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Study suggests SARS-CoV-2 is undergoing evolutionary changes at the functional RNA level in addition to the amino acid level

Researchers demonstrated SARS-CoV-2 evolution at the transcriptional level.

22 Apr 2022

Antibody-based treatment, endogenous immune responses, and within-host SARS-CoV-2 evolution in immunocompromised patients

Researchers investigated the interplay of all the factors responsible for within-host evolution of SARS-CoV-2 variants in immunocompromised patients.

21 Apr 2022

Evolution of SARS-CoV-2 variants

Research has demonstrated the evolutionary process and biology of SARS-CoV-2, the causative pathogen of the COVID-19 pandemic.

21 Apr 2022

Study evaluates SARS-CoV-2 whole genome data from patients and staff in the VA Northeast Ohio Healthcare System

Researchers surveyed over 360 COVID-19 patients to characterize the SARS-CoV-2 genomic sequence diversity of individual infections.

21 Apr 2022

Intranasal nanoparticle STING agonist with immunoantiviral activity against SARS-CoV-2 variants

Researchers developed an immunoantiviral, NanoSTING, and demonstrated its broad-spectrum antiviral properties in hamsters and mice.

21 Apr 2022

Advancements in HIV science

As far as viruses go, human immunodeficiency virus (HIV) is quite simple. About 100,000 times smaller than a red blood cell, the virus expresses just a dozen proteins, yet it can establish a lifelong infection that, if left untreated, causes acquired immunodeficiency syndrome (AIDS) and death.

20 Apr 2022

New technology enables single-cell sorting based on functional outputs

For nearly 40 years, drugmakers have used genetically engineered cells as tiny drug factories. Such cells can be programmed to secrete compounds that yield drugs used to treat cancer and autoimmune conditions such as arthritis.

20 Apr 2022

Novel approach to identify targets for Wolbachia-based dengue control

Dengue is the most widespread mosquito-borne disease in the world, and to date, there are no medical treatments for people suffering from this disease.

19 Apr 2022

Scientists create a bioengineered 3D model that mimics the biology of two rare neuromuscular diseases

A scientific team supported by the National Institutes of Health has created a tiny, bioengineered 3-D model that mimics the biology of chronic inflammatory demyelinating polyneuropathy and multifocal motor neuropathy, a pair of rare, devastating neuromuscular diseases.

19 Apr 2022

Small genetic differences can affect the ability to utilize energy of various nutrients, study finds

Carbohydrates, proteins and fats are essential nutrients to all animals. Yet dietary variation between species, populations and individuals can vary dramatically.

19 Apr 2022

New, longest documented case of persistent acute SARS-CoV-2 infection

Researchers describe a 16-month-old case of SARS-CoV-2 infection in an immunocompromised individual.

18 Apr 2022

SARS-CoV-2 infection patterns in olfactory epithelium

Researchers assess changes in the respiratory and olfactory epithelium of the nasal mucosa in SARS-CoV-2 infections by the WA1, Delta, and Omicron strains.

18 Apr 2022

Genomic characterization of the circulating SARS-CoV-2 lineages in Papua New Guinea

A recent study characterized the SARS-CoV-2 lineages circulating in Papua New Guinea during the second wave of COVID-19.

15 Apr 2022

Booster dose of mRNA vaccine highly effective in preventing SARS-CoV-2 infection

A booster dose of mRNA vaccine significantly decreases the risk of being infected with either the delta or omicron COVID-19 variants, according to scientists at the Rocky Mountain Center for Occupational and Environmental Health (RMCOEH), a program partnership between the University of Utah and Weber State University.

14 Apr 2022

Study explores role of APOBEC-mediated RNA editing in SARS-CoV-2 fitness

A new study investigated whether APOBEC proteins can directly edit the RNA sequence of SARS-CoV-2 to generate C-to-U mutations.

14 Apr 2022

People with COVID-19 can shed viral RNA in their feces months after initial infection

The extended presence of viral RNA in feces, but not respiratory samples, along with the association of fecal viral RNA shedding with GI symptoms suggest that SARS-CoV-2 infects the GI tract, and that this infection can be prolonged in a subset of individuals with COVID-19.

13 Apr 2022

The transmission dynamics of key SARS-CoV-2 mutations revealed by subtyping in new study

In a new study, researchers devised a method for reducing the size of a large collection of SARS-CoV-2 genomes by combining correlated single nucleotide variation sets with allelic association.

13 Apr 2022

Researchers publish consensus statement for the study of recalled experiences surrounding death

Scientific advances in the 20th and 21st centuries have led to a major evolution in the understanding of death. At the same time, for decades, people who have survived an encounter with death have recalled unexplained lucid episodes involving heightened consciousness and awareness.

13 Apr 2022

Zika virus can mutate to become more infective and dangerous, finds study

LA JOLLA, CA - Researchers at La Jolla Institute for Immunology (LJI) have found that Zika virus can mutate to become more infective - and potentially break through pre-existing immunity.

13 Apr 2022

Treg cell Notch receptors drive SARS-CoV-2-induced MIS-C

In a recent study under consideration at Nature Portfolio Journal and posted to the Research Square* preprint server, researchers demonstrated the evolution of multi-system inflammatory syndrome in children (MIS-C) following acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

12 Apr 2022

Evolution News and Research

Study suggests SARS-CoV-2 is undergoing evolutionary changes at the functional RNA level in addition to the amino acid level

Antibody-based treatment, endogenous immune responses, and within-host SARS-CoV-2 evolution in immunocompromised patients

Evolution of SARS-CoV-2 variants

Study evaluates SARS-CoV-2 whole genome data from patients and staff in the VA Northeast Ohio Healthcare System

Intranasal nanoparticle STING agonist with immunoantiviral activity against SARS-CoV-2 variants

Advancements in HIV science

New technology enables single-cell sorting based on functional outputs

Novel approach to identify targets for Wolbachia-based dengue control

Scientists create a bioengineered 3D model that mimics the biology of two rare neuromuscular diseases

Small genetic differences can affect the ability to utilize energy of various nutrients, study finds

New, longest documented case of persistent acute SARS-CoV-2 infection

SARS-CoV-2 infection patterns in olfactory epithelium

Genomic characterization of the circulating SARS-CoV-2 lineages in Papua New Guinea

Booster dose of mRNA vaccine highly effective in preventing SARS-CoV-2 infection

Study explores role of APOBEC-mediated RNA editing in SARS-CoV-2 fitness

People with COVID-19 can shed viral RNA in their feces months after initial infection

The transmission dynamics of key SARS-CoV-2 mutations revealed by subtyping in new study

Researchers publish consensus statement for the study of recalled experiences surrounding death

Zika virus can mutate to become more infective and dangerous, finds study

Treg cell Notch receptors drive SARS-CoV-2-induced MIS-C

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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