Syndrome News and Research

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New understanding of how host and foreign structures are distinguished by front-line defence mechanism

This week, the highly-respected US Academy of Sciences journal (PNAS) published an article describing how the first line of defence of the human immune system distinguishes between microbes and the body's own structures.

5 Feb 2011

Patients receiving cancer treatment may experience skin, hair, nail problems

A cancer diagnosis and subsequent treatment, which commonly includes chemotherapy or radiation, can be taxing physically and emotionally on any patient. If that is not enough, dermatologists are cautioning patients receiving cancer treatment and cancer survivors that they may experience a host of skin, hair or nail problems as a direct result of their therapy that may require additional treatment by a dermatologist.

5 Feb 2011

Canisius College professor explains long-term benefits of leisure

According to leisure expert Dr. E. Christine Moll, "play" is as important to a person's health as keeping cholesterol levels in check and getting regular exercise. Moll, a professional counselor and professor of counseling and human services at Canisius College in Buffalo, NY, explains that leisure is like medicine.

5 Feb 2011

Scientists discover how stressed cells boost thrombin production

In our not-so-distant evolutionary past, stress often meant imminent danger, and the risk of blood loss, so part of our body's stress response is to stock-pile blood-clotting factors. Scientists in the Molecular Medicine Partnership Unit, a collaboration between the European Molecular Biology Laboratory in Heidelberg, Germany, and the University of Heidelberg Medical Centre, have discovered how stressed cells boost the production of the key blood-clotting factor, thrombin.

4 Feb 2011

Scientists discover how stressed cells boost production of key blood-clotting factor, thrombin

Scientists in a collaboration between EMBL Heidelberg and the University of Heidelberg Medical Centre have discovered how stressed cells boost the production of the key blood-clotting factor, thrombin. Their work, published today in Molecular Cell, shows how cancer cells may be taking advantage of this process, and opens new possibilities for fighting back against cancer and septicaemia.

4 Feb 2011

How body's first line of defence distinguishes between microbes and own structures

4 Feb 2011

NeuroMetrix fourth quarter total revenues decrease to $3.1 million

NeuroMetrix, Inc., a science-based health care company transforming patient care through neurotechnology, today reported business and financial highlights for the quarter and year ended December 31, 2010.

3 Feb 2011

Losartan improves effectiveness of nanotherapeutics against cancer

Low doses of an inexpensive, FDA-approved hypertension medication may improve the results of nanotherapeutic approaches to cancer treatment. In a report in the early edition of Proceedings of the National Academy of Sciences, Massachusetts General Hospital (MGH) investigators describe experiments showing that the generic drug losartan, by modifying the network of collagen fibers that characterizes most solid tumors, improved the effectiveness of two nanotherapeutics against several types of cancer.

3 Feb 2011

Study reveals how MMSET gene enables disease-causing mutations to occur

For several decades, researchers have been linking genetic mutations to diseases ranging from cancer to developmental abnormalities. What hasn't been clear, however, is how the body's genome sustains such destructive glitches in the first place.

3 Feb 2011

Ritalin may help improve brain function in children with iron deficiency

Ritalin may help improve brain function in adolescent rats that were iron deficient during infancy, according to a team of Penn State neuroscientists. This may have implications for iron-deficient human infants as well.

3 Feb 2011

Older people with metabolic syndrome may face high risk of developing memory loss

Older people with larger waistlines, high blood pressure and other risk factors that make up metabolic syndrome may be at a higher risk for memory loss, according to a study published in the February 2, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

3 Feb 2011

Study: Simple sideline test can accurately detect concussions in athletes

A simple test performed at the sideline of sporting events can accurately detect concussions in athletes, according to study by researchers at the University of Pennsylvania School of Medicine. Current sideline tests can leave a wide amount a brain function untested following concussion.

2 Feb 2011

Study identifies effects of multiple previous concussions on high school students

A previous study of ex-NFL players showed that the damage caused by concussions occurs in the same region of the brain as damage caused by Alzheimer's disease, resulting in increased concern over post-concussion related injuries and trauma of athletes. Philip Schatz Ph.D., professor of psychology, and his associates recently published a study in Neurosurgery that identifies potentially enduring effects of multiple previous concussions on high school students.

2 Feb 2011

Nitrate boosts efficiency of mitochondria

The spinach-eating cartoon character Popeye has much to teach us, new research from the Swedish medical university Karolinska Institutet shows. The muscles' cellular power plants - the mitochondria - are boosted by nitrate, a substance found in abundance in vegetables such as lettuce, spinach and beetroot.

2 Feb 2011

BioMarin commences GALNS Phase 3 trial in patients with Morquio A Syndrome

BioMarin Pharmaceutical announced today that it has initiated a pivotal Phase 3 trial for N-acetylgalactosamine 6-sulfatase, intended for the treatment of the lysosomal storage disorder Mucopolysaccharidosis Type IVA, also called Morquio A Syndrome.

1 Feb 2011

Discovery Labs provides expanded update on efforts to gain FDA marketing authorization for Surfaxin in RDS

Discovery Laboratories, Inc. is providing an expanded update regarding ongoing efforts to file a Complete Response intended to gain U.S. Food and Drug Administration (FDA) marketing authorization for Surfaxin® for the prevention of respiratory distress syndrome (RDS) in premature infants.

1 Feb 2011

Study establishes direct link between morphine abstinence and depressive-like symptoms

Opiate abuse is a chronic disorder and maintaining abstinence represents a major challenge for addicts.

1 Feb 2011

PhRMA: 299 medicines under development for prevention and treatment of heart disease and stroke

An American dies of heart disease every 39 seconds, and African Americans suffer a higher death rate from heart disease and stroke than Americans overall. Partly as a result of having the highest prevalence of high blood pressure in the world, African Americans have a 1.5 times greater rate of heart disease death than other Americans and a 1.8 times greater rate of fatal stroke.

1 Feb 2011

New study sheds further light on stroke recovery process

Most people who survive a stroke recover some degree of their motor, sensory and cognitive functions over the following months and years. This recovery is commonly believed to reflect a reorganisation of the central nervous system that occurs after brain damage. Now a new study, published in the February 2011 issue of Elsevier's Cortex, sheds further light on the recovery process through its effect on language skills.

1 Feb 2011

French guy says Parkinson’s drug induced gambling and gay sex addiction, tries to sue GSK for $610,000

GlaxoSmithKline is being sued this week by a French father-of-two, alleging the British pharmaceutical firm’s drug – Reqip (Ropirnirole) to treat Parkinson’s disease turned him into a gay sex and gambling addict. Parkinson’s disease is a seriously and progressively debilitating disease that leads to tremors, slowing of movements and ultimately total immobility.

1 Feb 2011

Syndrome News and Research

New understanding of how host and foreign structures are distinguished by front-line defence mechanism

Patients receiving cancer treatment may experience skin, hair, nail problems

Canisius College professor explains long-term benefits of leisure

Scientists discover how stressed cells boost thrombin production

Scientists discover how stressed cells boost production of key blood-clotting factor, thrombin

How body's first line of defence distinguishes between microbes and own structures

NeuroMetrix fourth quarter total revenues decrease to $3.1 million

Losartan improves effectiveness of nanotherapeutics against cancer

Study reveals how MMSET gene enables disease-causing mutations to occur

Ritalin may help improve brain function in children with iron deficiency

Older people with metabolic syndrome may face high risk of developing memory loss

Study: Simple sideline test can accurately detect concussions in athletes

Study identifies effects of multiple previous concussions on high school students

Nitrate boosts efficiency of mitochondria

BioMarin commences GALNS Phase 3 trial in patients with Morquio A Syndrome

Discovery Labs provides expanded update on efforts to gain FDA marketing authorization for Surfaxin in RDS

Study establishes direct link between morphine abstinence and depressive-like symptoms

PhRMA: 299 medicines under development for prevention and treatment of heart disease and stroke

New study sheds further light on stroke recovery process

French guy says Parkinson’s drug induced gambling and gay sex addiction, tries to sue GSK for $610,000

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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