Gene News and Research

Latest Gene News and Research

Alnylam announces positive results from Phase 1/2 study of lumasiran for treating primary hyperoxaluria-1

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today updated positive results from its Phase 1/2 clinical study of lumasiran, an investigational, subcutaneously administered RNAi therapeutic targeting glycolate oxidase for the treatment of primary hyperoxaluria type 1.

4 Oct 2018

Researchers decode regulatory impact on neuronal survival of small non-coding RNA molecule

An interdisciplinary and international research group led by Dr. Volker Busskamp from the Center for Regenerative Therapies Dresden at the TU Dresden has decoded the regulatory impact on neuronal survival of a small non-coding RNA molecule, so-called miRNA, at the highest resolution to date.

4 Oct 2018

Bradford and GE Healthcare collaborate to build new AI-powered hospital Command Center in Europe

Bradford Teaching Hospitals NHS Foundation Trust is collaborating with GE Healthcare to build a Command Center - like an air traffic control - at the Bradford Royal Infirmary, UK. A first of its kind in Europe, the Command Center will transform how care is delivered and organized as the number of patients at the hospital continues to increase.

4 Oct 2018

Working with Next Health World Innovation Forum to build a healthier future

The Innovation Forum is partnering with the Milner Therapeutics Institute in 2019 for the Next Health World Innovation Forum – a new international healthcare conference taking place from 26-27 June 2019, in Cambridge, UK.

4 Oct 2018

Ingenza announces extension of collaboration with Syngenta

Industrial biotech specialist Ingenza has announced that its collaboration with Syngenta for work on efficient technologies to support the development of crop protection products has been extended.

4 Oct 2018

Expert proposes new model to generate automated updates of genetic test results

Maybe the genetic test report your doctor ordered says your DNA contains many “variants of unknown significance.” Currently, up to 70 percent of such reports are negative or inconclusive.

4 Oct 2018

Genentech announces Phase III study results of baloxavir marboxil in people at high risk of flu

Genentech, a member of the Roche Group, today announced that the Phase III CAPSTONE-2 study showed treatment with baloxavir marboxil significantly reduced the time to improvement of influenza symptoms versus placebo in people at high risk of serious complications from the flu, which includes adults 65 years of age or older, or those who have conditions such as asthma, chronic lung disease, morbid obesity, or heart disease.

4 Oct 2018

Blocking stress-responsive protein reduces loss of tumor suppressor gene in breast cancer

Over half of all breast cancers carry genetic defects in the p53 gene, a powerful tumor suppressor. Loss of this gene increases the risk of getting breast cancer and the resultant cancers become highly resistant to treatment.

4 Oct 2018

New approach helps identify molecular alterations linked to prognosis, resistance of cancer

A new computational approach that allows the identification of molecular alterations associated with prognosis and resistance to therapy of different types of cancer was developed by the research group led by Nuno Barbosa Morais, Group Leader at Instituto de Medicina Molecular João Lobo Antunes, and now published open access in Nucleic Acids Research.

4 Oct 2018

Scientists discover key insights into how sperm and egg cells are formed

Key insights into how sperm and egg cells are formed have been discovered by scientists, shedding light on the earliest stages of their development.

4 Oct 2018

Study: Reducing mutated Huntington disease protein restores psychiatric impairments in mice

New research from the University of British Columbia suggests that reducing mutated Huntington disease protein in the brain can restore cognitive and psychiatric impairments in mice.

4 Oct 2018

Fruit fly protein shows protective effect on dopamine-producing neurons

Parkinson's disease is a neurodegenerative disorder that affects dopamine-producing or dopaminergic neurons. The progressive loss of these neurons is what leads to impairment in movement coordination in those suffering from the illness.

3 Oct 2018

Researchers create pseudo-embryos that mimic human embryos

Researchers have created murine pseudo-embryos that form the three major axes of the body and are able to accurately mimic human embryos.

3 Oct 2018

Genentech announces clinical data from studies investigating risdiplam in spinal muscular atrophy

Genentech, a member of the Roche Group, announced today interim clinical data from the dose-finding parts of the pivotal FIREFISH and SUNFISH studies investigating risdiplam in spinal muscular atrophy.

3 Oct 2018

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that it has submitted a Clinical Trial Authorization application to the Medicines and Healthcare products Regulatory Agency to initiate a Phase 1/2 study of ALN-AAT02, an investigational RNAi therapeutic targeting alpha-1 antitrypsin for the treatment of AAT deficiency-associated liver disease.

3 Oct 2018

Researchers insert just enough human DNA into mice to study preterm birth

Preterm birth remains a global epidemic linked to a lifetime of potential health complications. It also is difficult to study in living creatures--especially the uniquely precise biology of preterm birth in humans.

3 Oct 2018

Gene variant linked to Type 2 diabetes may predispose people to have lower body weight

A research team at the University of North Carolina at Chapel Hill's Gillings School of Global Public Health found that a well-known gene variant linked to Type 2 diabetes, called transcription Factor-7 like 2 gene, may also predispose someone to being leaner, or having a lower body weight.

3 Oct 2018

Gene News and Research

Latest Gene News and Research

Alnylam announces positive results from Phase 1/2 study of lumasiran for treating primary hyperoxaluria-1

Researchers decode regulatory impact on neuronal survival of small non-coding RNA molecule

Bradford and GE Healthcare collaborate to build new AI-powered hospital Command Center in Europe

Working with Next Health World Innovation Forum to build a healthier future

Ingenza announces extension of collaboration with Syngenta

Expert proposes new model to generate automated updates of genetic test results

Genentech announces Phase III study results of baloxavir marboxil in people at high risk of flu

Blocking stress-responsive protein reduces loss of tumor suppressor gene in breast cancer

New approach helps identify molecular alterations linked to prognosis, resistance of cancer

Scientists discover key insights into how sperm and egg cells are formed

Study: Reducing mutated Huntington disease protein restores psychiatric impairments in mice

Fruit fly protein shows protective effect on dopamine-producing neurons

Researchers create pseudo-embryos that mimic human embryos

Genentech announces clinical data from studies investigating risdiplam in spinal muscular atrophy

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Researchers insert just enough human DNA into mice to study preterm birth

Gene variant linked to Type 2 diabetes may predispose people to have lower body weight

Hopkins gastroenterologists use endoscopic procedure to deliver therapeutic genes to the liver

Aggressive breast cancer hijacks normal protective physiological process to survive

Study sheds light on transport of enzyme involved in stem cell differentiation to DNA

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging