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Positive results from Plexxikon's vemurafenib Phase 2 and 3 trial against metastatic melanoma

Plexxikon Inc., a member of the Daiichi Sankyo Group, today announced efficacy and safety data from the BRIM3 trial, a large, randomized, multi-center Phase 3 clinical study of vemurafenib in patients with previously untreated metastatic melanoma with the BRAFV600 mutation.

6 Jun 2011

New approach for treatment of infections of urinary tract

One in three women will be faced at least once in her life with cystitis, for some the start of a constantly recurring infection. Cystitis is caused by Escherichia coli bacteria which fasten on to the wall of the bladder by means of thread-like structures (pili).

4 Jun 2011

Scientists identify chromosomal mutation responsible for excessive hair growth

Researchers in the Keck School of Medicine of the University of Southern California (USC), together with scientists in Beijing, China, have discovered a chromosomal mutation responsible for a very rare condition in which people grow excess hair all over their bodies.

4 Jun 2011

Individuals with hair loss can benefit from Sequencing technique

Hair loss remains an important distressing side effect for certain patients and individuals and although there are certainly more critical health issues there is no doubt that loss of hair is a stressful experience for men and women.

2 Jun 2011

Patients with advanced NSCLC can benefit from less toxic combination of erlotinib, bevacizumab

The standard treatment for patients with advanced non-small cell lung cancer is a combination of two old-fashioned cytotoxic chemotherapy drugs. The combination, however, comes with substantial toxicity.

2 Jun 2011

SMPX gene mutation causes hereditary hearing impairment

Excessive noise is not the only thing that causes damage to hearing. In many cases, genetic factors are responsible for the loss of hearing at a young age. Researchers at the Max Planck Institute for Molecular Genetics in Berlin together with colleagues from Nijmegen have discovered a previously unknown genetic cause of progressive hearing impairment: the disease is caused by mutations of the SMPX gene, which is located on the X chromosome.

1 Jun 2011

Moisturisers, hair dyes cause serious adverse effects

Permanent hair dye gives the most serious adverse effects, yet there are also many reactions to facial and body moisturisers. This comes from the first report from the National Register of Adverse Effects from Cosmetic Products published by the Norwegian Institute of Public Health.

31 May 2011

Ashland agrees to acquire ISP

Ashland Inc. and International Specialty Products Inc. today announced that Ashland has agreed to acquire privately owned ISP, a global specialty chemical manufacturer of innovative functional ingredients and technologies.

31 May 2011

New biomaterial for repairing damaged human tissue doesn't wrinkle up when stretched

A new biomaterial designed for repairing damaged human tissue doesn't wrinkle up when it is stretched. The invention from nanoengineers at the University of California, San Diego marks a significant breakthrough in tissue engineering because it more closely mimics the properties of native human tissue.

27 May 2011

Caffeine reduces muscle activity in Fallopian tubes

Caffeine reduces muscle activity in the Fallopian tubes that carry eggs from a woman's ovaries to her womb. "Our experiments were conducted in mice, but this finding goes a long way towards explaining why drinking caffeinated drinks can reduce a woman's chance of becoming pregnant," says Professor Sean Ward from the University of Nevada School of Medicine, Reno, USA. Ward's study is published today in the British Journal of Pharmacology

24 May 2011

Viewpoints: IPAB debate; Medicare flap continues; WSJ on VT single payer

While I applaud Ryan for getting the conversation started, I cannot support his specific plan — and therefore will vote "no" on his budget. Why can't I go along with the Ryan Medicare plan?

23 May 2011

Stanford University develops stress-shielding device to reduce surgical scarring

Researchers at Stanford University have developed a special wound dressing that they report was able to significantly reduce scar tissue caused by incisions.

23 May 2011

FDA approves Sutent for patients with progressive neuroendocrine cancerous tumors in pancreas

The U.S. Food and Drug Administration today approved Sutent (sunitinib) to treat patients with progressive neuroendocrine cancerous tumors located in the pancreas that cannot be removed by surgery or that have spread to other parts of the body (metastatic).

21 May 2011

UW's ultrathin laser endoscope gives a Google Earth view of the bladder

Bladder cancer is the fourth-most-common cancer in men and one of the most expensive cancers to treat from diagnosis to death. After initial diagnosis and surgery, patients must return to the urologist at least yearly for a costly, time-consuming and uncomfortable bladder scan. Tumors recur in more than half of patients.

17 May 2011

Researchers untangle two distinct ways in which tumor-suppressor protein works

Researchers at the Stanford University School of Medicine have untangled two distinct ways in which a common, naturally occurring "tumor-suppressor" protein works.

13 May 2011

Study provides evidence that adult planarians harbor pluripotent stem cells

A single adult cell from one of the most impressive masters of regeneration in the animal kingdom - the planarian - is all it takes to build a completely functional new worm, researchers have learned. The study provides the first hard evidence that adult planarians harbor pluripotent stem cells - cells capable of producing the diverse range of tissue types necessary to build a complete animal.

13 May 2011

Plexxikon seeks vemurafenib marketing approval from FDA and EMA for melanoma treatment

Plexxikon Inc., a member of the Daiichi Sankyo Group, today announced that applications for market approval for vemurafenib for the treatment of metastatic melanoma have been submitted to the U.S. Food and Drug Administration and the European Medicines Agency.

11 May 2011

Scientists decipher how hair stem cells can communicate with each other

In one of the first studies to look at the population behavior of a large pool of stem cells in thousands of hair follicles - as opposed to the stem cell of a single hair follicle - Keck School of Medicine of USC scientists deciphered how hair stem cells in mice and rabbits can communicate with each other and encourage mutually coordinated regeneration, according to an article published in the April 29 edition of the journal Science.

10 May 2011

Skin cancer prevention tips for anglers

If you love fishing and want to enjoy it well into your senior years then don't mess around with the sun. That's the advice for the 1 million Minnesotans who are expected to hit the water on Saturday for Minnesota's Fishing Opener from a leading Edina plastic and reconstructive surgeon who has treated hundreds of patients over the course of his 15-year career for skin cancer and melanoma.

10 May 2011

CanTeen launches groundbreaking cancer support system

For these young people, a parent’s cancer can cause great disruption to routines and relationships and can contribute to immense feelings of anxiety and isolation. CanTeen offers young people dealing with their parent's cancer a powerful dual support system in the form of an innovative Offspring Support Program (being launched in Melbourne on 11 May and Brisbane on 17 May, with plans to go national) and a practical FREE resource book Now What…? Dealing with your parent’s cancer, which may be the only help they receive during this difficult time.

5 May 2011