SuperC18 UHPLC Column from ACE

The unique Encapsulated Bonding Technology (EBT™) developed for ACE SuperC18 columns dramatically increases ligand coverage of the silica surface and effectively  eliminates the effect of unbonded silanol groups from separations. This higher ligand coverage results in improved inertness, chromatographic performance and stability.

Under aggressive acidic conditions ACE SuperC18 is highly resistant to ligand cleavage, due to a combination of the Encapsulated Bonding Technology  (EBT™) and ultra-inert ACE silica. Many C18 bonded columns will exhibit ligand cleavage under acidic conditions, resulting in retention shifts and/or increased peak  tailing.


  • Exploit selectivity at low, intermediate and high pH
  • Use with LC/MS compatible buffers between pH 1.5 – 11.5
  • High efficiency 2μm, 3μm, 5μm and 10μm particles for UHPLC and HPLC
  • Ultra-inert for maximum performance and reproducibility