Fistula News and Research

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A Fistula is an abnormal opening or passage between two organs or between an organ and the surface of the body. Fistulas may be caused by injury, infection, or inflammation, or may be created during surgery.

Urologists report success using robot-assisted surgery for urinary abnormality

Ashok Hemal, M.D., a urologic surgeon from Wake Forest University Baptist Medical Center, and colleagues have reported success using robot-assisted laparoscopic surgery to repair abnormal openings between the bladder and vagina known as fistulas. Reporting on their experience with seven patients, Hemal and colleagues have the world's largest known success with the procedure.

18 Aug 2008

Reducing blockage fails to improve access to the bloodstream for kidney dialysis

Reducing early blockages in bloodstream access for kidney failure treatment does not increase the likelihood that the access will function adequately for long-term treatments, according to a study funded by the National Institutes of Health. Results were published May 14, 2008, in the Journal of the American Medical Association.

22 May 2008

FDA approves Cimzia as treatment for Crohn's disease

A new drug has been approved to help sufferers of Crohn's disease, the U.S. Food and Drug Administration announced today. Cimzia (certolizumab pegol) received approval for adults with moderate to severe Crohn's disease who have not responded to conventional therapies. This product was approved with a Medication Guide.

22 Apr 2008

Genentech updates on phase III study of Avastin plus chemo in first-line, advanced, non-squamous, non-small cell lung cancer

Genentech, Inc. has announced an update for the previously reported Roche-sponsored international Phase III clinical study (AVAiL) of Avastin (bevacizumab) in combination with gemcitabine and cisplatin chemotherapy, in patients with advanced, non-squamous, non-small cell lung cancer (NSCLC).

21 Apr 2008

New method of pancreaticojejunostomy with a fast-absorbable suture material

A soft pancreatic texture with a narrow pancreatic ductal size creates a high risk for the development of a pancreatic fistula after pancreaticoduodenectomy, often leading to death.

19 Mar 2008

Unusual case of upper obstructive syndrome

Aorto-duodenal fistulae (ADF) are the most frequent aorto-enteric fistulae (80%) and the most frequent presenting sign of ADF is upper gastrointestinal bleeding (UGI).

25 Feb 2008

Asian women at risk for congenital aneurismal fistulas

A seemingly random arterial abnormality that can cause heart attack and sudden death in adults with no previous symptoms may not be so random after all.

8 Feb 2008

FDA approves Tysabri to treat Crohn's disease

The U.S. Food and Drug Administration has approved Tysabri (natalizumab) for the treatment of moderate-to-severe Crohn's disease in patients with evidence of inflammation who have had an inadequate response to, or are unable to tolerate, conventional Crohn's disease therapies.

14 Jan 2008

New robotic surgery technique appears promising for the removal of cancer in tonsils

Typically, surgeons trying to remove tonsils of patients with cancer through the mouth have limited access to the area, according to background information in the article. If the cancer has spread to any of the surrounding tissues, an open approach involving cutting through the skin is needed. These procedures take a long time, can cause long-term difficulty swallowing and usually require the placement of a tracheotomy tube.

18 Dec 2007

Avastin (bevacizumab) shows promise in phase II study of glioblastoma multiforme

Genentech, Inc. has announced that both study arms of a randomized, multi-center Phase II clinical study of Avastin (bevacizumab) administered alone or in combination with irinotecan chemotherapy demonstrated encouraging six-month progression-free survival (PFS) and objective response rate in patients with relapsed glioblastoma multiforme (GBM), the most common and aggressive type of brain cancer.

19 Nov 2007

Endosonography-guided biliary drainage is useful in cases with failed endoscopic biliary stenting

The role of endosonography (ES) in digestive diseases is expanding gradually from diagnostic applications to therapeutic ones. The feasibility of ES-guided cholangiopancreatography was first reported by Harada et al. (pancreatography) and Wiersema et al. (cholangiography) in 1995 and 1996, respectively.

5 Nov 2007

New devices and trials for the treatment and prevention of dialysis access stenosis

Having a healthy kidney is worth a billion dollars. But an unhealthy kidney costs more - about $16 billion more, according to Prabir Roy-Chaudhury, MD, PhD, associate professor in the division of nephrology and hypertension at the University of Cincinnati (UC).

13 Sep 2007

Staggering costs of end-stage renal disease in U.S.

Recent progress in the prevention and treatment of end-stage renal disease (ESRD) in the United States give reason for "cautious optimism," but skyrocketing costs are a major concern, according to a Special Article in the October Journal of the American Society of Nephrology.

12 Aug 2007

Correcting birth defects

Traditionally when a baby was born with a malformation of the lung or esophagus, they had to undergo open surgery involving a large chest incision with risk for serious complications.

18 Jul 2007

New genetic risk factors for Crohn's disease

An international research team , including investigators from Massachusetts General Hospital (MGH) and the Broad Institute of Harvard University and Massachusetts Institute of Technology, has identified several novel genetic variations associated with the risk of Crohn's disease.

16 Apr 2007

Severe complications from circumcision

A study by Ceylan, et al from Turkey evaluated their experience in 48 cases of severe complications of circumcisions.

14 Apr 2007

Obstetric fistula, impact on women

Reuters on Friday examined obstetric fistula and its impact on women living with the condition (Ringler, Reuters, 3/30). Obstetric fistulas develop when a fetus becomes lodged during labor in the narrow birth canal of a girl or young woman, causing pressure that blocks the flow of blood to vital tissues and tearing holes in the bowel, urethra or both, causing incontinence.

3 Apr 2007

Response to opinion piece saying global maternal health programs deserve more support

The New York Times on Sunday published several letters to the editor in response to a Feb. 25 Times column by Nicholas Kristof. According to Kristof, maternal health programs should receive support from the U.S. in part because the country knows how to lower maternal mortality and morbidity.

8 Mar 2007

FDA approves Humira (adalimumab) for Crohn's disease

The U.S. Food and Drug Administration (FDA) today approved Humira (adalimumab) to treat adult patients with moderately to severely active Crohn's disease, a chronic inflammatory disease of the intestines, which affects an estimated one million Americans.

27 Feb 2007

Global maternal health programs deserve 'far more support' from U.S. government

Maternal health programs "deserve far more support" from the U.S. in part because the country knows "exactly what to do to bring down maternal mortality and morbidity," New York Times columnist Nicholas Kristof writes in an opinion piece.

27 Feb 2007