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Researchers find gene sequences of MLV in chronic fatigue syndrome patients' blood samples

Researchers have found murine leukemia viruses (MLV) related gene sequences in blood samples collected from patients diagnosed with chronic fatigue syndrome (CFS) and some healthy blood donors, according to a study published online today by the scientific journal Proceedings of the National Academy of Sciences (PNAS).

24 Aug 2010

FDA approves Alexion's Rhode Island manufacturing facility as commercial supply source for Soliris

Alexion Pharmaceuticals, Inc. today announced that the US Food and Drug Administration (FDA) has approved Alexion's Rhode Island manufacturing facility (ARIMF) in Smithfield, Rhode Island as a second source of commercial supply for Soliris® (eculizumab).

23 Aug 2010

Researchers discover unusual property of meiosis may lead to Down syndrome

In a study of egg cells using time-lapse microscopy, researchers at the University of California, San Diego School of Medicine and the Ludwig Institute for Cancer Research have discovered an unusual property of meiosis - cell division that produces reproductive cells in sexually reproducing organisms.

23 Aug 2010

NCF announces formal disease model for Chronic Fatigue Syndrome

The National CFIDS Foundation Inc., of Needham Mass, has announced its formal disease model for Chronic Fatigue Syndrome (CFS) also known as Chronic Fatigue Immune Dysfunction Syndrome (CFIDS) as well as Myalgic Encephalomyelitis (ME). According to the NCF, a subgroup of patients with CFS fit a unique disease profile based on a model for a radioactive toxin.

21 Aug 2010

Research finds association between pain quality and patient functioning in carpal tunnel syndrome

For carpal tunnel syndrome sufferers, itching and throbbing are pain qualities most responsible for impaired functioning and sleep disruption, according to new research reported in The Journal of Pain.

21 Aug 2010

FDA extends review on Acetadote for non-acetaminophen acute liver failure

Cumberland Pharmaceuticals Inc. today announced the U.S. Food and Drug Administration (FDA) has extended its review of the supplemental new drug application (sNDA) for the use of Acetadote® (acetylcysteine) Injection in patients with non-acetaminophen acute liver failure.

21 Aug 2010

NSF issues award to develop techniques for analyzing children's behavior

A team led by the Georgia Institute of Technology has received a $10 million "Expeditions in Computing" award from the National Science Foundation (NSF) to develop novel computing techniques for measuring and analyzing the behavior of children.

20 Aug 2010

Research on gut mucosa enables effective drug treatment for irritable bowel syndrome

Irritable bowel syndrome makes life miserable for those affected an estimated ten percent or more of the population. And what irritates many of them even more is that they often are labeled as hypochondriacs, since physical causes for irritable bowel syndrome have never been identified. Now, biologists at the Technische Universitaet Muenchen (TUM) have shed new light on the matter: They have discovered mini-inflammations in the mucosa of the gut, which upset the sensitive balance of the bowel and are accompanied by sensitization of the enteric nervous system.

20 Aug 2010

Enteric microbiome affects disease susceptibility, provides therapeutic target for food-borne diseases: Research

At any given time, trillions of tiny microbes some helpful, some harmful are living on and in humans, forming communities and outnumbering the body's own cells tenfold. Using a $7.3 million federal grant that establishes a new cooperative research center at Michigan State University, a group of investigators is studying the microbes that live in our intestines, analyzing the role they play in food- and water-borne illnesses that kill millions of people each year worldwide.

20 Aug 2010

Celgene receives Japan's MHLW approval for REVLIMID in deletion 5q myelodysplastic syndrome patients

Celgene International Sàrl announced that REVLIMID (lenalidomide) has been granted full marketing authorization by Japan's Ministry of Health, Labour and Welfare (MHLW) for the treatment of patients with myelodysplastic syndromes (MDS) associated with a deletion 5q cytogenic abnormality. REVLIMID was also approved in June 2010 in combination with dexamethasone, for the treatment of patients with relapsed or refractory multiple myeloma who have received at least one prior standard therapy.

20 Aug 2010

Chelsea Therapeutics announces new investigator to conduct phase II clinical study of Droxidopa

Chelsea Therapeutics International, Ltd. announced that a new investigator-led phase II clinical study of Droxidopa, an oral synthetic precursor of norepinephrine, has been initiated in chronic fatigue syndrome (CFS).

20 Aug 2010

Decline in SIDS rate contributes to overall infant mortality reduction in New Jersey

The rate of Sudden Infant Death Syndrome (SIDS), a leading cause of infant mortality, declined in New Jersey by 45 percent between 2000 and 2006, the most recent year for which final SIDS data are available, report Barbara M. Ostfeld, PhD, and Thomas Hegyi, MD, professors in the Department of Pediatrics at UMDNJ-Robert Wood Johnson Medical School and program director and medical director, respectively, for the Sudden Infant Death Syndrome (SIDS) Center of New Jersey.

19 Aug 2010

Study finds burnout progressively develops among medical students

More than 40 percent of third-year medical students have symptoms of moderate to severe burnout, according to a study in the August Southern Medical Journal, official journal of the Southern Medical Association.

19 Aug 2010

Celera Corporation releases review article on KIF6 gene variant for CHD

Celera Corporation today announced the publication of a review article on the KIF6 gene variant as a predictor of risk of coronary heart disease (CHD) and reduction of CHD events from statin therapy.

19 Aug 2010

Deficiencies in DNA loop formation can cause multiple diseases: Research

The genes that are responsible for maintaining each cell type form DNA loops that link control elements for these genes. This surprising genome structure is generated and reinforced by two essential protein complexes that bridge the loops and contribute to proper gene regulation.

19 Aug 2010

Bolder BioTechnology receives $600,000 NIH SBIR grant to study long-acting IL-11 analog in ARS

Bolder BioTechnology, Inc. today announced that it has been awarded a Phase I Small Business Innovation Research (SBIR) grant totaling $600,000 from the National Institute of Allergy and Infectious Diseases (NIAID) of The National Institutes of Health (NIH). The grant will be used to demonstrate the feasibility of using our novel, long-acting IL-11 analog to accelerate platelet recovery and improve survival in a mouse model of Acute Radiation Syndrome (ARS).

18 Aug 2010

Study finds pharmaceuticals as a two-tier market for producing 'lemons' and serious harm

The pharmaceutical industry is a "market for lemons," a market in which the seller knows much more than the buyer about the product and can profit from selling products less effective and less safe than consumers are led to believe, according to an analysis that will be presented at the 105th Annual Meeting of the American Sociological Association.

18 Aug 2010

Genome-wide study identifies key genetic variant associated with nonalcoholic fatty liver disease

Researchers at Massachusetts General Hospital found that patients with nonalcoholic fatty liver disease (NAFLD) who carry an allele of the PNPLA3 gene have an increased risk of developing advanced disease, including nonalcoholic steatohepatitis (NASH), fibrosis, and cirrhosis. A second study supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) validates these findings and further concludes that in pediatric patients, the same allele is associated with earlier disease presentation.

18 Aug 2010

Research confirms genetic link to advanced fatty liver disease

17 Aug 2010

TRI awarded RSC contract to support domestic, international clinical research programs

Technical Resources International, Inc. is pleased to announce that TRI has been awarded the Regulatory Support Center contract by the U.S. National Institute of Allergy and Infectious Diseases of the U.S. National Institutes of Health, Department of Health and Human Services.

17 Aug 2010

Syndrome News and Research

Researchers find gene sequences of MLV in chronic fatigue syndrome patients' blood samples

FDA approves Alexion's Rhode Island manufacturing facility as commercial supply source for Soliris

Researchers discover unusual property of meiosis may lead to Down syndrome

NCF announces formal disease model for Chronic Fatigue Syndrome

Research finds association between pain quality and patient functioning in carpal tunnel syndrome

FDA extends review on Acetadote for non-acetaminophen acute liver failure

NSF issues award to develop techniques for analyzing children's behavior

Research on gut mucosa enables effective drug treatment for irritable bowel syndrome

Enteric microbiome affects disease susceptibility, provides therapeutic target for food-borne diseases: Research

Celgene receives Japan's MHLW approval for REVLIMID in deletion 5q myelodysplastic syndrome patients

Chelsea Therapeutics announces new investigator to conduct phase II clinical study of Droxidopa

Decline in SIDS rate contributes to overall infant mortality reduction in New Jersey

Study finds burnout progressively develops among medical students

Celera Corporation releases review article on KIF6 gene variant for CHD

Deficiencies in DNA loop formation can cause multiple diseases: Research

Bolder BioTechnology receives $600,000 NIH SBIR grant to study long-acting IL-11 analog in ARS

Study finds pharmaceuticals as a two-tier market for producing 'lemons' and serious harm

Genome-wide study identifies key genetic variant associated with nonalcoholic fatty liver disease

Research confirms genetic link to advanced fatty liver disease

TRI awarded RSC contract to support domestic, international clinical research programs

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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