Gene News and Research

Latest Gene News and Research

A new method to deliver therapeutic proteins inside the body

A new way to deliver therapeutic proteins inside the body uses an acoustically sensitive carrier to encapsulate the proteins and ultrasound to image and guide the package to the exact location required, according to Penn State researchers. Ultrasound then breaks the capsule, allowing the protein to enter the cell.

23 Apr 2020

Meis1 protein plays key role in stopping cell division in the heart

UT Southwestern Medical Center scientists have discovered a protein that works with others during development to put the brakes on cell division in the heart, they report today in Nature.

23 Apr 2020

Study: Patients’ genetically edited stem cells successfully reversed diabetes in mice

Using induced pluripotent stem cells produced from the skin of a patient with a rare, genetic form of insulin-dependent diabetes called Wolfram syndrome, researchers transformed the human stem cells into insulin-producing cells and used the gene-editing tool CRISPR-Cas9 to correct a genetic defect that had caused the syndrome.

22 Apr 2020

Study creates a new platform to study single-cell genomics of many diseases

Although advances in genetics and genomics reveal numerous disease-associated gene mutations, physicians and researchers still wrestle with the tricky challenge of linking those mutations to actual disease-causing processes.

22 Apr 2020

Scientists identify cells likely targeted by novel coronavirus

Researchers at MIT; the Ragon Institute of MGH, MIT, and Harvard; and the Broad Institute of MIT and Harvard; along with colleagues from around the world have identified specific types of cells that appear to be targets of the coronavirus that is causing the Covid-19 pandemic.

22 Apr 2020

Study shows why depression affects women more than men

Researchers at Mount Sinai have found that a novel class of genes known as long non-coding RNAs (lncRNAs) expressed in the brain may play a pivotal role in regulating mood and driving sex-specific susceptibility versus resilience to depression.

22 Apr 2020

Scientists find gene signature for poor response to standard therapy in rare uterine cancer

Women who don't survive a rare and aggressive uterine cancer called uterine serous carcinoma, have high expression of a group of 73 genes, a score scientists say can help identify these women and improve their outcome.

22 Apr 2020

Researchers uncover how cancer cells don their invisibility cloaks

Immunotherapy drugs that target a protein called programmed death ligand 1 (PD-L1) on the surface of cancer cells have quickly become a mainstay to treat many forms of cancer, often with dramatic results. But exactly how cancer cells turn on this protein was not completely understood.

22 Apr 2020

Slightly elevated blood glucose levels can trigger major changes in insulin-producing cells

In diabetes, tiny clusters of insulin-producing "beta cells" in the pancreas don't produce enough of the hormone to keep people healthy, and their blood glucose levels climb.

22 Apr 2020

Research offers clues to how SARS-CoV-2 gets into respiratory tissue and exploits our defenses

What makes SARS-CoV-2, the virus behind COVID-19, such a threat? A new study, led by Jose Ordovas-Montanes, Ph.D. at Boston Children's Hospital and Alex K. Shalek, Ph.D. at MIT, pinpoints the likely cell types the virus infects.

22 Apr 2020

Study reveals surprising findings on gene involved in human pregnancy

From an evolutionary perspective, human pregnancy is quite strange, says University at Buffalo biologist Vincent Lynch.

22 Apr 2020

Gene therapy could help treat glaucoma, study shows

A new study led by the University of Bristol has shown a common eye condition, glaucoma, could be successfully treated with a single injection using gene therapy, which would improve treatment options, effectiveness and quality of life for many patients.

21 Apr 2020

Age-related DNA modifications linked with susceptibility to eye disease

National Eye Institute researchers profiling epigenomic changes in light-sensing mouse photoreceptors have a clearer picture of how age-related eye diseases may be linked to age-related changes in the regulation of gene expression.

21 Apr 2020

Study finds how metabolism regulates sleep in worms

Can staying up late make you fat? A growing body of research has suggested that poor sleep quality is linked to an increased risk of obesity by deregulating appetite, which in turn leads to more calorie consumption.

21 Apr 2020

AI may help eliminate use of biopsy for brain cancer patients

Brain cancer patients in the coming years may not need to go under the knife to help doctors determine the best treatment for their tumors.

21 Apr 2020

Study: Behavioral intervention is effective in treating language problems in youth with FXS

A UC Davis Health study found more evidence for the efficacy of telehealth-delivered behavioral intervention in treating language problems in youth with fragile X syndrome (FXS).

21 Apr 2020

NEI researchers link age-related DNA modifications to susceptibility to eye disease

Researchers profiling epigenomic changes in mouse photoreceptors suggest that age-related eye diseases may be linked to gene expression.

21 Apr 2020

Antibodies against Imood could be potential treatment for OCD

Mental health conditions such as obsessive compulsive disorder could be treated in a new way using drugs that target the immune system, research suggests.

21 Apr 2020

Advanced paternal age associated with risk of neurodevelopmental disorders in children

It is no secret that genetic factors play a role in determining whether children have neurodevelopmental disorders. Maternal exposure to drugs and viral or bacterial illnesses can be detrimental too.

21 Apr 2020

Study shows why MDS cells have a competitive advantage that supports disease progression

A powerful clue has emerged in a long-running mystery about how the cells of myelodysplastic syndrome (MDS) manage to outcompete normal blood cells to cause a disease state that often leads to leukemia, according to a study published online April 20, 2020, in Nature Immunology.

21 Apr 2020

Gene News and Research

Latest Gene News and Research

A new method to deliver therapeutic proteins inside the body

Meis1 protein plays key role in stopping cell division in the heart

Study: Patients’ genetically edited stem cells successfully reversed diabetes in mice

Study creates a new platform to study single-cell genomics of many diseases

Scientists identify cells likely targeted by novel coronavirus

Study shows why depression affects women more than men

Scientists find gene signature for poor response to standard therapy in rare uterine cancer

Researchers uncover how cancer cells don their invisibility cloaks

Slightly elevated blood glucose levels can trigger major changes in insulin-producing cells

Research offers clues to how SARS-CoV-2 gets into respiratory tissue and exploits our defenses

Study reveals surprising findings on gene involved in human pregnancy

Gene therapy could help treat glaucoma, study shows

Age-related DNA modifications linked with susceptibility to eye disease

Study finds how metabolism regulates sleep in worms

AI may help eliminate use of biopsy for brain cancer patients

Study: Behavioral intervention is effective in treating language problems in youth with FXS

NEI researchers link age-related DNA modifications to susceptibility to eye disease

Antibodies against Imood could be potential treatment for OCD

Advanced paternal age associated with risk of neurodevelopmental disorders in children

Study shows why MDS cells have a competitive advantage that supports disease progression

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