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Combination of MEK inhibitors and nilotinib can overcome CML resistance to targeted drug

Cancer Research UK-funded scientists at The Institute of Cancer Research (ICR) have revealed a technique to kill chronic myeloid leukaemia (CML) cells that have stopped responding to a targeted drug, according to research published in Cancer Cell today.

9 Dec 2011

Girls suffer more frequently from chronic pain than boys

Children who suffer from persistent or recurring chronic pain may miss school, withdraw from social activities, and are at risk of developing internalizing symptoms such as anxiety, in response to their pain. In the first comprehensive review of chronic pain in children and adolescents in 20 years, a group of researchers found that more children now are suffering from chronic pain and that girls suffer more frequently from chronic pain than boys.

9 Dec 2011

Scientists uncover three new locations for Crohn's Disease genes

Three new locations for Crohn's Disease genes have been uncovered by scientists at UCL using a novel gene mapping approach.

9 Dec 2011

USPTO issues Diabetes Patent to Omni Bio

Omni Bio Pharmaceutical, Inc. today announced that U.S. Patent No. 8,071,551, entitled "METHODS AND COMPOSITIONS FOR TREATING DIABETES," was issued by the United States Patent and Trademark Office on December 6, 2011. The Diabetes Patent expires in May 2022.

9 Dec 2011

Pharmacyclics, Janssen partner to develop and market PCI-32765 anti-cancer compound

Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson, announced today that it has executed an agreement with Pharmacyclics, Inc. to jointly develop and market the anti-cancer compound, PCI-32765.

9 Dec 2011

FDA approves Boston Scientific's Infinion 16 Lead for chronic pain management

Boston Scientific Corporation announces U.S. Food and Drug Administration (FDA) approval of the Infinion 16 Percutaneous Lead for its Precision Plus Spinal Cord Stimulator (SCS) System, the first rechargeable SCS device for chronic pain management.

9 Dec 2011

FDA advisory panel OKs anemia drug peginesatide

Once approved by the FDA, the once-monthly injection could capture a share of the $3 billion U.S. market for anemia drugs used for kidney dialysis patients, currently dominated by Amgen Inc's blockbuster Epogen. Affymax, which developed the drug with partner Takeda Pharmaceutical Co Ltd, is also expected to price its product below Epogen.

8 Dec 2011

Pending budget cuts could jeopardize health, safety of state's most vulnerable seniors

California's low-income seniors with disabilities are struggling to remain in their homes as public funding for long-term care services shrinks and may be slashed even further, according to a new study by the UCLA Center for Health Policy Research conducted with support from The SCAN Foundation.

8 Dec 2011

Recommendations to address challenges associated with chronic inflammatory diseases

A dramatic increase in the incidence of chronic inflammatory diseases such as asthma, allergy, and irritable bowel syndrome, has led to concern about how modern lifestyles may trigger physiological defense mechanisms.

8 Dec 2011

First study to identify molecular mechanism that links inflammation to cancer epigenetics

Johns Hopkins Kimmel Cancer Center scientists report that sharp rises in levels of reactive oxygen molecules, and the inflammation that results, trigger biochemical changes that silence genes in a pattern often seen in cancer cells. The researchers confirmed this gene-silencing effect in mice that develop inflammation-induced colon cancer.

8 Dec 2011

Ecstasy drug associated with chronic changes in human brain

Recreational use of Ecstasy - the illegal "rave" drug that produces feelings of euphoria and emotional warmth - is associated with chronic changes in the human brain, Vanderbilt University investigators have discovered.

8 Dec 2011

Simple mindful eating, stress-reduction techniques help prevent weight gain in obese women

Many dread gaining weight during the holiday season, but there may be hope for those who find that stress causes them to reach for yet another helping of holiday goodies. In a study by UCSF researchers published online in the Journal of Obesity, mastering simple mindful eating and stress-reduction techniques helped prevent weight gain even without dieting.

8 Dec 2011

Microsoft, GE Healthcare plans to create joint venture

General Electric Company, through its healthcare IT business, and Microsoft Corp. today announced plans to create a joint venture aimed at helping healthcare organizations and professionals use real-time, system-wide intelligence to improve healthcare quality and the patient experience.

8 Dec 2011

Arsenic in rice worrisome

Studies have shown that rice takes up more arsenic from soil than other crops. Now a new study shows that higher arsenic levels are ingested by women who eat as little as half a cup of cooked rice in a day. Currently, there are no limits on the amount of allowable arsenic in rice in the United States. But the Environmental Protection Agency has set arsenic limits in water of 10 parts per billion.

7 Dec 2011

FDA approves changes to REMS for Nplate and Promacta

The approval of changes to the Risk Evaluation and Mitigation Strategies (REMS) for both Nplate (romiplostim) and Promacta (eltrombopag) was announced by the U.S. Food and Drug Administration.

7 Dec 2011

Racial differences in inflammation might explain survival paradox among dialysis patients

In the general population, African Americans die at earlier ages than whites, but among patients on dialysis, African Americans live longer than whites. A new study helps explain this paradox and could help prolong the lives of all patients on dialysis.

7 Dec 2011

Headache affects one of every two HIV/AIDS patients

A University of Mississippi study of headaches among HIV patients is being hailed as a critical step to improving treatment and reducing unnecessary medical costs among sufferers.

7 Dec 2011

New research on bed bug's ability to withstand genetic bottleneck of inbreeding

New research on the bed bug's ability to withstand the genetic bottleneck of inbreeding, announced today at the American Society of Tropical Medicine and Hygiene (ASTMH) annual meeting, provides new clues to explain the rapidly growing problem of bed bugs across the United States and globally.

7 Dec 2011

Study: Number of young people choosing nursing jumps

An increasing number of young men and women are opting for nursing as a career, says a study released Monday by the RAND Corporation. The study may serve to allay fears about a nursing shortage as the health care law is implemented and millions of people without insurance sign up for medical plans. It predicts that if the growth continues, there will be enough nurses to meet national health care needs by 2030.

7 Dec 2011

Combination of cannabinoids and opiates could help reduce chronic pain

A UCSF study suggests patients with chronic pain may experience greater relief if their doctors add cannabinoids - the main ingredient in cannabis or medical marijuana - to an opiates-only treatment. The findings, from a small-scale study, also suggest that a combined therapy could result in reduced opiate dosages.

7 Dec 2011