Gene News and Research

Latest Gene News and Research

Study highlights need for population-specific precision medicine programs in Latin America

Drug safety and effectiveness vary greatly among populations worldwide. Genetics is one of the factors that contribute to variability in drug response.

3 Oct 2018

Carnegie professor receives NIH Director's New Innovator Award

Kathryn Whitehead, assistant professor of chemical engineering at Carnegie Mellon University, has been awarded a 2018 National Institutes of Health (NIH) Director's New Innovator Award for her project titled "Fate, Function, and Genetic Engineering of Breast Milk Cells for Infant Therapy."

3 Oct 2018

Some people can avoid depression by maintaining serotonin level throughout the year

Some people can adjust to environmental stressors to avoid depression. Women need to do this more than men to avoid getting depressed.

3 Oct 2018

Alnylam reports further progress on broadening the therapeutic potential of RNAi

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today further progress on the Company's platform efforts in extrahepatic delivery of novel siRNA conjugates, including central nervous system (CNS) and ocular delivery in rat and non-human primates (NHPs).

3 Oct 2018

Study: Phyloplankton's ability to generate resting stages plays key role in genetic differences

The genetic differences in phyloplankton living in close geographic proximity can be great, something which long has surprised researchers. Now new research shows that the ability of phyloplankton to generate resting stages can be an important part of the explanation.

1 Oct 2018

Study finds disease-causing mutation in French-Canadians

A team of Canadian scientists, including researchers at the Montreal Neurological Institute and Hospital has discovered the first French-Canadian founder mutation gene linked to synucleinopathies, a group of neurodegenerative diseases that includes Parkinson's disease, dementia with Lewy-Bodies and multiple system atrophy

1 Oct 2018

Genetic variants reveal novel therapeutic targets for chronic kidney disease

The kidney does more than double or even triple duty compared to other organs - it extracts waste, balances body fluids, forms urine, regulates blood pressure, and secretes hormones.

1 Oct 2018

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

A specific protein called TEAD1 is an important regulator of tumor migration in glioblastoma, the most common brain tumor in adults, and deactivating this protein may stop tumor cells from migrating away from the main tumor mass, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 1 in the journal Nature Communications.

1 Oct 2018

'Kidney-gene' plays role in the central nervous system and controls movement

The WT1 gene fulfills a central role in the development of a healthy, proper functioning kidney. Mutations in WT1 lead to impairments in kidney development and cause Wilms tumors, a pediatric kidney cancer.

1 Oct 2018

FDA permits marketing of ClonoSEQ assay to detect minimal residual disease in blood cancer patients

Today the U.S. Food and Drug Administration permitted marketing of ClonoSEQ assay, a next generation sequencing-based test for minimal residual disease in patients with acute lymphoblastic leukemiaor multiple myeloma. MRD is a measure of the amount of cancer cells remaining in a person's bone marrow.

30 Sep 2018

Researchers deplete key protein for DNA replication using protein degradation system

Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein degradation system.

29 Sep 2018

Researchers design new combination therapy for reducing NSCLC cell growth

Lung cancer is the leading cause of cancer death among men and women. About 85 percent of lung cancers are non-small cell lung cancer. For a handful of these patients, therapies that target specific genetic mutations are effective.

29 Sep 2018

Engineering organoids from stem cells to model retina diseases

Gray Camp joined the Institute of Molecular and Clinical Ophthalmology Basel as Group Leader in Single Cell Genomics. His group will combine single-cell genomic tools and retina and cerebral "organoids" to explore the development of the human visual system.

28 Sep 2018

Australian scientists resolve a key question in ovarian cancer care

Australian scientists have revealed a better way to identify which patients should respond to powerful ovarian cancer drugs called PARP inhibitors (PARPi), resolving an important question in ovarian cancer care about why some patients respond to these drugs, while others do not.

28 Sep 2018

Gene News and Research

Latest Gene News and Research

Study highlights need for population-specific precision medicine programs in Latin America

Carnegie professor receives NIH Director's New Innovator Award

Some people can avoid depression by maintaining serotonin level throughout the year

Alnylam reports further progress on broadening the therapeutic potential of RNAi

Study: Phyloplankton's ability to generate resting stages plays key role in genetic differences

Study finds disease-causing mutation in French-Canadians

Genetic variants reveal novel therapeutic targets for chronic kidney disease

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

'Kidney-gene' plays role in the central nervous system and controls movement

FDA permits marketing of ClonoSEQ assay to detect minimal residual disease in blood cancer patients

Researchers deplete key protein for DNA replication using protein degradation system

Researchers design new combination therapy for reducing NSCLC cell growth

Engineering organoids from stem cells to model retina diseases

Australian scientists resolve a key question in ovarian cancer care

Study highlights role of non-mutational mechanism in myotonic dystrophy, other types of arrhythmias

Researchers start to understand how to make lab-grown heart cells mature

Research reveals how critical oocyte quality control process works

Researchers develop unique, biofuel-powered sensor to prevent and diagnose diseases

Genetic score helps predict future major coronary events, shows study

Food scientists can employ bacteriophage to destroy E. coli in drinking water

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging