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Scientists discover simple molecular test to block GOAT enzyme

Scientists at The Scripps Research Institute have designed a new molecular test that will allow researchers to look for potential drugs targeting a human metabolic enzyme believed to stimulate the appetite and play a role in diabetes.

17 Sep 2010

Metabolism imbalance increases asthma risk in children: Research

Even children of a healthy weight who have an imbalanced metabolism due to poor diet or exercise may be at increased risk of asthma, according to new research, which challenges the widespread assumption that obesity itself is a risk factor for asthma.

17 Sep 2010

ISTA Pharmaceuticals initiates REMURA Phase 3 clinical program for dry eye disease

ISTA Pharmaceuticals, Inc., today announced that it has initiated a Phase 3 clinical program of ISTA's proprietary formulation of REMURA (bromfenac ophthalmic solution for dry eye) for alleviating the signs and symptoms of dry eye disease. The Phase 3 efficacy studies are being conducted under a Special Protocol Assessment (SPA) agreed upon with the U.S. Food and Drug Administration (FDA).

16 Sep 2010

Intensive care diary entries can reduce PTSD rates: Study

Some intensive care patients develop post-traumatic stress syndrome (PTSD) after the trauma of a difficult hospital stay, and this is thought to be exacerbated by delusional or fragmentary memories of their time in the intensive care unit. Now researchers writing in BioMed Central's open access journal Critical Care have found that if staff and close relatives make a diary for patients, featuring information about their stay and accompanied by photographs, PTSD rates can be significantly reduced.

16 Sep 2010

Hormone Foundation produces two fact sheets to dispel myths of adrenal fatigue, Wilson's temperature syndrome

The Hormone Foundation, the public education affiliate of The Endocrine Society, has produced two new fact sheets to dispel myths about so-called "diseases" popularized through the Internet: adrenal fatigue and Wilson's temperature syndrome.

16 Sep 2010

Endoscopic laser spine procedures replace traditional open back surgery

The Bonati Spine Institute, the leading center for the patented Bonati Spine Procedures for minimally invasive laser spine surgery, supports recent studies by highly respected organizations such as the Journal of the America Board of Family Medicine and Consumer Reports reporting an unnecessary growth in tests and treatments targeting back pain.

16 Sep 2010

Anonymous Funding promotes drug development for Fragile X syndrome treatment

Funding from an anonymous wealthy family has been the secret to progress, at long last, in developing drugs that show promise for helping millions of people worldwide with Fragile X syndrome, the most common genetic cause of autism. That's the topic of a fascinating article in the current issue of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine.

16 Sep 2010

Abbott issues statement in response to FDA's mixed vote for weight loss medication sibutramine

The U.S. Food and Drug Administration today held an Endocrinologic and Metabolic Drugs Advisory Committee to review the results of SCOUT and the weight loss medication sibutramine (sold as Meridia® in the United States).

16 Sep 2010

Physically active adolescents with fibromyalgia report lower levels of pain, disability: Study

Adolescents with fibromyalgia who are physically active report lower levels of pain and disability, according to findings of a multicenter study published in The Journal of Pain, published by the American Pain Society, ampainsoc.org.

16 Sep 2010

Gene network behind hardening of arteries, coronary heart disease identified

A gene network behind hardening of the arteries and coronary heart disease has been identified by a team of scientists from Australia, Europe and the United Kingdom. Their findings expose potential targets for the treatment of heart disease.

16 Sep 2010

FDA updates dosing recommendation for Valcyte medication

The U.S. Food and Drug Administration is notifying health care professionals of updated dosing recommendations for Valcyte (valganciclovir) oral tablets and solution used by children and adolescents receiving a kidney or heart transplant.

16 Sep 2010

UK HealthCare announces successful kidney transplant surgery in 16-year-old

UK HealthCare announces the revitalization of its pediatric kidney transplant program with the successful transplant surgery of 16-year-old Courtney Stroud, of Carlisle, Ky. Courtney's transplant was performed Aug. 31 at Kentucky Children's Hospital.

15 Sep 2010

Danny Davis to discuss diabetes, obesity rates in U.S. at UIC Midwest Conference

U.S. Rep. Danny Davis (D-Chicago) will give opening remarks when the Institute of Medicine of the National Academies convenes a regional meeting Sept. 21 at the University of Illinois at Chicago to discuss the rapidly rising rates of diabetes and obesity in the U.S.

15 Sep 2010

NBCA arms healthcare professionals to 'Stop the Clot'

The National Blood Clot Alliance (NBCA) is making available an easily accessible, no-cost online curriculum for nurses, nurse practitioners, physician assistants, and pharmacists to help increase understanding about the diagnosis and treatment of blood clots and blood clotting disorders.

15 Sep 2010

AMRI selects compound for advanced preclinical testing in treatment of IBS

AMRI today announced the selection of a compound from its proprietary research program for the treatment of irritable bowel syndrome (IBS) for advanced preclinical testing, with the goal of submitting an Investigational New Drug Application (IND) with the U.S. Food and Drug Administration (FDA) in 2011.

15 Sep 2010

Mechanism behind gene mutation leading to development of cleft palate

Researchers from Mount Sinai School of Medicine have found a new mechanism that explains why a certain gene mutation causes craniofrontonasal syndrome (CFNS), a disorder that causes cleft palate and other malformations in the face, brain, and skeleton. Cleft palate affects one of every 1,000 newborns. The research is published in the September 15 issue of Genes & Development.

15 Sep 2010

Hormone melatonin improves egg quality in IVF

Poor egg (oocyte) quality is an important cause of female infertility. Low quality eggs may have several problems, for example they may not divide properly, or they may be missing certain chromosomes. Egg quality also declines with age, and certain medical conditions, such as PolyCystic Ovary Syndrome, can lead to poor quality eggs.

15 Sep 2010

Professor Nygren reviews current state of IVF safety

Now a review by the Chair of the international body which collects data on IVF concludes that IVF is generally safe, although he stresses that patients need to be made aware of the slight risks, and that we need to continue to monitor the results of the technique.

14 Sep 2010

U of A team on cusp of developing simple predictive test for preeclampsia

A team of researchers from the University of Alberta is on the cusp of developing a simple test to accurately predict which women will develop preeclampsia - a condition that affects 4 million women a year and can result in the deaths of both mothers and their babies.

14 Sep 2010

Structural component inside neurons dances when connections are strengthened

Scientists at Emory University School of Medicine have uncovered how a structural component inside neurons performs two coordinated dance moves when the connections between neurons are strengthened.

14 Sep 2010