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Study suggests a new improved treatment option for children with Hurler's syndrome

Researchers have transplanted genetically modified hematopoietic stem cells into mice so that their developing red blood cells produce a critical lysosomal enzyme - preventing or reducing organ and central nervous system damage from the often-fatal genetic disorder Hurler's syndrome.

10 Nov 2009

Prostatitis is a psychoneuromuscular condition: Study

In the November 2009 issue of the Journal of Urology, Stanford Medical School researcher Dr. Rodney Anderson and researchers at the National Center for Pelvic Pain Research, in a new study, demonstrated a high correlation between the location of painful trigger points inside the pelvic floor muscles of men with chronic prostatitis and the location in the body where they routinely complain of pain.

10 Nov 2009

Astellas receives exclusive rights to develop and commercialize linaclotide compound in Asia

Ironwood Pharmaceuticals, Inc. and Astellas Pharma Inc. today announced that they have entered into an agreement providing Astellas exclusive rights to develop and commercialize the investigational compound linaclotide in Japan, Indonesia, Korea, the Philippines, Taiwan, and Thailand.

10 Nov 2009

TessArae introduces new integrated product solutions for testing human genetic disease

TessArae® LLC, a global leader in resequencing microarray-based applications, announces the launch of new integrated product solutions for genetic testing of the mutations that underlie human hereditary diseases. The combination of TessArae's expertise in microarray-based resequencing with novel nucleotide sequence basecalling algorithms and analysis software enables screening for all targeted mutations in multiple genes of a syndrome or disorder simultaneously.

10 Nov 2009

Children and young people with autism should be offered special teaching support

Teachers and parents must be vigilant in observing difficulties with language comprehension, reading and spelling in children and young people with autism, Asperger's syndrome and ADHD.

10 Nov 2009

EpiCept announces third quarter 2009 financial results

EpiCept Corporation today announced operating and financial results for the three and nine months ended September 30, 2009, and provided an update on Ceplene® and several of the Company’s key product candidates.

10 Nov 2009

Covidien contraindicates use of its Optimark gadoversetamide injection

Covidien, a leading global provider of healthcare products, today announced that it will voluntarily contraindicate the use of its Optimark™ gadoversetamide injection, a gadolinium-based contrast agent (GBCA), in magnetic resonance imaging (MRI) procedures involving patients with severe renal impairment.

9 Nov 2009

Winner of the 2009 Women in Cardiology Mentoring Award

C. Noel Bairey Merz, M.D., an internationally recognized authority on women's heart health, will receive the American Heart Association's 2009 Women in Cardiology Mentoring Award at the organization's Scientific Sessions 2009, to be held in Orlando at the Orange County Convention Center Nov. 14-Nov. 18.

7 Nov 2009

Neurogen announces financial results for the third quarter of 2009

Neurogen Corporation, a drug development company historically focused on drugs for psychiatric and neurological disorders, today announced financial and operating results for the quarter ended September 30, 2009.

6 Nov 2009

Long QT syndrome study reveals importance of genetic testing's role in diagnosing disease

Results of a long QT syndrome (LQTS) study published in the current issue of Circulation play an important role in understanding genetic testing's role in diagnosing disease, according to the senior author, Michael Ackerman, M.D., Ph.D. A pediatric cardiologist at Mayo Clinic, Dr. Ackerman directs Mayo's Long QT Syndrome Clinic and is the director of the Mayo Clinic Windland Smith Rice Sudden Death Genomics Laboratory.

6 Nov 2009

Successful leukemia treatment with a radiolabeled antibody followed by stem cell transplant

For the first time, researchers at Fred Hutchinson Cancer Research Center have reported the use of a radiolabeled antibody to deliver targeted doses of radiation, followed by a stem cell transplant, to successfully treat a group of leukemia and pre-leukemia patients for whom there previously had been no other curative treatment options.

6 Nov 2009

Can American ginseng relieve health problems?

With the current outbreak of influenza-like illnesses, many people are trying to boost their immune systems with supplements. Ginseng is often a key ingredient, but its therapeutic use may extend far beyond that. Researchers are now investigating whether ginseng can help relieve health problems ranging from diabetes to depression to erectile dysfunction.

5 Nov 2009

Higher testosterone levels in older women are associated with increased health risks

Postmenopausal women who have higher testosterone levels may be at greater risk of heart disease, insulin resistance and the metabolic syndrome compared to women with lower testosterone levels, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

4 Nov 2009

Hospitalization and death of H1N1 patients can occur at all ages, says study

In contrast with some common perceptions regarding 2009 influenza A(H1N1) infections, an examination of cases in California indicates that hospitalization and death can occur at all ages, and about 30 percent of hospitalized cases have been severe enough to require treatment in an intensive care unit, according to a study in the November 4 issue of JAMA.

4 Nov 2009

Breastfeeding: ADA position paper details health benefits for both infants and mothers

The American Dietetic Association has released an updated position paper on breastfeeding that details health benefits for both infants and mothers and encourages promotion of breastfeeding whenever possible.

4 Nov 2009

$3.9 million Challenge grant for Thomas Jefferson researchers

Four researchers from Thomas Jefferson University have received $3.9 million in Challenge grant funds as part of the American Recovery and Reinvestment Act.

3 Nov 2009

Caucasian women may suffer from RLS up to four times more than African-American women

New research shows that Caucasian women may suffer from restless legs syndrome (RLS), a sleep disorder characterized by the strong urge to move the legs, up to four times more than African-American women. The study, presented at CHEST 2009, the 75th annual international scientific assembly of the American College of Chest Physicians (ACCP), found that, overall, non-African-American (NAA) patients experienced RLS four times more often than African-Americans (AA).

3 Nov 2009

Seaside Therapeutics commences STX107 Phase 1 clinical trial for Fragile X Syndrome

Seaside Therapeutics LLC today announced that the Company has initiated a Phase 1 clinical trial of STX107, a highly potent, selective mGluR5 antagonist, in development for the treatment of Fragile X Syndrome. The single ascending dose study is designed to evaluate the safety, tolerability and pharmacokinetics of STX107 in healthy volunteers. Fragile X Syndrome is the most common inherited form of mental impairment and the most common known cause of autism.

3 Nov 2009

Phase 1 study of STX107 for Fragile X syndrome begins

NIH-supported scientists at Seaside Therapeutics in Cambridge, Mass., are beginning a clinical trial of a potential medication designed to correct a central neurochemical defect underlying Fragile X syndrome, the most common inherited cause of intellectual disability. There has to date been no medication that could alter the disorder's neurologic abnormalities. The study will evaluate safety, tolerability, and optimal dosage in healthy volunteers.

3 Nov 2009

High prevalence of nocturnal teeth grinding in patients with OSA

There is a high prevalence of nocturnal teeth grinding, or bruxism, in patients with obstructive sleep apnea (OSA), particularly in Caucasians. New research presented at CHEST 2009, the 75th annual international scientific assembly of the American College of Chest Physicians (ACCP), found that nearly 1 in 4 patients with OSA suffers from nighttime teeth grinding; this seems to be especially more prevalent in men and in Caucasians compared with other ethnic groups.

3 Nov 2009

Syndrome News and Research

Study suggests a new improved treatment option for children with Hurler's syndrome

Prostatitis is a psychoneuromuscular condition: Study

Astellas receives exclusive rights to develop and commercialize linaclotide compound in Asia

TessArae introduces new integrated product solutions for testing human genetic disease

Children and young people with autism should be offered special teaching support

EpiCept announces third quarter 2009 financial results

Covidien contraindicates use of its Optimark gadoversetamide injection

Winner of the 2009 Women in Cardiology Mentoring Award

Neurogen announces financial results for the third quarter of 2009

Long QT syndrome study reveals importance of genetic testing's role in diagnosing disease

Successful leukemia treatment with a radiolabeled antibody followed by stem cell transplant

Can American ginseng relieve health problems?

Higher testosterone levels in older women are associated with increased health risks

Hospitalization and death of H1N1 patients can occur at all ages, says study

Breastfeeding: ADA position paper details health benefits for both infants and mothers

$3.9 million Challenge grant for Thomas Jefferson researchers

Caucasian women may suffer from RLS up to four times more than African-American women

Seaside Therapeutics commences STX107 Phase 1 clinical trial for Fragile X Syndrome

Phase 1 study of STX107 for Fragile X syndrome begins

High prevalence of nocturnal teeth grinding in patients with OSA

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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