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Stemline to feature SL-401 clinical efficacy at ASH Annual Meeting

Stemline Therapeutics, Inc. today announced that two abstracts featuring SL-401 clinical efficacy in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), and pre-clinical activity in chronic myeloid leukemia (CML) have been selected for presentation at the upcoming 52nd Annual Meeting of the American Society of Hematology (ASH) to be held in Orlando, FL from December 4-7, 2010.

2 Dec 2010

Researchers identify blip in gene that causes JMP syndrome

UT Southwestern Medical Center researchers have identified a gene responsible for a rare disease that results in severe joint stiffness, muscle loss, anemia and panniculitis-induced lipodystrophy, or JMP syndrome.

2 Dec 2010

U.N. says PMTCT of HIV is achievable; efforts must target millions currently 'falling through the cracks'

A generation of babies could be born free of AIDS if the international community stepped up efforts to provide universal access to HIV prevention, treatment and social protection, the United Nations said on Tuesday, Reuters reports.

2 Dec 2010

Research could lead to new drug treatment for metabolic diseases

A team of Harvard School of Public Health (HSPH) scientists report finding a molecular "switch" that can "turn off" some cellular processes that are protective against aging and metabolic diseases. While more research is needed, the findings may open doors for new drug treatments to halt or slow development of metabolic diseases like type 2 diabetes or heart disease. The research findings appear in the December 1, 2010 issue of Cell Metabolism.

1 Dec 2010

Vitamin D supplementation may reduce risk of diabetes, heart disease: Research

Researchers from the UC Davis Health System have found that compared with healthy controls, blood levels of vitamin D are significantly reduced in patients in the Sacramento area with metabolic syndrome, a constellation of disease risk factors that affects about one in three U.S. adults and predisposes them to diabetes, heart disease and stroke.

1 Dec 2010

Common sleep complaints predict development of metabolic syndrome: Study

A study in the Dec. 1 issue of the journal SLEEP found that loud snoring and two common insomnia symptoms difficulty falling asleep and unrefreshing sleep each significantly predicted the development of the metabolic syndrome. The study emphasizes the importance of screening for common sleep complaints in routine clinical practice.

1 Dec 2010

Mitochondrial dysfunction observed in children with full syndrome autism

Preliminary research has found that children with autism are more likely to have impaired mitochondrial function (structures within cells responsible for energy production) and mitochondrial DNA abnormalities than typically developing children, according to a study in the December 1 issue of JAMA.

1 Dec 2010

Ikaria initiates enrollment in LUCASSIN Phase III trial for HRS Type 1

Ikaria, Inc. announced that it has enrolled the first patients in its pivotal Phase III trial for LUCASSIN® (terlipressin). The multi-center, randomized, placebo-controlled, double-blind trial is known as the REVERSE Trial.

30 Nov 2010

Cyrenaic announces results of CYR-101 Phase IIa clinical trial for schizophrenia

Cyrenaic Pharmaceuticals Inc. a private drug development company focused on the treatment of CNS disorders, today announced Phase IIa clinical results for CYR-101, its novel investigational drug for the treatment of schizophrenia. The results from the study showed that the drug alleviated the symptoms of the disease, including the negative and cognitive symptoms.

30 Nov 2010

Genetic screening for Lynch syndrome as cost-effective as other cancer screening procedures

Myriad Genetics, Inc. today said results from a major health economics study in Cancer Prevention Research, a journal of the American Association for Cancer Research (AACR), found that screening for inherited gene mutations in the genes that cause a major colorectal cancer syndrome called Lynch Syndrome, is both medically and cost effective.

30 Nov 2010

New review from JASN highlights hazards of fructose

More and more people have become aware of the dangers of excessive fructose in diet. A new review on fructose in an upcoming issue of the Journal of the American Society of Nephrology (JASN) indicates just how dangerous this simple sugar may be.

30 Nov 2010

Nine out of ten of all primary care centers in Sweden prescribe physical activity

Prescribing physical activity for the purpose of preventing and treating various conditions can now become a reality for healthcare professionals all over the world.

30 Nov 2010

New findings could drive medical advances in genetic disorders that cause infertility

A hormone responsible for the onset of puberty can end up stuck in the wrong part of the body if the nerve pathways responsible for its transport to the brain fail to develop properly, according to research funded by the Biotechnology and Biological Sciences Research Council (BBSRC).

30 Nov 2010

RCSI researchers discover potential new target for diarrhoea associated intestinal diseases

A study by researchers in the Royal College of Surgeons in Ireland (RCSI) has uncovered a potential new target for the treatment of a range of intestinal diseases that are associated with diarrhoea. Current medications are often ineffective and can have serious side effects so this discovery gives hope for the development of new treatments for sufferers of intestinal disease.

30 Nov 2010

3SBio acquires pegsiticase global rights from EnzymeRx for $6.25 million

3SBio Inc., a leading China-based biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products, announced that is has acquired worldwide rights of pegsiticase for all indications from EnzymeRx for a total consideration of US$6.25 million.

29 Nov 2010

Superantigens can disrupt immune system, can cause more illnesses

Superantigens, the toxins produced by staphylococcus bacteria, are more complex than previously believed, reveals a team of researchers from the University of Gothenburg in an article published today in the scientific journal Nature Communications. Their discovery shows that the body's immune system can cause more illnesses than realised.

29 Nov 2010

Study indicates high self-rated lifetime prevalence of depression among psychiatrists

This study addresses depression and burn-out among a sample of psychiatrists collected at a professional congress. Within several constraints, the results indicate an high self-rated lifetime prevalence of depression of 41.6% among the sample. Also noteworthy is that a fifth (20.3%) of the sample showed evidence of acute depressive symptoms.

26 Nov 2010

Doctors treating female epilepsy patients have to consider specific hormonal situation

Doctors treating female epilepsy patients have to take account of the specific hormonal situation in women. Such an approach can often reduce the limitations imposed by the disease. This is the conclusion reached by Sabine Weil of Munich University and her co-authors in the latest issue of Deutsches Ärzteblatt International

25 Nov 2010

Immunity-enhancing probiotics may be the best line of defense for good health

Good bacteria, bad bacteria, billions of bacteria—sounds downright germy. But the truth is that research in gut health is germinating more insight into the role bacteria, also known as "probiotics," play in our overall health and wellness.

25 Nov 2010

Collective efforts in transplantation reduces risk of treatment-related complications in blood cancer

A decade of refinements in marrow and stem cell transplantation to treat blood cancers significantly reduced the risk of treatment-related complications and death, according to an institutional self-analysis of transplant-patient outcomes conducted at Fred Hutchinson Cancer Research Center.

25 Nov 2010

Syndrome News and Research

Stemline to feature SL-401 clinical efficacy at ASH Annual Meeting

Researchers identify blip in gene that causes JMP syndrome

U.N. says PMTCT of HIV is achievable; efforts must target millions currently 'falling through the cracks'

Research could lead to new drug treatment for metabolic diseases

Vitamin D supplementation may reduce risk of diabetes, heart disease: Research

Common sleep complaints predict development of metabolic syndrome: Study

Mitochondrial dysfunction observed in children with full syndrome autism

Ikaria initiates enrollment in LUCASSIN Phase III trial for HRS Type 1

Cyrenaic announces results of CYR-101 Phase IIa clinical trial for schizophrenia

Genetic screening for Lynch syndrome as cost-effective as other cancer screening procedures

New review from JASN highlights hazards of fructose

Nine out of ten of all primary care centers in Sweden prescribe physical activity

New findings could drive medical advances in genetic disorders that cause infertility

RCSI researchers discover potential new target for diarrhoea associated intestinal diseases

3SBio acquires pegsiticase global rights from EnzymeRx for $6.25 million

Superantigens can disrupt immune system, can cause more illnesses

Study indicates high self-rated lifetime prevalence of depression among psychiatrists

Doctors treating female epilepsy patients have to consider specific hormonal situation

Immunity-enhancing probiotics may be the best line of defense for good health

Collective efforts in transplantation reduces risk of treatment-related complications in blood cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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