X-CLARITY™ Tissue Clearing System II

The X-CLARITY™ Tissue Clearing System II is an all-in-one, easy-to-use solution for electrophoretic tissue clearing system. Its unique design accelerates the removal of lipids from tissues while preserving the structural integrity of the sample.

Users can set tissue clearing conditions through a simple and intuitive touchscreen interface. In ETC (electrophoretic tissue clearing) mode, platinum-plated electrodes generate an electric field to accelerate the removal of lipids from tissues in a highly efficient manner.

A built-in temperature control system actively cools and heats buffer to maintain consistent buffer temperatures during clearing. Buffer is constantly circulated to ensure consistent buffering capacity, temperature control, and elimination of tissue clearing byproducts. This advanced system ensures efficient, rapid, and consistent tissue clearing.


Precise temperature control

  • Active buffer cooling and heating capacity
  • Sensitive and accurate temperature sensor

Uniform electric field

  • Platinum-plated electrodes
  • Constant current and constant voltage modes

Compatible with multiple tissue types and sizes

  • Electrophoretic and passive clearing
  • Holders of various sizes available

User-friendly setup

  • Simple touchscreen interface
  • Ready-to-use clearing solution

Compatible sample holders

X-CLARITY™ ETC Chamber Specifications

Instrument Type Electrophoretic chamber
External dimensions (W x D x H) 176 mm x 128 mm x 154 mm
Inernal dimensions (W x D x H) 57 mm x 30 mm x 93 mm
Weight 2.8 kg

X-CLARITY™ ETC Control Tower Specifications

Instrument Type Power supply, temperature control, and buffer circulation device
User interface 5 inch TFT LCD touchscreen
Power supply modes Constant current or constant voltage
Current & voltage range 0.2-1.5 A, 5-70 V
Temperature range 30-60° C
Pump speed range 50-200 rpm
Electrical requirements AC 100-240 V, 50/60 Hz
Power consumption 500 W (including the X-CLARITY™ ETC Chamber)
Dimensions (W x D x H) 205 mm x 430 mm x 370 mm
Weight 20 kg

Long-term preservation of the Thy1-YFP signal in tissues cleared with the X-CLARITY™ systems and reagents. (A) Thy1-YFP signal immediately after clearing. (B) Thy1-YFP signal one month after clearing.

Thy1-YFP mouse brain slices cleared with the X-CLARITY™ systems and reagents. Thy1-YFP (green), Anti-Collagen IV (red), TO-PRO-3 (blue).

Verified with multiple tissue types