contains the active ingredient cefepime hydrochloride
CONSUMER MEDICINE INFORMATION
What is in this leaflet
The medicine which your doctor has prescribed for you is called Cefepime Alphapharm.
The information in this leaflet answers some questions you may have about Cefepime
This leaflet does not contain all the information about Cefepime Alphapharm. Your
doctor or pharmacist has been provided with full information, and can answer any questions
you may have. Follow your doctor's advice, even if it differs from what is in this
You should read this leaflet carefully before Cefepime Alphapharm is given to you.
Keep this leaflet with your medicine. You may need to read it again
What CEFEPIME ALPHAPHARM is used for
Cefepime Alphapharm contains cefepime which belongs to a group of antibiotics called
cephalosporins. These antibiotics work by killing the bacteria that are causing the
Cefepime Alphapharm is an injectable antibiotic used for serious infections in adults
caused by bacteria in the lungs (pneumonia and bronchitis), in the kidney and bladder
(urinary tract infections), in the skin, inside the abdomen (peritonitis and biliary
tract infections), in the womb or vagina, or in the blood (septicaemia). It may be
given before surgery or if you have a lack of white blood cells with fever.
Cefepime Alphapharm is also used for serious infections in children over 2 months
of age caused by bacteria in the lungs (pneumonia), in the kidney and bladder (urinary
tract infections), or in the skin; or in the blood; or if the child has a lack of
white blood cells with fever.
There may be other reasons why your doctor has prescribed Cefepime Alphapharm. Ask
your doctor why Cefepime Alphapharm has been prescribed for you.
Before you take CEFEPIME ALPHAPHARM
When you must not take it
You should not be given Cefepime Alphapharm if:
you have an allergy to Cefepime Alphapharm, or to other cephalosporins or to any ingredient
listed at the end of this leaflet.
Some of the symptoms of an allergic reaction may include skin rash, difficulty breathing
you have had a serious reaction to penicillin.
Before you start to take it
Before you are given Cefepime Alphapharm your doctor must know:
if you have ever had any type of allergic reaction to penicillin medicines
if you have any allergies to other medicines or to any other substances such as foods,
preservatives or dyes
if you have ever had any other health problems or medical conditions such as:
severe bowel conditions or bowel disease
frequent infections such as fever, severe chills, sore throat or mouth ulcer or lack
of white blood cells.
a recent bone marrow transplant
cancer of the blood
low blood pressure
if you have ever suffered diarrhoea as a result of taking medicine
Pregnancy and breast-feeding
Tell your doctor if:
you are pregnant or intend to become pregnant
breast-feeding or plan to breast-feed
Like most medicines Cefepime Alphapharm is not recommended for women who are pregnant
or breast feeding.
However your doctor will discuss with you the possible risks and benefits of using
Cefepime Alphapharm during pregnancy.
Taking other medicines
Tell your doctor if you are taking any other medicines, including medicines that you
buy without a prescription from your pharmacy or health food shop. Some medicines
with Cefepime Alphapharm, these include:
any other antibiotic
fluid tablets (diuretics) such as Lasix, Midamor, or Moduretic.
These medicines may be affected by Cefepime Alphapharm, or may affect how well it
works. You may need different amounts of your medicine, or you may need to take different
Cefepime Alphapharm may be given to infants (over 2 months old) and children; Cefepime
Alphapharm is not recommended if the infant is less than 2 months old.
How to take Cefepime Alphapharm
Your doctor will decide what dose you will receive. The usual adult dose is 1 gram
given by injection every 12 hours (2 each day) for 7 to 10 days.
The dose of Cefepime Alphapharm for children aged 2 months to 12 years old will depend
on the weight of the child, the severity of the infection and the medical condition
of the child.
How it is given
Cefepime Alphapharm is given as a slow injection (or drip) directly into a vein or
as a deep injection into a large muscle.
The injection will be given to you by a nurse or doctor, you will not be giving the
injection to yourself.
Usually you will be in hospital when receiving Cefepime Alphapharm. Your doctor has
information on how to recognize and treat an overdose. Ask your doctor or nurse if
you have any concerns when you are receiving Cefepime Alphapharm.
While you are taking Cefepime Alphapharm
Things you must do
If the symptoms of your infection do not improve within a few days, or if they become
worse, you must tell your doctor.
If you get severe diarrhoea tell your doctor, pharmacist or nurse immediately even
if it occurs several weeks after Cefepime Alphapharm has been stopped.
Diarrhoea may mean that you have a serious condition affecting your bowel. You may
need urgent medical care. Do not take any diarrhoea medicine without checking with
your doctor first.
If you get a sore white mouth or tongue while receiving or soon after stopping Cefepime
Alphapharm, tell your doctor. Also tell your doctor if you get vaginal itching or
This may mean you have a fungal infection called thrush. Sometimes the use of Cefepime
Alphapharm allows fungi to grow and the symptoms described above to occur. Cefepime
Alphapharm does not work against fungi.
If you become pregnant while you are being given Cefepime Alphapharm tell your doctor.
If you are about to start taking any new medicine, tell your doctor and pharmacist
that you are receiving Cefepime Alphapharm.
If you have your urine tested for sugar while you are receiving Cefepime Alphapharm,
make sure your doctor knows which test is used. Cefepime Alphapharm may affect the
results of some of these tests.
Tell all the doctors, dentists and pharmacists who are treating you that you are receiving
Things to be careful of
Be careful driving or operating machinery until you know how Cefepime Alphapharm affects
you. Cefepime Alphapharm generally does not cause any problems with your ability to
drive a car or operate machinery. However as with other medicines, Cefepime Alphapharm
may cause dizziness, drowsiness or tiredness in some people.
It is important that you tell a nurse, doctor or pharmacist if you experience any
problems when you are being treated with Cefepime Alphapharm.
Cefepime Alphapharm helps most people with infections, but it may cause some unwanted
side effects in a few people. All medicines have side effects, some times they are
serious, most of the time they are not. You may need special medical treatment if
you get some of the side effects.
If there are any germs present which are not sensitive to Cefepime Alphapharm, they
may flourish during Cefepime Alphapharm therapy and cause other infections such as
Cefepime Alphapharm may cause adverse effects to the blood, liver or kidneys which
are detected by laboratory testing. It may be necessary to monitor these effects by
having your blood samples analysed regularly. Your doctor will advise if it is necessary
for you to have these tests done.
Call for a nurse or doctor if you experience any of the following:
Chest pain, increased heart beat, feeling faint, breathing difficulty, chills, dizziness,
feel confused, suffer hallucinations, twitching muscles or experience a seizure
Tell your doctor or pharmacist if you notice any of the following and they worry you:
oral thrush - white, furry, sore tongue and mouth
vaginal thrush - sore and itchy vagina and/or discharge
itching or burning while passing urine
cough, sore throat, mouth ulcers
swelling, pain and inflammation at the site of the injection
any change to your bowel habits - diarrhoea or constipation
pain in the gut, indigestion or upset stomach
skin rash or itchiness, skin redness
sweating, feeling unwell, fluid retention, headache, weakness, numbness
insomnia, anxiety, nervousness, confusion
After treatment with Cefepime Alphapharm is finished
Tell your doctor immediately if you notice any of the following side effects, particularly
if they occur several weeks after the treatment with Cefepime Alphapharm has stopped:
severe abdominal cramps or stomach cramps
watery and severe diarrhoea, which may also be bloody
fever with one or both of the above symptoms
These are rare but serious side effects. You may have a serious condition affecting
your bowel. Therefore you may need urgent medical attention. Although this side effect
is rare, do not take diarrhoea medicine without first checking with your doctor.
The list above is not a complete list of ALL possible side effects. Your doctor can
tell you more about the safety of Cefepime Alphapharm. Also, as with any medicine,
there are some side effects which are not yet known. Ask your doctor if you have any
After taking CEFEPIME ALPHAPHARM
Cefepime Alphapharm will be stored in the pharmacy or the Ward. The powder for injection
is usually kept in a cool dry place where the temperature stays below 25 degrees Celsius.
Protect from light.
What it looks like
CEFEPIME ALPHAPHARM is a white to pale yellow colour.
Active ingredient per vial:
CEFEPIME ALPHAPHARM 1g - contains cefepime (as hydrochloride) 1g
CEFEPIME ALPHAPHARM 2g - contains cefepime (as hydrochloride) 2g
The contents of each vial are dissolved in sterile water, 5% glucose or saline for
injections before the injection is given.
CEFEPIME ALPHAPHARM is supplied in Australia by:
Alphapharm Pty Limited
(ABN 93 002 359 739)
Level 1, 30 The Bond
30-34 Hickson Road
Millers Point NSW 2000
Phone: (02) 9298 3999
Australian Registration Numbers
CEFEPIME ALPHAPHARM 1g -
AUST R 161029
CEFEPIME ALPHAPHARM 2g -
AUST R 161030
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