Gene News and Research

Latest Gene News and Research

Researchers identify genes linked to most severe symptoms of multiple sclerosis

In a bid to determine factors linked to the most debilitating forms of multiple sclerosis, Johns Hopkins Medicine researchers say they have identified three so-called "complement system" genes that appear to play a role in MS-caused vision loss.

From Johns Hopkins Medicine 31 Oct 2019

Novel method for aggressive breast cancer detection

A new study in rats published in the journal Cell Reports shows that the pattern of RNA molecules produced within certain immune cells called macrophages, found within breast cancers (tumor-associated macrophages, TAMs), can tell whether the tumor is cancerous or not and indicate the type of outcome. The same pattern is present in humans as in mice. This makes it directly useful in predicting the nature of a breast tumor and its outcome.

30 Oct 2019

Researchers develop new therapeutic concept for treatment of temporal lobe epilepsy

Teams of researchers from Charité - Universitätsmedizin Berlin and the Medical University of Innsbruck have developed a new therapeutic concept for the treatment of temporal lobe epilepsy.

30 Oct 2019

New way to slow and reverse fibrosis identified

In cell and mouse models, Mayo Clinic researchers and collaborators have identified a way to slow and reverse the process of uncontrolled internal scarring, called fibrosis.

30 Oct 2019

Education may erase risk of cognitive decline linked to APOE e4 gene in black people

Education may erase the risk of cognitive decline associated with the APOE e4 gene--the biggest genetic risk factor for late-onset Alzheimer's disease--in older non-Hispanic black people, according to a new study by researchers at Columbia University Vagelos College of Physicians and Surgeons.

30 Oct 2019

Key gene mutated in familial Alzheimer's regulates differentiation of neurons

An international team of researchers led by the Institute of Neuroscience at the Universitat Autònoma de Barcelona describes a new route that promotes differentiation of neurons.

30 Oct 2019

Scientists receive $1.6 million grant to study impact of phthalate exposure on male fertility

A cross-disciplinary team of scientists, led by University of Massachusetts Amherst environmental epigeneticist Richard Pilsner, will use a three-year, $1.6 million grant from the National Institute of Environmental Health Sciences to expand research into the impact of phthalate exposure on male fertility.

30 Oct 2019

Researchers develop new leucocyte markers

An article entitled "Human Peripheral Blood Eosinophils Express High Levels of the Purinergic Receptor P2X4" written by an international immunology research group was recently published in the scientific journal Frontiers in Immunology.

30 Oct 2019

NTU study: Microorganisms show a precise daily rhythm in tropical air

Scientists from the Singapore Centre for Environmental Life Sciences Engineering at Nanyang Technological University, Singapore have found that the air in the tropics is teeming with a rich and diverse range of at least 725 different microorganisms.

30 Oct 2019

Researchers use AI to identify RNA binding sites on proteins

Researchers have developed an artificial intelligence (AI) tool that can accurately detect which sites on the surface of a protein bind to RNA molecules.

30 Oct 2019

Scientists modify a toxic protein to create a biosensor

Researchers have shown that the pore-forming toxin (PFT), aerolysin, could be used as a biosensor in the sequencing of DNA and proteins.

30 Oct 2019

Improved Cas9 enzyme reduces chance of off-target CRISPR mutations

Genomics experts have discovered that when guide RNAs (gRNA) are designed properly, the risk of off-target mutations induced by the cas9 enzyme is very rare.

30 Oct 2019

New collaborative effort focuses on therapeutic research for CDKL5 Deficiency Disorder

CDKL5 Deficiency Disorder is a devastating neurodevelopmental disorder caused by mutations in the CDKL5 gene.

30 Oct 2019

Chemotherapy-induced senescent cells eat neighboring cells

A new study has found that chemotherapy-induced senescent cancer cells feed on other neighboring cells to enhance their survival.

30 Oct 2019

Novel, cost-effective method successfully identifies aggressive tumors

Researchers have developed a novel, cost-effective genomic method that can identify highly heterogenous tumors that are typically aggressive in nature.

30 Oct 2019

TDP-43 study could speed up the diagnosis and treatment of ALS

A new study suggests that TDP-43 may be used as a biomarker in the diagnosis and treatment of amyotrophic lateral sclerosis (ALS).

30 Oct 2019

Study: MIB2 improves inflammation by degrading CYLD enzyme

The tumor suppressor CYLD lysine 63 deubiquitinase (CYLD) is a deubiquitinating enzyme that suppresses polyubiquitin-dependent signaling pathways, including the proinflammatory and cell growth-promoting NF-κB pathway.

30 Oct 2019

IU researcher receives NIH grant to perform clinical trial on cirrhosis

An Indiana University School of Medicine researcher has been awarded a five-year, $1.8 million grant from the National Institutes of Health for a clinical trial, aimed at providing new avenues to improve liver function for patients with alcoholic cirrhosis.

30 Oct 2019

DNA sequences encode information in many different ways

DNA sequences encode information in many different ways. Codons specify the amino acids involved in making a protein.

30 Oct 2019

Brain function changes could help diagnose and manage depression

Ever heard of the lateral habenula? Very few, outside of neuroscience, probably have. Yet a new study, published in the journal Neuron, shows that characteristic changes in the way this area of the brain fires can result in a total loss of will to do anything – which is characteristic of one form of depression.

29 Oct 2019