Esophageal Cancer News and Research

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Esophageal Cancer is cancer that forms in tissues lining the esophagus (the muscular tube through which food passes from the throat to the stomach). Two types of esophageal cancer are squamous cell carcinoma (cancer that begins in flat cells lining the esophagus) and adenocarcinoma (cancer that begins in cells that make and release mucus and other fluids).

MACC1 gene can help predict better treatment options for patients with Klatskin carcinoma

Bile duct cancer is rare and is usually detected too late. Often only extensive liver surgery can help or, in rare cases, liver transplantation. But which patients will benefit from surgery and which will not, because their risk of cancer recurrence is too high? With the oncogene MACC1 as a biomarker, physicians for the first time have a tool to decide which treatment option is best for patients with Klatskin carcinoma, one type of bile duct cancer.

1 Sep 2015

LINE-1 jumping gene unusually active in gastrointestinal cancer

Results of a trio of studies done on human cancer tissue biopsies have added to growing evidence that a so-called jumping gene called LINE-1 is active during the development of many gastrointestinal cancers.

19 Aug 2015

Studies show jumping genes more active during development of gastrointestinal cancers

18 Aug 2015

Defects in mitochondria play key role in transition of normal cells to cancerous cells

Cancer cells defy the rules by which normal cells abide. They can divide without cease, invade distant tissues and consume glucose at abnormal rates.

9 Jul 2015

Portable microendoscope could eliminate need for costly biopsies for esophageal cancer patients

In a clinical study of patients in the United States and China, researchers found that a low-cost, portable, battery-powered microendoscope developed by Rice University bioengineers could eventually eliminate the need for costly biopsies for many patients undergoing standard endoscopic screening for esophageal cancer.

3 Jun 2015

Adaptimmune presents clinical results of NY-ESO TCR therapeutic candidate at ASCO 2015

Adaptimmune Therapeutics plc, a clinical stage biopharmaceutical company focused on the use of TCR engineered T-cell therapy to treat cancer, today announced a poster presentation of data on its lead clinical program, an affinity enhanced T-cell receptor (TCR) therapeutic targeting the NY-ESO-1 cancer antigen, in both solid and hematologic cancers.

2 Jun 2015

Game changing, breakthrough early cancer detection technology presented at ASCO 2015

Anpac Bio-Medical Science Co., Ltd., Chief Executive Officer and Scientist Dr. Chris Yu and the Anpac research team are introducing what the 2015 Nobel Prize Laureate Summit on Biomedical Science (NPLS) organizers published as, "game changing" and "breakthrough" early cancer detection technology research results at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago, Illinois, May 29 – June 2, 2015.

1 Jun 2015

Esophageal cancer patients treated with proton therapy experience less toxic side effects

New research by scientists at the University of Maryland School of Medicine has found that esophageal cancer patients treated with proton therapy experienced significantly less toxic side effects than patients treated with older radiation therapies.

24 May 2015

Multi-center study shows WATS3D biopsy increases detection of esophageal pre-cancer by 60% following endoscopic ablation of Barrett’s Esophagus

CDx Diagnostics announced today new clinical data from a multi-center study demonstrating the utility of the WATS3D biopsy for post-ablation surveillance of Barrett’s esophagus and esophageal dysplasia...

18 May 2015

Multi-center study shows WATS3D biopsy increases detection of esophageal pre-cancer by 60% following endoscopic ablation of Barrett’s Esophagus

18 May 2015

Studies support use of ThyraMIR and ThyGenX to improve detection of benign/malignant thyroid nodules

Data will be presented at both Digestive Disease Week (DDW) and the American Association of Clinical Endocrinologists (AACE) annual medical meetings.

18 May 2015

Mount Sinai researchers present landmark studies at AATS meeting

Icahn School of Medicine at Mount Sinai researchers presented several landmark studies at the 2015 American Association for Thoracic Surgery meeting in Seattle.

5 May 2015

Long-term survivors of esophageal cancer still face continued risks, study finds

Patients with esophageal cancer who survive 5 years after undergoing surgery might breathe a sigh of relief and become complacent about continued monitoring. In fact, there is little published information on the outcome of patients with locally advanced esophageal cancer (LAEC) who survive beyond the 5-year mark.

30 Apr 2015

Incidence of esophageal cancer linked to GERD rises six-fold in recent decades

Esophageal cancer is one of the fastest-growing and deadliest cancers in the U.S. According to the American Cancer Society, an estimated 17,000 new cases of esophageal cancer will be diagnosed in 2015. Incidence of adenocarcinoma, a type of esophageal cancer linked to GERD (gastroesophageal reflux disease) has risen six-fold in recent decades.

21 Apr 2015

St. John Hospital first in Michigan to offer new alternative treatment for acid reflux disease

St. John Hospital is among the first in the state and the only site in southeast Michigan to offer a new alternative treatment for patients with acid reflux disease.

10 Feb 2015

Clinical study data of Advaxis' Lm-LLO immunotherapies to be presented at SITC Annual Meeting

Advaxis, Inc., a cancer immunotherapy company, today announced the abstracts of three preclinical and clinical studies highlighting the survival outcomes and anti-tumor effects of its proprietary Lm-LLO cancer immunotherapy technology at the Society for Immunotherapy of Cancer (SITC) 29th Annual Meeting, November 6-9, 2014 at the Gaylord National Hotel and Convention Center in National Harbor, Maryland.

5 Nov 2014

STS releases new clinical practice guidelines for treating esophageal cancer

The Society of Thoracic Surgeons has released new clinical practice guidelines for treating cancer of the esophagus and gastroesophageal junction (area where the esophagus meets the stomach).

30 Oct 2014

Esophageal tissue can be grown in vivo from human and mouse cells, say researchers

In a first step toward future human therapies, researchers at The Saban Research Institute of Children's Hospital Los Angeles have shown that esophageal tissue can be grown in vivo from both human and mouse cells. The study has been published online in the journal Tissue Engineering, Part A.

20 Oct 2014

Research findings could provide new insights into esophageal cancer, Barrett's esophagus

Despite previous indications to the contrary, the esophagus does have its own pool of stem cells, said researchers from the University of Pittsburgh School of Medicine in an animal study published online today in Cell Reports.

20 Oct 2014

Pinnacle initiates pivotal Phase 3 trial in Germany for rare form of bile duct cancer

Pinnacle Biologics, Inc., a subsidiary of Concordia Healthcare Corp., announced today the initiation of the pivotal Phase 3 trial (OPUS) in Germany for a rare form of bile duct cancer for which there is currently no acceptable therapy.

7 Oct 2014

Esophageal Cancer News and Research

Further Reading

MACC1 gene can help predict better treatment options for patients with Klatskin carcinoma

LINE-1 jumping gene unusually active in gastrointestinal cancer

Studies show jumping genes more active during development of gastrointestinal cancers

Defects in mitochondria play key role in transition of normal cells to cancerous cells

Portable microendoscope could eliminate need for costly biopsies for esophageal cancer patients

Adaptimmune presents clinical results of NY-ESO TCR therapeutic candidate at ASCO 2015

Game changing, breakthrough early cancer detection technology presented at ASCO 2015

Esophageal cancer patients treated with proton therapy experience less toxic side effects

Multi-center study shows WATS3D biopsy increases detection of esophageal pre-cancer by 60% following endoscopic ablation of Barrett’s Esophagus

Multi-center study shows WATS3D biopsy increases detection of esophageal pre-cancer by 60% following endoscopic ablation of Barrett’s Esophagus

Studies support use of ThyraMIR and ThyGenX to improve detection of benign/malignant thyroid nodules

Mount Sinai researchers present landmark studies at AATS meeting

Long-term survivors of esophageal cancer still face continued risks, study finds

Incidence of esophageal cancer linked to GERD rises six-fold in recent decades

St. John Hospital first in Michigan to offer new alternative treatment for acid reflux disease

Clinical study data of Advaxis' Lm-LLO immunotherapies to be presented at SITC Annual Meeting

STS releases new clinical practice guidelines for treating esophageal cancer

Esophageal tissue can be grown in vivo from human and mouse cells, say researchers

Research findings could provide new insights into esophageal cancer, Barrett's esophagus

Pinnacle initiates pivotal Phase 3 trial in Germany for rare form of bile duct cancer

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