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Lab-grown tumor organoids predict patient response to CAR T cell therapy

For the first time, researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM) to accurately model a patient's response to CAR T cell therapy in real time.

9 Dec 2024

New brain stimulation trial aims to improve cognitive recovery from TBI

Traumatic brain injury (TBI) is a leading cause of death and disability among young people in the United States and is the most devastating survivable injury in modern warfare, according to the University of Cincinnati's Ishita Basu.

9 Dec 2024

PAGER technology unlocks new potential for controlling cellular activity

A basic function of cells is that they act in response to their environments. It makes sense, then, that a goal of scientists is to control that process, making cells respond how they want to what they want.

5 Dec 2024

Human ability to process numbers traced to unexpected brain region

New research reveals the unique human ability to conceptualize numbers may be rooted deep within the brain.

3 Dec 2024

Men face sharper brain aging from obesity and heart risks

Obesity and cardiovascular risk factors accelerate brain volume loss, with males experiencing earlier and more significant impacts, highlighting the importance of early interventions to prevent neurodegeneration.

1 Dec 2024

Cardiovascular disease risk linked to early brain decline in men

Men with cardiovascular disease risk factors, including obesity, face brain health decline a decade earlier - from their mid 50s to mid 70s - than similarly affected women who are most susceptible from their mid 60s to mid 70s, suggest the findings of a long term study, published online in the Journal of Neurology Neurosurgery & Psychiatry.

26 Nov 2024

NREM sleep boosts cognitive performance through brain synchronization

While it's well known that sleep enhances cognitive performance, the underlying neural mechanisms, particularly those related to nonrapid eye movement (NREM) sleep, remain largely unexplored.

23 Nov 2024

Adjunctive middle meningeal artery embolization reduces treatment failure for chronic subdural hematoma

New research by Society of Neurolnterventional Surgery (SNIS) members found that adjunctive middle meningeal artery embolization (MMAE) for the treatment of chronic subdural hematoma (CSDH) resulted in a lower risk of treatment failure than standard treatment alone, without resulting in an increased incidence of disabling stroke or death in the short term.

22 Nov 2024

Novel combination of surgery and embolization reduces recurrence of subdural hematomas

A novel combination of surgery and embolization used to treat subdural hematomas, bleeding between the brain and its protective membrane due to trauma, reduces the risk of follow-up surgeries, according to researchers at Weill Cornell Medicine and University at Buffalo.

20 Nov 2024

Study defines three subtypes of Chiari type-1 malformation to guide treatment

Roughly 4% of the population is affected by a congenital brain malformation that has eluded researchers' efforts to find causes and treatments.

19 Nov 2024

Pulses of light show promise in controlling seizures

In what could one day become a new treatment for epilepsy, researchers at UC San Francisco, UC Santa Cruz and UC Berkeley have used pulses of light to prevent seizure-like activity in neurons.

15 Nov 2024

NYU Langone Health continues streak of "A" safety rating from Leapfrog

NYU Langone Health remains at the forefront of patient safety, with all of its inpatient locations earning "A" ratings from The Leapfrog Group, a national nonprofit watchdog organization focused on healthcare safety and quality.

15 Nov 2024

AI technique helps neurosurgeons detect hidden cancer during brain tumor surgery

Technique offers new hope for increased survival in patients with brain tumors.

13 Nov 2024

Early radiosurgery for small cranial nerve tumors can prevent future complications

Patients with a small cranial nerve tumor that can cause hearing loss, vertigo, imbalance and ringing in the ears have typically been watched rather than proactively treated, as the risks of early intervention were thought to outweigh the benefits.

12 Nov 2024

Barrow researchers display Andrea Vesalius' anatomical manikins for the first time

For the first time, researchers at Phoenix's Barrow Neurological Institute have collected and displayed together the "manikins" published nearly 500 years ago by the 16th Century anatomist Andrea Vesalius – works that laid the foundation for modern surgical and neurosurgical training.

4 Nov 2024

New targets identified for treating glioblastoma through genetic screen

A team led by researchers at the University of Toronto has uncovered new targets that could be the key to effectively treating glioblastoma, a lethal type of brain cancer.

4 Nov 2024

Black prostate cancer patients respond better to immunotherapy

Black men with advanced prostate cancer have a greater chance of survival after immunotherapy treatment, at least in part, because of ancestral gene variants in immune responses.

17 Oct 2024

Extrachromosomal DNA in more aggressive cancers could be targets for future therapies

Research published in Nature Genetics on Oct.14, by Yale Cancer Center researchers at Yale School of Medicine, found a higher concentration of a specific kind of DNA — extrachromosomal or ecDNA — in more aggressive and advanced cancers that could mark them as targets for future therapies.

15 Oct 2024

Study highlights delays in care for pediatric trauma patients

Severely injured children who are brought to an emergency medical department by their parents or carers are often not seen as quickly as those who arrive at the hospital via ambulance, according to findings presented at the European Emergency Medicine Congress on 14th October 2024.

14 Oct 2024

New magnetogenetics technology holds promise as a powerful tool for studying the brain

A new technology enables the control of specific brain circuits non-invasively with magnetic fields, according to a preclinical study from researchers at Weill Cornell Medicine, The Rockefeller University and the Icahn School of Medicine at Mount Sinai.

10 Oct 2024