

Reseachers identify cellular ‘off’ switch for inflammatory immune response in asthma attacks

Reseachers identify cellular ‘off’ switch for inflammatory immune response in asthma attacks

New treatment with therapeutic short interfering RNA could help thwart cancer

New treatment with therapeutic short interfering RNA could help thwart cancer

Nanoparticle injections may help prevent cartilage degeneration in osteoarthritis patients

Nanoparticle injections may help prevent cartilage degeneration in osteoarthritis patients

KAUST researchers develop biocompatible nanostructures for use in gene delivery

KAUST researchers develop biocompatible nanostructures for use in gene delivery

Scientists engineer therapeutic system with two arms to get better hold on cancer target

Scientists engineer therapeutic system with two arms to get better hold on cancer target

Overcoming gene silencing barriers to target neurological conditions: an interview with Dr Errol de Souza

Overcoming gene silencing barriers to target neurological conditions: an interview with Dr Errol de Souza

New topical film patch can effectively close dermal wounds, reduce scarring

New topical film patch can effectively close dermal wounds, reduce scarring

Alnylam reports new results from investigational RNAi therapeutic programs

Alnylam reports new results from investigational RNAi therapeutic programs

Researchers develop novel ss-siRNAs to turn off disease-related genes

Researchers develop novel ss-siRNAs to turn off disease-related genes