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NIH grant to fund development of new gene therapy platform for brain diseases

A two-phase NIH grant will fund research into a new CRISPR-based gene therapy platform that will target genetic brain diseases like Angelman syndrome and H1-4 (HIST1H1E) syndrome.

3 Oct 2023

SARS-CoV-2 infection in coronary vessels linked to cardiovascular complications

Researchers reported that the increased long-term risk of acute cardiovascular complications associated with COVID-19 is linked to SARS-CoV-2 infecting coronary vessels and inducing the formation of plaques.

3 Oct 2023

Could seaweeds be the superfood and medicine of the future?

Researchers consolidate the diverse nutritional and medicinal benefits of seaweeds, touting their potential in food, nutraceuticals, and pharmaceuticals. The study also highlights challenges and opportunities in industrial applications, calling for more research to optimize extraction and refinement processes.

2 Oct 2023

Long COVID unmasked: Patients share varied physical, mental, and social challenges

Patient experiences of the post-acute sequelae of coronavirus disease 2019 (COVID-19) or long COVID.

2 Oct 2023

Benefits of postpartum dietary intervention on weight management in obese women

Researchers explore the effects of a dietary intervention in postpartum women with higher body mass index.

2 Oct 2023

New study reveals BA.2.86 subvariant's surprising dance with antibodies

Researchers examined the antigenicity of the emerging SARS-CoV-2 subvariant BA.2.86, finding that it is not resistant to neutralizing antibodies from previously infected or vaccinated individuals, although it does show increased binding affinity to the ACE-2 receptor. The study highlights the subvariant's sensitivity and resistance to different classes of monoclonal antibodies, offering insights for future treatment and vaccine development.

2 Oct 2023

Ginger shows promise as a natural defense against autoimmune diseases

Comprehensive study reveals that whole ginger extracts have a significant impact on inhibiting neutrophil hyperactivity, a key factor in autoimmune diseases like APS and lupus. Consuming ginger for just a week showed promising results in both animal models and human trials, positioning it as a natural and affordable treatment option for a range of autoimmune disorders.

2 Oct 2023

Maternal COVID-19 shots significantly lowered infant hospitalizations during Omicron wave

Study found that maternal COVID-19 vaccination during pregnancy significantly reduces the risk of COVID-19-related hospitalizations in infants under six months, particularly boosting protection during the first three months of life. With 78% of the hospitalized infants born to unvaccinated mothers, the research emphasizes the crucial role of maternal vaccination in safeguarding infants too young for vaccination.

2 Oct 2023

New study reveals alarming cardiovascular risks from COVID

The study published in Nature Cardiovascular Research reveals that SARS-CoV-2, the virus causing COVID-19, can directly infect coronary vessels and arterial plaques, heightening the risk of cardiovascular complications like heart attacks and strokes. These findings offer critical insights into the increased long-term cardiovascular risks for COVID-19 survivors and open new avenues for targeted therapies.

1 Oct 2023

Is long COVID triggering irritable bowel syndrome? Arizona study to investigate

The Arizona CoVHORT research study at the University of Arizona has received $3.2 million in funding to investigate the links between long COVID and gastrointestinal symptoms, specifically irritable bowel syndrome (IBS). Led by epidemiologist Kristen Pogreba-Brown, the study aims to determine how COVID-19 impacts the incidence of IBS, offering potential benefits to millions affected by the ongoing pandemic.

1 Oct 2023

Brigham researchers quantify the burden of SARS-CoV-2-associated sepsis

Using data from Mass General Brigham's electronic health records, Brigham researchers quantified the burden of SARS-CoV-2-associated sepsis early in the pandemic.

29 Sep 2023

Researchers develop an improved way to test potential vaccines against bird flu

Researchers from the University of Pittsburgh and the National Institutes of Health (NIH) Vaccine Research Center have developed an improved way to test potential vaccines against bird flu. The report was published this week in the journal iScience.

29 Sep 2023

SARS-CoV-2 accounted for 1 in 6 cases of sepsis during early months of the pandemic

SARS-CoV-2 accounted for 1 in 6 cases of sepsis during the first 33 months of the COVID-19 pandemic, highlighting the importance of viral sepsis, according to a new study led by researchers at the Harvard Pilgrim Health Care Institute.

29 Sep 2023

Aerosolized ACE2 neutralizes COVID-19 variants in lab and mice tests

Researchers from the University of Texas Southwestern have developed an aerosolized, mutated form of ACE2 that effectively neutralizes various SARS-CoV-2 variants in both cell cultures and mice. The study suggests that this modified ACE2 has promising preventive and therapeutic potential against COVID-19, especially with its easy aerosolized administration.

28 Sep 2023

Challenges and opportunities for better lung cancer care for the elderly

A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 17, entitled, "Promising trends in lung cancer care, but are we overlooking the majority?"

28 Sep 2023

Primate model unlocks clues to long-COVID's impact on blood sugar, hints at vaccine benefits

The study uses a non-human primate model to explore the link between long-COVID and disruptions in glucose metabolism, finding a positive correlation. Vaccination appeared to improve glycemic control, suggesting a possible role in managing long-COVID symptoms.

28 Sep 2023

Vaxzevria vaccine boosts mucosal immunity in COVID-19 recovered

Study highlights the ability of the Vaxzevria vaccine in inducing robust mucosal antibody responses, especially in COVID-19-recovered individuals, showcasing a notable defense against various SARS-CoV-2 variants. However, it emphasizes the need for booster doses to enhance anti-SARS-CoV-2 mucosal immunity, especially in infection-naïve individuals, to broaden protection against emerging viral variants.

28 Sep 2023

New framework for ethical microbiome research practices that include Indigenous communities

Every person hosts trillions of microorganisms, like bacteria and viruses, on their skin and in organs including those that make up the digestive tract, like their mouth, that collectively make up their microbiome.

28 Sep 2023

Non-alcoholic fatty liver disease linked to higher risk of blood clots in healthy adults

Recent study in Scientific Reports finds a link between nonalcoholic fatty liver disease (NAFLD) and a higher risk of venous thromboembolism (VTE) among healthy Korean adults. The research suggests that NAFLD may contribute to a hypercoagulable state, increasing the risk of VTE.

27 Sep 2023

Zoonotic spillover safeguarding: computationally designed antigen targets range of coronaviruses

Researchers used an interdisciplinary approach incorporating phylogenetics, 3D protein modeling, and plasmid design to identify and computationally design an antigen representing the core of most currently known sarbecoviruses.

27 Sep 2023