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Blood samples from healthy individuals have pre-existing anti-SARS-CoV-2 IgGs and IVIg may be an effective therapy for severe COVID-19

A new paper introduces evidence of effective alleviation of disease severity using intravenous immunoglobulin (IVIg).

14 Nov 2022

Study suggests the rapid expansion of naïve T cells can provide a fast and effective immune response to SARS-CoV-2 and other viral infections

Researchers investigated the early T cell responses during SARS-CoV-2 infections to understand the mechanisms of rapid clonal expansion that characterize the T cell responses to acute infections and vaccinations.

14 Nov 2022

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

Researchers investigated the change in the stability, antigenicity, and protein expression of the SARS-CoV-2 spike protein trimer using structure-directed mutagenesis to alter a cavity in the core of the spike protein.

14 Nov 2022

SARS-CoV-2 detected in white-tailed deer in Canada

Researchers investigated the detection of SARS-CoV-2 in white-tailed deer.

14 Nov 2022

The viral fitness and antigenic relationship among Omicron sublineages

Researchers used mouse models and human airway cell cultures to investigate the relative viral replication rates and cross-neutralization against SARS-CoV-2 Omicron sublineages.

14 Nov 2022

Long-term humoral response and its determinants following 2- and 3-dose COVID-19 mRNA vaccines

Researchers compared the waning of vaccine-induced immunity from two and three doses of mRNA COVID-19 Pfizer-BioNTech vaccine BNT162b2 by conducting a repeated serological study to assess the prolonged humoral response.

14 Nov 2022

More adverse reactions following bivalent COVID-19 mRNA booster vaccine

A recent study posted to medRxiv* examined adverse reactions after administration of a bivalent BNT162b2 coronavirus disease 2019 (COVID-19) vaccine booster.

13 Nov 2022

Omicron BA.1/BA.2 breakthrough infection after 3-dose BNT162b2 vaccination provides improved protection against Omicron BA.5

In a recent study published in the Emerging Infectious Disease journal, researchers compared the neutralization associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.5 sublineage to Omicron BA.1/BA.2 sublineages among vaccinated and convalescent patients.

13 Nov 2022

How air pollution affects the central nervous system over time

An article published in the journal Toxics describes how air pollutants adversely impact the human nervous system.

13 Nov 2022

How lessons from the HIV epidemic can help combat COVID-19

Researchers revisit lessons learned from the HIV pandemic in response to COVID-19.

13 Nov 2022

Researchers receive NIH grant to develop mRNA vaccines to deter cancer development

A multidisciplinary team of Weill Cornell Medicine researchers have received a five-year $5.7 million grant from the National Cancer Institute at the National Institutes of Health to fund a center aimed at developing messenger RNA (mRNA) vaccines to deter cancer development in at-risk groups.

11 Nov 2022

Study shows the importance of preserving microglia and Sirt1 functional efficiency for longevity

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 20, entitled, "Age-associated changes in microglia activation and Sirtuin-1- chromatin binding patterns."

11 Nov 2022

What is the duration of persistent symptoms after SARS-CoV-2 infection, and what factors are associated with their resolution?

Researchers examined temporal dynamics of persistent symptom resolution following acute COVID-19 in the general population of France.

11 Nov 2022

Is placental antibody transfer after COVID-19 vaccination different from that after SARS-CoV-2 infection in pregnant individuals?

Researchers investigated the placental transfer ratios of anti-SARS-CoV-2 antibodies in pregnant females.

11 Nov 2022

‘Impending intergenerational crisis’: Americans with disabilities lack long-term care plans

Thinking about the future makes Courtney Johnson nervous. The 25-year-old blogger and college student has autism and several chronic illnesses, and with the support of her grandparents and friends, who help her access a complex network of social services, she lives relatively independently in Johnson City, Tennessee.

11 Nov 2022

Delay in consciousness in severe cases of COVID-19 may be caused by neural hibernation

An article published in the journal PNAS provides a conceptual analysis to interpret the brain state of coronavirus disease 2019 (COVID-19) patients experiencing prolonged recovery of consciousness.

10 Nov 2022

Mosaic nanoparticles displaying spike protein trimers from different coronaviruses elicits cross-reactive protection

In a recent study under review at the Nature Portfolio journal and currently posted to Research Square* preprint server, researchers developed and assessed the immunogenicity of nanoparticles expressing spike trimers from coronaviruses (CoVs).

10 Nov 2022

A knowledgebase of currently known categorized COVID-19 severity variants

In a recent study posted to the medRxiv* preprint server, researchers assessed human genome variants related to the susceptibility and severity of coronavirus disease 2019 (COVID-19).

10 Nov 2022

Study evaluates transcutaneous vagus nerve stimulation as treatment for long COVID-chronic fatigue

In a recent study posted to the medRxiv* server, researchers evaluated non-invasive transcutaneous vagus nerve stimulation [tVNS] as a treatment for long COVID-related chronic fatigue syndrome (CFS).

10 Nov 2022

People of all age groups are at risk of post-COVID-19 syndrome, study says

Following COVID-19 infection, there is significant new onset morbidity in children, adolescents and adults across 13 distinct diagnosis and symptom complexes, according to a new study publishing November 10th in the open access journal PLOS Medicine by Martin Roessler of Technische Universität Dresden, Germany, and colleagues.

10 Nov 2022

Syndrome News and Research

Blood samples from healthy individuals have pre-existing anti-SARS-CoV-2 IgGs and IVIg may be an effective therapy for severe COVID-19

Study suggests the rapid expansion of naïve T cells can provide a fast and effective immune response to SARS-CoV-2 and other viral infections

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

SARS-CoV-2 detected in white-tailed deer in Canada

The viral fitness and antigenic relationship among Omicron sublineages

Long-term humoral response and its determinants following 2- and 3-dose COVID-19 mRNA vaccines

More adverse reactions following bivalent COVID-19 mRNA booster vaccine

Omicron BA.1/BA.2 breakthrough infection after 3-dose BNT162b2 vaccination provides improved protection against Omicron BA.5

How air pollution affects the central nervous system over time

How lessons from the HIV epidemic can help combat COVID-19

Researchers receive NIH grant to develop mRNA vaccines to deter cancer development

Study shows the importance of preserving microglia and Sirt1 functional efficiency for longevity

What is the duration of persistent symptoms after SARS-CoV-2 infection, and what factors are associated with their resolution?

Is placental antibody transfer after COVID-19 vaccination different from that after SARS-CoV-2 infection in pregnant individuals?

‘Impending intergenerational crisis’: Americans with disabilities lack long-term care plans

Delay in consciousness in severe cases of COVID-19 may be caused by neural hibernation

Mosaic nanoparticles displaying spike protein trimers from different coronaviruses elicits cross-reactive protection

A knowledgebase of currently known categorized COVID-19 severity variants

Study evaluates transcutaneous vagus nerve stimulation as treatment for long COVID-chronic fatigue

People of all age groups are at risk of post-COVID-19 syndrome, study says

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