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OCuSOFT, Ardeo partner to distribute novel dry eye therapy in the U.S. and Canada

OCuSOFT, Inc., an ophthalmic pharmaceutical research, development and supply company today announced an exclusive multiyear agreement with Ardeo Health, LLC to distribute a novel dry eye therapy under license from Novagali Pharma S.A. of Evry, France, Nova23041.

15 Jun 2011

Study links cysteine with obesity-related diseases

People with high levels of the amino acid cysteine carry 6-10 kilograms more fat than other people. Norwegian researchers studying this phenomenon are generating knowledge which could help to prevent and treat life-threatening obesity.

15 Jun 2011

Calcium-sensing receptor plays key role in lethal lung cancer complication

A protein previously thought not to exist in adult human lungs not only is present in normal and cancerous lung tissue, scientists have found, but it also has a major role in the development of a lethal complication of some lung cancers.

14 Jun 2011

Mother to donate her womb to daughter

A 56-year-old mother hopes to become the first woman to have her womb transplanted into her daughter. Eva Ottoson who lives in Nottinghamshire has agreed to take part in the medical procedure that would see her donate her uterus to her daughter.

13 Jun 2011

Severe sleep apnea increases risk of gestational diabetes and preterm birth in pregnant women

Sleep apnea is associated with an increased risk of adverse pregnancy outcomes, suggests a research abstract that will be presented Monday, June 13, in Minneapolis, Minn., at SLEEP 2011, the 25th Anniversary Meeting of the Associated Professional Sleep Societies LLC (APSS).

13 Jun 2011

New drug more effective than standard treatment to prevent heart-attack deaths

Robert Storey, Professor of Cardiology at the University of Sheffield's Department of Cardiovascular Science, presented findings today that confirm one in five deaths in the year following a heart attack could be prevented if a new drug, ticagrelor, was used instead of the standard treatment, clopidogrel.

13 Jun 2011

Final data from Alexion's Soliris Phase 2 studies on aHUS presented at EHA 2011

Alexion Pharmaceuticals, Inc. today announced the presentation of final data from the two Phase 2 studies of Soliris as a treatment for patients with atypical hemolytic uremic syndrome.

13 Jun 2011

Protein missing in fragile X syndrome acts as a molecular toggle switch in brain cells

New research shows how the protein missing in fragile X syndrome - the most common inherited form of intellectual disability - acts as a molecular toggle switch in brain cells.

10 Jun 2011

Adaptation of fat cell membranes to obesity may play a key role in early stages of inflammatory disorders

The mechanisms by which obesity leads towards metabolic co-morbidities, such as diabetes mellitus, are poorly understood and of great public health interest. A study led by Matej Orešič from VTT Technical Research Centre of Finland suggests that adaptation of fat cell membranes to obesity may play a key role in the early stages of inflammatory disorders.

10 Jun 2011

Blinatumomab phase 2 trial results on acute lymphoblastic leukemia to be presented at EHA 2011

Data to be presented tomorrow at the 16th Annual Meeting of the European Hematology Association (EHA) in London, UK, show that Micromet's blinatumomab produced a high complete remission rate in adult patients with acute lymphoblastic leukemia (ALL) who had relapsed following treatment with standard therapy.

10 Jun 2011

German hospital adopts Luminex new diagnostic assay to manage current E.coli outbreak

Luminex Corporation and the Kliniken der Stadt Koln, Institute of Pathology and Institute for Hygiene today announced that Luminex's newly released xTAG Gastrointestinal Pathogen Panel (GPP) is being used successfully as a first-line screen for patients at Kliniken der Stadt Koln suspected of having an E. coli infection.

From Luminex 10 Jun 2011

Dairy Council of California co-hosts June 12 symposium at IFT's food expo

From body builders to baby boomers, more Americans are consuming higher-protein diets for benefits including muscle building and maintenance in later life, satiety, weight loss and more.

10 Jun 2011

Pall's GeneDisc System helps German authorities screen for deadly E.coli strain

Pall Corporation's GeneDisc System is helping German authorities screen for a deadly strain of E.coli that has sickened nearly 3000 people and disrupted that nation's food industry. Pall's GeneDisc technology is being used by Germany's national reference laboratory to expedite testing of food samples for the toxic strain of the pathogen known as E.coli O104:H4.

From Pall Corporation 10 Jun 2011

Toxin known to affect humans identified in endangered Hawaiian monk seal

Researchers from NOAA have discovered a potent and highly-debilitating toxin in the endangered Hawaiian monk seal, a first-of-its-kind chemical finding that is now prompting investigations of other marine mammals in the state.

9 Jun 2011

Hepatitis C virus (HCV)-associated liver disease after liver transplantation

Hepatitis C virus (HCV)-associated liver disease continues to be the most common indication for liver transplantation (LT) in the United States accounting for nearly 50% of all liver transplants. Recurrence is universal in patients viremic at the time of transplantation with histological hepatitis developing in the majority of patients. Although the natural history of recurrent HCV is difficult to predict, it is widely accepted that cirrhosis from recurrent HCV occurs in up to 30% of patients within five years of transplantation.

8 Jun 2011

Health officials rule out sprouts as source of German E. coli outbreak

Health officials in Germany are continuing to search for the source of an E. coli outbreak after tests on suspected sprouts from a farm in the north of the country came back negative, Deutsche Welle reports. The outbreak has killed 22 people and sickened more than 2,000 (Hallam/Penfold, 6/6).

8 Jun 2011

$Telik initiates Telintra Phase 2 trial in Revlimid refractory or resistant, del 5q MDS$

Telik initiates Telintra Phase 2 trial in Revlimid refractory or resistant, del 5q MDS

Telik, Inc. today announced the initiation of a Phase 2 clinical trial to evaluate oral Telintra in patients with Revlimid refractory or resistant, deletion 5q myelodysplastic syndrome.

8 Jun 2011

Positive results from Celator CPX-351 Phase 2b study on acute myeloid leukemia presented at ASCO

Celator Pharmaceuticals today announced positive clinical results in elderly patients with newly-diagnosed secondary acute myeloid leukemia (sAML) treated with CPX-351 Liposome Injection.

7 Jun 2011

Gleevec shows significant overall survival benefit for patients w/ GIST after 3 years of adjuvant treatment vs. 1 year

Novartis announced new data today showing a significant improvement in both recurrence-free survival and overall survival for patients taking Gleevec® (imatinib mesylate)* tablets for three years after surgery to remove KIT (CD117)-positive gastrointestinal stromal tumors (KIT+ GIST) compared to one year of treatment. These data will be presented at the 47th American Society of Clinical Oncology (ASCO) plenary session on Sunday, June 5.

6 Jun 2011

Onconova to initiate ESTYBON Phase II/III study in pancreatic cancer

Onconova Therapeutics, Inc. announced two advances in the clinical development of ESTYBON (rigosertib, ON 01910.Na) in presentations at the annual meeting of the American Society of Clinical Oncology (ASCO), June 3-7, 2011, in Chicago, Illinois.

6 Jun 2011

Syndrome News and Research

OCuSOFT, Ardeo partner to distribute novel dry eye therapy in the U.S. and Canada

Study links cysteine with obesity-related diseases

Calcium-sensing receptor plays key role in lethal lung cancer complication

Mother to donate her womb to daughter

Severe sleep apnea increases risk of gestational diabetes and preterm birth in pregnant women

New drug more effective than standard treatment to prevent heart-attack deaths

Final data from Alexion's Soliris Phase 2 studies on aHUS presented at EHA 2011

Protein missing in fragile X syndrome acts as a molecular toggle switch in brain cells

Adaptation of fat cell membranes to obesity may play a key role in early stages of inflammatory disorders

Blinatumomab phase 2 trial results on acute lymphoblastic leukemia to be presented at EHA 2011

German hospital adopts Luminex new diagnostic assay to manage current E.coli outbreak

Dairy Council of California co-hosts June 12 symposium at IFT's food expo

Pall's GeneDisc System helps German authorities screen for deadly E.coli strain

Toxin known to affect humans identified in endangered Hawaiian monk seal

Hepatitis C virus (HCV)-associated liver disease after liver transplantation

Health officials rule out sprouts as source of German E. coli outbreak

Telik initiates Telintra Phase 2 trial in Revlimid refractory or resistant, del 5q MDS

Positive results from Celator CPX-351 Phase 2b study on acute myeloid leukemia presented at ASCO

Gleevec shows significant overall survival benefit for patients w/ GIST after 3 years of adjuvant treatment vs. 1 year

Onconova to initiate ESTYBON Phase II/III study in pancreatic cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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